Abstract:
BACKGROUND:Considering the surgical safety and perioperative complications, simultaneous resection after neoadjuvant therapy is not commonly recommended. METHODS:A total of 253 patients were included in study. Comparison of the short-term outcomes was performed after propensity score adjustment in Group A (n = 96) and Group B (neoadjuvant therapy, n = 96). RESULTS:There was no postoperative mortality. After matching, the differences from surgical confounders were well-balanced. Morbidity (15.6% vs. 15.6%, p = 0.981), and Clavien-Dindo grade of complications (p = 0.710) were similar. No difference was found when the complications were divided according to the origin (general, colorectal and hepatic). Length of the hospital stays also did not differ between the groups (p = 0.482). More importantly, there was no increase in the number of patients with delayed adjuvant treatment after surgery in Group B. CONCLUSIONS:Neoadjuvant treatment did not increase morbidity, length of hospital stays and influence adjuvant treatment after simultaneous resection.
journal_name
Am J Surgjournal_title
American journal of surgeryauthors
Wu Y,Liu F,Song W,Liang F,Wang L,Xu Ydoi
10.1016/j.amjsurg.2018.09.019subject
Has Abstractpub_date
2019-11-01 00:00:00pages
894-898issue
5eissn
0002-9610issn
1879-1883pii
S0002-9610(18)30766-9journal_volume
218pub_type
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journal_title:American journal of surgery
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