The two β-oxidation sites in pea cotyledons : Carnitine palmitoyltransferase: location and function in pea mitochondria.

Abstract:

:Two sites for β-oxidation of fatty acids in pea (Pisum sativum L.) cotyledons exist. One site is the microbody, the other the mitochondrion. Mitochondrial β-oxidation of fatty acids is carnitine-dependent. The fatty acid permeates the membrane as palmitoylcarnitine which is formed from cytosolic-side palmitoyl-CoA by a carnitine palmitoyltransferase located on the exterior face of the inner mitochondrial membrane as a peripheral protein. A single-gated pore integral membrane translocator is proposed to exchange the palmitoylcarnitine for carnitine or acetylcarnitine across the membrane. An internal (matrix side) carnitine palmitoyltransferase then reforms palmitoyl-CoA which enters β-oxidation and subsequently the tricarboxylic-acid cycle.

journal_name

Planta

journal_title

Planta

authors

Thomas DR,Wood C

doi

10.1007/BF00402972

subject

Has Abstract

pub_date

1986-06-01 00:00:00

pages

261-6

issue

2

eissn

0032-0935

issn

1432-2048

journal_volume

168

pub_type

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