Abstract:
OBJECTIVE:To discuss briefly the new therapeutic strategies for poor-prognosis testicular germ cell cancer. METHODS:The use of new drugs in first line chemotherapy, intensive alternating and sequential chemotherapy and high dose chemotherapy with autologous bone marrow or stem cell transplantation are briefly discussed. RESULTS/CONCLUSIONS:Despite the current advancements in the treatment of germ cell tumors, approximately 50% of patients with poor-prognosis germ cell tumors according to the IGCCCG classification die from their disease. In order to improve the results in this group of patients, new therapeutic strategies are currently being investigated, such as the introduction of new drugs to the first line chemotherapeutic regimen. However, randomized studies have shown no benefit from the use of ifosfamide. Phase II trials have shown promising results with intensive alternating and sequential chemotherapy, although the only phase III randomized trial that has been conducted comparing BOP-VIP with BEP showed no advantages. Some phase II trials using high-dose chemotherapy with hematopoietic support in first line treatment of poor-prognosis germ cell tumors have shown promising results. Randomized trials are necessary in this group of patients in order to achieve therapeutic advancements.
journal_name
Arch Esp Uroljournal_title
Archivos espanoles de urologiaauthors
Arance A,García del Muro X,Montes A,Germà Lluch JRsubject
Has Abstractpub_date
2000-07-01 00:00:00pages
517-21issue
6eissn
0004-0614issn
1576-8260journal_volume
53pub_type
杂志文章,评审abstract::Instrumental ureterotomy is considered, in this paper, as alternative therapy in ureteral stenoses. There is a description of a special instrument, designed for the treatment of this pathology and there is also a description of the technique to be applied. ...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章
doi:
更新日期:1981-03-01 00:00:00
abstract::We present a case of vesical extrophy complicated by an adenocarcinoma in a 35-year old patient. It is this type of neoformation which most frequently affects the extrophic bladder and which, contrary to what has happened in most of the cases published, quickly presented bone and skin metastases. ...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章
doi:
更新日期:1981-05-01 00:00:00
abstract::Rectal involvement secondary to adenocarcinoma of the prostate is uncommon and carries a poor prognosis. Distinguishing secondary from primary rectal tumors is mandatory, since each condition warrants a completely different treatment. There are at least five forms of clinicopathological involvement, depending on the r...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章
doi:
更新日期:1993-03-01 00:00:00
abstract::We report on a patient with a long history of rheumatoid arthritis who consulted for intense hematuria that was initially ascribed to carcinoma of the bladder. Subsequent patient evaluation, however, disclosed amyloidosis of the urinary bladder. The literature on amyloidosis of the urinary tract is reviewed. A detaile...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
abstract:OBJECTIVE:To report one case of transitional cell carcinoma with areas of small cell carcinoma presenting in its evolution an adrenal metastasis with the neuroendocrine component only. We perform a bibliography review for the cases of small cell carcinoma of the bladder, its epidemiology, prognosis and treatment. METH...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章,评审
doi:10.4321/s0004-06142007000300016
更新日期:2007-04-01 00:00:00
abstract::We present our experience with bladder substitution in radical surgery for bladder cancer. Ileocapsuloplasty was performed in 40 patients. There were 2 postoperative deaths and 11 patients died from tumor recurrence or progression 2 to 10 years later. Two patients had urothelial tumor recurrence in the capsuloplasty. ...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章
doi:
更新日期:1992-11-01 00:00:00
abstract:OBJECTIVE:To report our experience with the management of arterial priapism by embolization. METHODS:Two patients with arterial priapism secondary to perineal trauma are described. Diagnostic evaluation included intracorporal blood gas, echo Doppler and selective pudendal arteriographic assessment. Treatment was by se...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章
doi:
更新日期:1999-04-01 00:00:00
abstract::The authors draw attention to the potential danger of urinary schistosomiasis in Spain, pointing out the nuclei in the country which present snails suitable for being intermediary carriers. They present one case, not autochthonous, observed in León and they point out the possible increase in this parasitosis, due to t...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::We report 16 cases of priapism in 13 of 404 patients who received intracavernous injection of vasoactive drugs to induce erection. In 10 patients the complication presented following injection of papaverine and phentolamine in combination. Despite reducing the dose of both agents, one patient had another episode of pr...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章
doi:
更新日期:1992-10-01 00:00:00
abstract:OBJECTIVES:To analyze the incidence of tumoral satellite nodules in renal carcinoma, study the main features of the primary tumor and establish an approach to determine the risk of multicentricity. METHODS:We analyzed 286 radical nephrectomies due to renal carcinoma. Twenty-nine cases (10.13%) that had intrarenal tumo...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章
doi:
更新日期:1996-07-01 00:00:00
abstract:OBJECTIVES:To describe the technique and preliminary results of the laparoscopic cystectomy as well as to review current indications and limitations of a nouvel surgical approach for a classical operation. METHODS:A careful description of the key points of the technique of laparoscopic cystectomy and creation of an il...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章,评审
doi:
更新日期:2002-07-01 00:00:00
abstract:OBJECTIVES:Giant hydronephrosis, defined as the presence of a liquid volume over 1000 ml within the urinary collector system, is a rare clinical entity, the diagnosis of which is an excellent exercise because it lacks of a defined clinical presentation. METHODS/RESULTS:We report the case of a 66-year-old male under st...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章
doi:10.4321/s0004-06142006000100014
更新日期:2006-01-01 00:00:00
abstract::Four hundred and thirty-eight men with histologically confirmed prostatic adenocarcinoma were diagnosed consecutively and followed up closely for up to ten years. The mean age at presentation was 72.5 years and ranged from 45.3 to 91.0 years. Half of the total presented with symptoms of increasing urinary outflow obst...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章,评审
doi:
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVES:Ureterointestinal stricture represents a serious problem whose management has traditionally been by open surgery. Endourological treatment is an alternative that is generally free from the complications of open surgery, but with a lower success rate. The efficacy of endourological treatment is analyzed in 14...
journal_title:Archivos espanoles de urologia
pub_type: 临床试验,杂志文章,评审
doi:
更新日期:1995-09-01 00:00:00
abstract::We report on a 62-year-old female patient who consulted for G.I. tract disorders and was diagnosed as having renal oncocytoma. The rarity of this disease entity prompted us to report on this case, highlighting the malignant course of this tumor type despite its apparently benign features. ...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章,评审
doi:
更新日期:1989-04-01 00:00:00
abstract::The research of the origin and development of the Medicalhyphen;surgical specialties in our environment has been, to my knowledge, limited. The aim of this work is to review it in reference to Urology, one of the first specialties developed in Mallorca during the second half of the XIX Century and the beginning of the...
journal_title:Archivos espanoles de urologia
pub_type: 历史文章,杂志文章
doi:
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:Report of one case of desmoid tumor in a patient who had been treated of a testicular seminoma 26 months before, with excision of a retroperitoneal mass and chemotherapy. On followup he presented with a mesenteric abdominal mass which was clinically labeleled as a recurrence of the seminoma. RESULTS:Histolog...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章
doi:10.4321/s0004-06142007000600017
更新日期:2007-07-01 00:00:00
abstract:OBJECTIVES:To assess the feasibility and a validity of the Spanish version of the FACT-P and its relation to urinary symptoms. METHODS:The Spanish version of the FACT-P was self-administered to 60 Prostate Cancer patients (pts) waiting to undergo radical treatment and 20 age-matched controls (con) with a negative biop...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章
doi:
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVE:To compare c-kit-positive interstitial Cajal-like cells (ICC) and Caveolin-1 protein levels as a pacemaker and signaling molecules, on ureteropelvic junction (UPJ) specimens, between two groups of pediatric patients with and without ureteropelvic junction obstruction (UPJO). METHODS:We evaluated the UPJ spec...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章
doi:
更新日期:2019-09-01 00:00:00
abstract::We describe the unusual case of a young male who presented lower urinary tract obstruction secondary to a bladder-prostate embryonal rhabdomyosarcoma. Initially he was treated with multiagent chemotherapy and radiotherapy in an attempt to preserve bladder function, but eventually radical cystoprostatectomy was warrant...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章
doi:
更新日期:1994-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of the Anderson-Hynes pyeloplasty in 47 patients with pelviureteric junction syndrome and to compare our results with the reported results for open surgery and other techniques. METHODS:The records of 47 patients (21 males, 26 females) with pelviureteric junction syndrome treated at ...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章
doi:
更新日期:1999-06-01 00:00:00
abstract::This study was conducted to assess the clinical reliability of the prostatic Urolume Wallstent for symptomatic BPH patients. One hundred patients were treated under intravenous sedation or local anesthesia. Pre- and postoperative patient evaluation included scoring of subjective symptoms, physical examination, laborat...
journal_title:Archivos espanoles de urologia
pub_type: 临床试验,杂志文章
doi:
更新日期:1994-11-01 00:00:00
abstract::Vesicoureteral reflux remains one of the most controversial subjects in paediatric urology. The flooding of publications on reflux makes the understanding of this anomaly and its treatments quite opaque. Evidence Based Medicine might be a helpful tool to clarify the various approaches of reflux reflected in 6.715 publ...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章,评审
doi:10.4321/s0004-06142008000200008
更新日期:2008-03-01 00:00:00
abstract::Three-dimensional, high-definition images, small instruments with endowrist technology, ergonomic position and the easiness to teach, are possibly the main reasons why robotic surgery will continue to gain ground to others forms of surgery. The current applications of robotics in functional urology are: the correction...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章
doi:
更新日期:2019-04-01 00:00:00
abstract::We present 7 cases of ureterocele with secondary lithiasis, which constitute 15% of all our cases of ureterocele. From the clinical point of view, the symptoms are not different from those of these two separate pathologies. Nephroureteral colics associated with a low ureteral syndrome were the most frequent cause of t...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章
doi:
更新日期:1978-03-01 00:00:00
abstract:OBJECTIVE:To report an unusual case of renal tumor and review the literature. METHODS:We present a 20 years old female with a history of acute right pyelonephritis. The ultrasound study revealed a tumor-like image in the lower pole of the right kidney . The CT-scan showed a mixed solid and cystic mass of 7 cm. in the...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章
doi:
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVES:To report our experience in the diagnosis and treatment of the lower urinary tract obstruction after urinary incontinence corrective surgery, analysing the different techniques performed, retropubic or vaginal urethrolysis. METHODS:We report a series of 14 patients with the diagnosis of obstruction after in...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章
doi:
更新日期:2002-11-01 00:00:00
abstract:OBJECTIVES:To report one case of giant inguinal scrotal bladder hernia associated with incipient bilateral obstructive uropathy. METHODS:We report the case of a 54-year-old male patient presenting with two-time interrupted voiding, with the need of scrotal compression to complete voiding. Physical examination showed a...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章
doi:
更新日期:2005-09-01 00:00:00
abstract::Holmium laser has been established asthe gold-standard for the ureteroscopic management of urinary stone disease. However the role of laser inpercutaneous nephrolithotomy (PCNL) varies, as multiple energy sources and lithotripters are available. Currently, lasers are becoming more relevant with the development of seve...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章,评审
doi:
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVE OF THE REVIEW:Robot assisted Radical prostatectomy (RARP) has generated a new trend in the binomial teaching/learning, grouping these techniques in training modules such as theoretical learning, practice, personalized counseling, and modern tools like simulation and practice in virtual models. This review sum...
journal_title:Archivos espanoles de urologia
pub_type: 杂志文章
doi:
更新日期:2019-04-01 00:00:00