Gastric ulceration as a complication of hepatic artery infusion chemotherapy.

Abstract:

:Based upon the cases reported in this paper and upon a literature review encompassing 1,783 patients having received HAIC, it is our opinion that upper gastrointestinal tract ulceration is a potentially significant complication of hepatic artery infusion chemotherapy. In addition, we believe that the mechanism responsible for HAIC-induced ulceration often involves direct perfusion of the gastric arterial supply with chemotherapeutic agents. The occurrence of ulcerations in patients with surgically placed catheters is disconcerting, and does not allow for any apparent easy method of alleviating HAIC-induced ulceration. Clinicians should be alerted to the possibility of gastric and duodenal ulceration in patients treated with HAIC, and should afford particular attention to gastrointestinal symptoms during hepatic artery infusion chemotherapy.

journal_name

South Med J

journal_title

Southern medical journal

authors

Bible KC,Hatfield AK,Lansford CL,Kammer BA

doi

10.1097/00007611-198606000-00026

subject

Has Abstract

pub_date

1986-06-01 00:00:00

pages

755-7

issue

6

eissn

0038-4348

issn

1541-8243

journal_volume

79

pub_type

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