A prognostic nomogram to predict overall survival in women with recurrent ovarian cancer treated with bevacizumab and chemotherapy.

abstract：OBJECTIVE:Neuropilin-1 (NRP-1) is a receptor for both semaphorin and vascular endothelial growth factor and is up-regulated in a variety of human cancers. While there are some reports of NRP-1 expression in ovarian neoplasm, those results differ in pattern of its expression and its role in ovarian cancer is still uncle...

journal_title：Gynecologic oncology

authors： Baba T,Kariya M,Higuchi T,Mandai M,Matsumura N,Kondoh E,Miyanishi M,Fukuhara K,Takakura K,Fujii S

更新日期：2007-06-01 00:00:00

abstract：INTRODUCTION:Extrarenal Wilms' tumors are rare, with only 55 well-documented cases in the literature and only 4 confined to the uterus. A fifth case along with review of the current literature is presented. CASE:A 13-year-old girl presented with a 2-month history of irregular vaginal spotting. A 6.5 x 4.5 x 2.5-cm pol...

journal_title：Gynecologic oncology

authors： Babin EA,Davis JR,Hatch KD,Hallum AV 3rd

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:Although the relationship between human papilloma virus (HPV) and cervical cancer is well established, the prognostic value of HPV status has not been determined, largely because previous studies have yielded conflicting results. This study aimed to investigate the prognostic value of pre-treatment HPV DNA fo...

journal_title：Gynecologic oncology

authors： Chong GO,Lee YH,Han HS,Lee HJ,Park JY,Hong DG,Lee YS,Cho YL

更新日期：2018-01-01 00:00:00

abstract：:The clinical pharmacology of cisplatin was determined in six patients with malignant ascites secondary to ovarian cancer, and in one patient with peritoneal mesothelioma, following intraperitoneal administration of cisplatin (25-60 mg/m2). The drug was administered in 1 liter of normal saline as a 15- to 30-min infusi...

journal_title：Gynecologic oncology

authors： Lopez JA,Krikorian JG,Reich SD,Smyth RD,Lee FH,Issell BF

更新日期：1985-01-01 00:00:00

abstract：:MicroRNA molecules are small, single-stranded RNA molecules that function to regulate networks of genes. They play important roles in normal female reproductive tract biology, as well as in the pathogenesis and progression of epithelial ovarian cancer. DROSHA, DICER, and Argonaute proteins are components of the microR...

journal_title：Gynecologic oncology

authors： Wang X,Ivan M,Hawkins SM

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:Advanced ovarian cancer (OC) commonly spreads to cardiophrenic lymph nodes (CPLNs), and is often visible on preoperative imaging. We investigated the prognostic significance of abnormal CPLNs in OC detected by preoperative CT scans using three different definitions. METHODS:Patients undergoing primary debulk...

journal_title：Gynecologic oncology

authors： Mert I,Kumar A,Sheedy SP,Weaver AL,McGree ME,Kim B,Cliby WA

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:Efflux transporters of the ATP-binding cassette (ABC) family are major determinants of chemoresistance in tumor cells. This study examined associations between functional variants in ABCB1, ABCC2 and ABCG2 genes and clinical outcomes in patients with epithelial ovarian/primary peritoneal cancer (EOC/PPC) follow...

journal_title：Gynecologic oncology

authors： Tian C,Ambrosone CB,Darcy KM,Krivak TC,Armstrong DK,Bookman MA,Davis W,Zhao H,Moysich K,Gallion H,DeLoia JA

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:Hydroxysteroid-dehydrogenase-17b (HSD17b) genes control the last step in estrogen biosynthesis. The isoenzymes HSD17b2 and HSD17b4 in the uterus preferentially catalyze the conversion of estradiol, the most potent and active form of estrogen, to estrone, the inactive form of estrogen. Endometrial adenocarcino...

journal_title：Gynecologic oncology

authors： Karageorgi S,McGrath M,Lee IM,Buring J,Kraft P,De Vivo I

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:This study's objective was to quantify the impact (utility) of common complications of early cervical cancer treatment on quality of life (QOL). Utilities assigned by survivors were compared to those assigned by providers. METHODS:30 survivors of early cervical cancer identified from our Tumor Registry and 1...

journal_title：Gynecologic oncology

authors： Einstein MH,Rash JK,Chappell RJ,Swietlik JM,Hollenberg JP,Connor JP

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVES:The effect on progesterone and estrogen receptor expression in glands and stroma after two different treatment regimens of endometrial hyperplasia was determined. METHODS:Pre- and post-treatment paraffin-embedded endometrial hyperplasia specimens from women treated with levonorgestrel (LNG) intrauterine dev...

journal_title：Gynecologic oncology

authors： Vereide AB,Kaino T,Sager G,Arnes M,Ørbo A

更新日期：2006-05-01 00:00:00

abstract：:Aggressive tumor reduction surgery has been widely used in patients with advanced stage epithelial ovarian carcinoma before initiation of cytotoxic chemotherapy. No randomized controlled trial has been carried out to confirm the benefits of such procedures. To examine the role of cytoreductive surgery in the managemen...

journal_title：Gynecologic oncology

authors： Le T,Krepart GV,Lotocki RJ,Heywood MS

更新日期：1997-11-01 00:00:00

abstract：:Symptomatic uterine lymphangioleiomyomatosis (LAM) simulating high-stage uterine sarcoma in a patient with tuberous sclerosis complex is reported. A 49-year-old female presented with abdominal pain and anemia. Preoperative workup revealed a uterine mass and a large amount of peritoneal free fluid and possible metastat...

journal_title：Gynecologic oncology

authors： Longacre TA,Hendrickson MR,Kapp DS,Teng NN

更新日期：1996-12-01 00:00:00

abstract：:Ninety-two patients with early invasive carcinoma of the cervix (5 mm or less) treated between July 1977 and June 1990 are reviewed. Eighty patients had squamous cell carcinomas and 12 had adenocarcinomas. The diagnosis was established by conization in 77 of 92 (83.6%) patients. Thirty-six patients (39%) had a depth o...

journal_title：Gynecologic oncology

authors： Jones WB,Mercer GO,Lewis JL Jr,Rubin SC,Hoskins WJ

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVE:Despite the fact that endometrial cancer commonly occurs in elderly women, little is known about the outcome of the oldest old, those > 80 years of age. We examined the patterns of care and outcome of the oldest old women with endometrial cancer. METHODS:An analysis of women > 65 years of age with endometrio...

journal_title：Gynecologic oncology

authors： Wright JD,Lewin SN,Barrena Medel NI,Sun X,Burke WM,Deutsch I,Herzog TJ

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:Our goal was to pragmatically describe patient reported outcomes (PROs) in a typical clinic population of vulvar cancer patients, as prior studies of vulvar cancer PROs have examined clinical trial participants. METHODS:A prospective PRO program was implemented in the Gynecologic Oncology clinic of a tertiar...

journal_title：Gynecologic oncology

authors： Alimena S,Sullivan MW,Philp L,Dorney K,Hubbell H,Del Carmen MG,Goodman A,Bregar A,Growdon WB,Eisenhauer EL,Sisodia RC

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:The prognosis of cancer patients with distant metastases is extremely poor. CASE:A 51-year-old Japanese woman with Stage IIIc serous cystoadenocarcinoma of the ovary achieved complete remission. At 30 and 39 months after the initiation of therapy, solitary brain and then spleen metastases without intraperit...

journal_title：Gynecologic oncology

authors： Mikami M,Suzuki A,Takehara K,Komiyama S,Ishikawa M,Hirose T

更新日期：2003-08-01 00:00:00

abstract：:The causes of death in long-term survivors after resection of cervical cancer were investigated in a follow-up study of 375 women, focusing especially on the postoperative development of second primary cancers. The 5- and 10-year overall survival rates were 75.0 and 66.0%, respectively, in cases that showed frank inva...

journal_title：Gynecologic oncology

authors： Tominaga K,Koyama Y,Sasagawa M,Obata N,Kamata H,Yamaguchi E,Nagai M

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVE:To compare the short-term surgical outcome of patients undergoing robotic radical hysterectomy (RRH) versus open radical hysterectomy (ORH) for the treatment of early stage cervical cancer. METHODS:IRB approval was obtained for a retrospective chart review of all radical hysterectomies (RHs) for Stage I and ...

journal_title：Gynecologic oncology

authors： Ko EM,Muto MG,Berkowitz RS,Feltmate CM

更新日期：2008-12-01 00:00:00

abstract：:This report presents 13 patients with epithelial ovarian neoplasms of low malignant potential. Ten patients had serous tumors, 1 had a mucinous tumor, and 2 had endometrioid tumors. Two had Stage I disease, 4 had Stage II disease, and 7 had Stage III disease. All were treated with melphalan. Second-look laparotomy was...

journal_title：Gynecologic oncology

authors： O'Quinn AG,Hannigan EV

更新日期：1985-06-01 00:00:00

abstract：OBJECTIVE:Microsatellite instability (MSI) is a frequent genetic event in the D-loop region (which controls mitochondrial DNA (mtDNA) replication) of mitochondrial genome of endometrial cancer. We therefore investigated the relationship between mtMSI and mtDNA content in endometrial cancer. METHODS:Tumor tissues from ...

journal_title：Gynecologic oncology

authors： Wang Y,Liu VW,Xue WC,Tsang PC,Cheung AN,Ngan HY

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:The goal of this work was to determine the cellular content of inhibin and p53 in granulosa cell tumors (GCTs). METHODS:Clinical records of 47 patients (mean age, 54 years; range, 20-85 years) presenting with GCT surgically managed at our institution were abstracted. International Federation of Gynecology st...

journal_title：Gynecologic oncology

authors： Gebhart JB,Roche PC,Keeney GL,Lesnick TG,Podratz KC

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVE:Perform a systematic review to determine the test performance of HPV mRNA testing compared to DNA testing using CIN2+ as the target condition. METHODS:We searched bibliographic databases (MEDLINE, EMBASE and Cochrane Library) from January 1996 through August 2010 using a predefined search strategy. The refer...

journal_title：Gynecologic oncology

authors： Burger EA,Kornør H,Klemp M,Lauvrak V,Kristiansen IS

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to detect beta-subunit human chorionic gonadotropin (beta(h)CG) mRNA in the peripheral blood samples of patients with nonmetastatic gestational trophoblastic disease (GTD) undergoing hysterectomy. METHODS:Heparinized peripheral blood samples were obtained from four patients with non...

journal_title：Gynecologic oncology

authors： Suzuka K,Matsui H,Iitsuka Y,Sekiya S

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:To compare the incidence of postoperative complications and opioid pain medication usage in gynecologic oncology patients who did and did not receive an epidural prior to undergoing exploratory laparotomy. METHODS:Retrospective cohort study of all patients undergoing exploratory laparotomy with the gynecolog...

journal_title：Gynecologic oncology

authors： Huepenbecker SP,Cusworth SE,Kuroki LM,Lu P,Samen CDK,Woolfolk C,Deterding R,Wan L,Helsten DL,Bottros M,Mutch DG,Powell MA,Massad LS,Thaker PH

更新日期：2019-05-01 00:00:00

abstract：:In a study of 73 patients, diagnosed with recurrent squamous cell carcinoma of the vulva between 1975 and 1990, the effect of clinical variables on the outcome was evaluated. The overall 5-year survival rate was 35.2%. Of the 73 patients, 33 (45.2%) originally had Stage I or II disease and 40 (54.8%) Stage III or IVA;...

journal_title：Gynecologic oncology

authors： Piura B,Masotina A,Murdoch J,Lopes A,Morgan P,Monaghan J

更新日期：1993-02-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to evaluate the effect of number of chemotherapy cycles and other clinical and pathologic factors on progression-free (PFS) and overall survival (OS) in patients with newly diagnosed cervical cancer. METHODS:We identified 118 patients with locally advanced cervical cancer (stages I...

journal_title：Gynecologic oncology

authors： Nugent EK,Case AS,Hoff JT,Zighelboim I,DeWitt LL,Trinkhaus K,Mutch DG,Thaker PH,Massad LS,Rader JS

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:Data has suggested obesity as an independent prognostic factor for lower survival in patients with epithelial ovarian cancer (EOC). We sought to determine if obesity portends a disadvantage to surgical outcomes at the time of initial surgery affecting survival. METHODS:A retrospective chart review of patient...

journal_title：Gynecologic oncology

authors： Matthews KS,Straughn JM Jr,Kemper MK,Hoskins KE,Wang W,Rocconi RP

更新日期：2009-02-01 00:00:00

abstract：:An improved assay for the measurement of human ovarian tumor antigen NB/70K (triton NB/70K assay) has been developed. This assay makes the accurate and reproducible estimation of serum NB/70K possible. Freezing and thawing of serum up to three times or refrigeration of diluted serum up to 7 days does not significantly...

journal_title：Gynecologic oncology

authors： Knauf S,Taillon-Miller P

更新日期：1984-09-01 00:00:00

abstract：OBJECTIVE:Recurrent and advanced cervical cancers are associated with high mortality and a lack of effective treatment options, especially for women who are poor candidates for surgery or radiation therapy. The broad clinical effectiveness and low toxicity of gemcitabine in other human malignancies suggest that it migh...

journal_title：Gynecologic oncology

authors： Mutch DG,Bloss JD

更新日期：2003-08-01 00:00:00

abstract：:Between 1978 and 1983, one hundred and forty-six patients with CIN I-III were treated with the carbon dioxide laser and 129 have been followed for 6 to 58 months. The remission rate was 92.2% after one treatment and 98.4% after two treatments. All persistent lesions were detected within 8 weeks after treatment. After ...

journal_title：Gynecologic oncology

authors： Tsukamoto N

更新日期：1985-07-01 00:00:00