Abstract：
:Prostate cancer is a health problem in many Countries worldwide. Understanding the essential function of androgens in the prostate physiology led to the development of hormonal blockade as a therapeutic option in advanced disease, with limited response with time and development of resistance. In this stage, where castration resistant prostate cancer (CRPC) is defined, it is associated with poor prognosis because survival varies between 18 and 24 months. Even with castration levels, tumors are dependent on the functional androgen receptor (AR). In this paper, we analyze pretreatment clinical parameters such as prognostic or progression-predictive biomarkers, castration resistance mechanisms, the development of new technologies for the use of the so called liquid biopsies from biological ayufluids and the identification of circulating tumor cells as CRPC response and progression biomarkers. Currently ongoing clinical trials are partially oriented to the search of new prognostic and predictive biomarkers, that will enable to open up precision medicine and so to improve oncological patient's quality of life with it.
journal_name
Arch Esp Uroljournal_title
Archivos espanoles de urologiaauthors
Pascual Piédrola JI,Hevia Suárez M,Ancizu Markert FJ,García Cortés A,Doménech López P,Chiva San Román S,Velis Campillo JM,Díez-Caballero Alonso F,Robles García JE,Rosell Costa D,Villacampa Aubá F,de Fata Chillón FR,Miñana López Bsubject
Has Abstractpub_date
2018-09-01 00:00:00pages
704-710issue
8eissn
0004-0614issn
1576-8260journal_volume
71pub_type
杂志文章,评审abstract：OBJECTIVES:Megacalycosis or Puigvert's disease is a clinical entity characterized by dilatation of all renal calyces without dilatation of the renal pelvis or ureter in the absence of any obstructive factor. To date, its pathogenesis remains unclear. The rarity of this disease and the importance of making a correct dif...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：1995-04-01 00:00:00
abstract：OBJECTIVE:To describe a case treated with a new technique in our therapeutic algorithm for non-neurogenic vesicourethral dysfunction. METHODS/RESULTS:A 47-year-old female underwent retropubic urethropexy for stress urinary incontinence. She remained incontinent due to detrusor instability to a degree that was socially...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1998-04-01 00:00:00
abstract：OBJECTIVES:We report the case of a patient who had underwent surgery for a clear cell renal carcinoma 2 years before presenting with metastasic extension to bladder on follow-up. METHODS:Radiological finding of a bladder mass during follow-up after nephrectomy. RESULTS:TURBT was carried out with the pathologic report...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2004-12-01 00:00:00
abstract：OBJECTIVE:We report the case of a 33 year old female presenting with an upper pole renal mass suggestive of renal cell carcinoma which in the pathological specimen resulted to be a retained surgical gauze. METHODS/RESULTS:The case of a female patient with history of previous nephrolithotomy 5 years before who presente...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2002-10-01 00:00:00
abstract：OBJECTIVES:This analyzes the usefulness of transvaginal endosonography before and after surgery in patients with stress urinary incontinence. METHODS:We evaluated the bladder contour in 50 patients by transvaginal endosonography and the distance from the bladder neck to the pubis was measured with and without stress. ...
journal_title：Archivos espanoles de urologia
pub_type： 临床试验,杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：UNLABELLED:We report the case of a 65-year-old man who presented with a right testicular mass and synchronous involvement of skin and Waldeyer's ring. These facts led us to the working diagnosis of malignant primary testicular lymphoma. MATERIAL/RESULTS:We present the case with comments and make a bibliographic review...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2009-07-01 00:00:00
abstract：OBJECTIVES:To analyze the evolution of prostate cancer (PCa) in our community health area over the last years, in terms of incidence, clinical-epidemiological characteristics, and cancer-specific mortality. METHODS:Retrospective analysis of the medical records of patients with PCa in our hospital over the 1991-2003 pe...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2004-10-01 00:00:00
abstract：:Since the introduction of extracorporeal shock wave lithotripsy and the various modalities of endoscopic surgery, the number of open procedures for the treatment of urolithiasis has decreased dramatically. The use of these techniques in the management of easier cases leaves no doubt, but there is still some controvers...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2011-04-01 00:00:00
abstract：OBJECTIVE:Cystic tumors of the adrenal gland are uncommon, but are being increasingly more frequently diagnosed during routine radiological evaluation as "incidentalomas". We discuss the differential diagnosis, therapeutic approach and the existing controversies concerning the management of this tumor type. METHODS:Tw...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
abstract：OBJECTIVES:To evaluate the results of this surgical treatment of hydrocele over the first four years of integration of the Urology Department in the Major Ambulatory Surgery Unit in our Hospital. METHODS:From January 2000 to July 2004 we have performed 167 hydrocelectomies as ambulatory surgery in 152 patients (15 cas...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：10.4321/s0004-06142005000500003
更新日期：2005-06-01 00:00:00
abstract：:We present our experience in 61 patients with partial or complete staghorn stone who underwent combined treatment with PCN and ESWL. We excluded the cases with an additional factor complicating staghorn stone, such as horseshoe kidney, severe ectopic, mal-rotated or high, with pyeloureteral junction stricture, etc. Th...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1993-10-01 00:00:00
abstract：OBJECTIVES:To report one case of pseudotumoral lesion of the iliac ureter with obstructive uropathy leading to loss of function of the renal unit. METHODS:66-year-old male being studied for BPH who presents with a self-limited monosymptomatic hematuria. RESULTS:Renal ultrasound detected grade II pyelocaliectasis of t...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：10.4321/s0004-06142005000400011
更新日期：2005-05-01 00:00:00
abstract：OBJECTIVES:To describe a roadmap of the most representative milestones and considerations in the validation of surgical simulators, especially those of laparoscopic surgery. And additionally, help determine when in this process a simulator can be considered as validated. METHODS:A non-systematic review was carried out...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2019-11-01 00:00:00
abstract：OBJECTIVES:To report the principles of penile resculpturing of different deformities caused by M. Peyronie: restoration of penile length, girth and shape with or without penile prosthesis implantation. METHODS:In the period between February 2007 and March 2009, we performed grafting surgery for M. Peyronie in 98 patie...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2010-11-01 00:00:00
abstract：:Penile urethra stenoses generally appear as a sequel after acute (sexually transmitted diseases) or chronic urethritis processes, associated with diseases such as lichen sclerosus or as a consequence of traumatism, iatrogeny and forced distention of the urethral lumen. One third of these lesions may be congenital and ...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVE:To describe the clinical and histopathological manifestations of a case of pseudoepitheliomatous, keratotic and micaceous balanitis and review the literature on this rare condition. METHODS:A case of pseudoepitheliomatous, keratotic and micaceous balanitis in a 63-year-old man is presented. The lesion appear...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
abstract：OBJECTIVE:The results of in situ dissolution of a cystine calculus is described. This approach was attempted in a female patient for whom surgery was not considered to be the best therapeutic option. METHODS:An obstructive cystine calculus was treated by in situ litholysis using N-acetylcysteine applied locally via tw...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：1995-11-01 00:00:00
abstract：OBJECTIVE:To discuss briefly the new therapeutic strategies for poor-prognosis testicular germ cell cancer. METHODS:The use of new drugs in first line chemotherapy, intensive alternating and sequential chemotherapy and high dose chemotherapy with autologous bone marrow or stem cell transplantation are briefly discusse...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2000-07-01 00:00:00
abstract：:The present article studied the biological behaviour of T4a versus T4b tumors. Of 29 patients with T4a tumors, 24 were treated by radical cystectomy and 5 were treated by diversion alone on detecting pathologic gross adenopathies at laparotomy. Of these 10/28 (35.7%) are alive and tumor-free. Of 11 patients with T4b t...
journal_title：Archivos espanoles de urologia
pub_type： 临床试验,杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：OBJECTIVE:Involvement of extralymphatic tissue in chronic lymphocytic leukemia (CLL) is uncommon and that of the epididymis and spermatic cord is rare. This paper describes an unusual case with metastasis to both epididymis and the spermatic cord as the first sign of reactivation of CLL. METHODS/RESULTS:A patient with...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1997-03-01 00:00:00
abstract：:Penile cancer is a radiocurable disease. The different types of radiotherapy (RT)-brachytherapy, plesiotherapy, external beam radiation therapy-have proven valid in the treatment of the primary tumor allowing preservation of the penis and sexual function. RT is even an option in candidates for surgery who reject surge...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2011-05-01 00:00:00
abstract：:From a series of 5000 cases that had undergone extracorporeal shock wave lithotripsy at the Hospital Clinico Quirúrgico "Hermanos Ameijeiras" from March, 1986 to April, 1988, 220 cases that required percutaneous nephrostomy due to obstructive hydronephrosis from stone fragments were studied. We analyzed the clinical, ...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1993-07-01 00:00:00
abstract：OBJECTIVES:The aim of this review is to evaluate the place of transurethral resection of the prostate (TURP) in patients with elevated and/or rising prostate specific antigen (PSA). The role of TURP in these patients is assessed in symptomatic as well as in asymptomatic patients. METHODS:Current literature (1987-2009)...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2010-07-01 00:00:00
abstract：:We report 14 cases of primary retroperitoneal tumor and one retroperitoneal papillary cystoadenoma in a patient who had undergone hysterectomy and bilateral adnexectomy for uterine myomatosis 15 years before the onset of the clinical features that led to the diagnosis of retroperitoneal tumor. For this reason, we beli...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：1991-10-01 00:00:00
abstract：OBJECTIVE:We describe the case of a young male presenting with non-specific abdominal symptoms on follow-up after radical nephrectomy for renal carcinoma leading to the finding of local recurrence and peritoneal metastases. A second exploratory laparotomy was carried out for tumor reduction, but it was followed by fast...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：10.4321/s0004-06142006000900015
更新日期：2006-11-01 00:00:00
abstract：OBJECTIVE:To report a case of laparoscopic radical cystectomy and pelvic lymphadenectomy with vaginal extraction of the surgical specimen in an elderly patient with muscle invasive bladder tumor. METHOD:A 78 year old patient with history of hematuria was diagnosed of muscle invasive bladder cancer. Laparoscopic radica...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：10.4321/s0004-06142009000400007
更新日期：2009-05-01 00:00:00
abstract：OBJECTIVE:To analyze the prevalence of neoplasms in renal transplant patients and the relative risk for each tumor type according to the immunosuppression regimen. METHODS:609 renal transplants were reviewed. The risk index was determined by the ratio of the cases observed and predicted. RESULTS:Tumor prevalence was ...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1997-04-01 00:00:00
abstract：OBJECTIVE:To define, based on PSA value, Gleason score (GS), clinical stage and age, those patients diagnosed with asymptomatic prostate cancer whose cases warrant further study of bone metastasis (BMet). METHODS:From January 2006 to May 2010, we evaluated 263 patients diagnosed with prostate cancer who were chosen fo...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2015-03-01 00:00:00
abstract：OBJECTIVE:To describe an additional case of incomplete sagittal septum of the bladder. METHODS:A case of incomplete sagittal septum of the bladder in a young, asymptomatic patient with paralysis of both lower limbs is presented and literature is briefly reviewed. RESULTS:The diagnosis was made by intravenous urograph...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2000-09-01 00:00:00
abstract：OBJECTIVE:We report three cases of pelvic lipomatosis, and from them we discuss its diagnostic and therapeutic considerations. METHODS/RESULTS:Three patients, 71, 65 and 61 years old respectively, presented with irritative lower urinary tract symptoms. Intravenous pyelogram (IVP) and CT scan were performed as diagnost...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2002-10-01 00:00:00
