Abstract:
OBJECTIVE:Cognitive reserve (CR) refers to the brain's capacity to cope with pathology in order to minimize the symptoms. CR is associated with different outcomes in severe mental illness. This study aimed to analyze the impact of CR according to the diagnosis of first-episode affective or non-affective psychosis (FEP). METHOD:A total of 247 FEP patients (211 non-affective and 36 affective) and 205 healthy controls were enrolled. To assess CR, common proxies have been integrated (premorbid IQ; education-occupation; leisure activities). The groups were divided into high and low CR. RESULTS:In non-affective patients, those with high CR were older, had higher socioeconomic status (SES), shorter duration of untreated psychosis, and a later age of onset. They also showed greater performance in most cognitive domains. In affective patients, those with a greater CR showed a higher SES, better functioning, and greater verbal memory performance. CONCLUSION:CR plays a differential role in the outcome of psychoses according to the diagnosis. Specifically, in order to address the needs of non-affective patients with low CR, cognitive rehabilitation treatments will need to be 'enriched' by adding pro-cognitive pharmacological agents or using more sophisticated approaches. However, a functional remediation therapy may be of choice for those with an affective psychosis and low CR.
journal_name
Acta Psychiatr Scandjournal_title
Acta psychiatrica Scandinavicaauthors
Amoretti S,Cabrera B,Torrent C,Mezquida G,Lobo A,González-Pinto A,Parellada M,Corripio I,Vieta E,de la Serna E,Butjosa A,Contreras F,Sarró S,Penadés R,Sánchez-Torres AM,Cuesta M,Bernardo M,PEPsGroup.doi
10.1111/acps.12949subject
Has Abstractpub_date
2018-11-01 00:00:00pages
441-455issue
5eissn
0001-690Xissn
1600-0447journal_volume
138pub_type
杂志文章,多中心研究abstract:INTRODUCTION:This paper reviews studies on outcomes of involuntary hospital admissions in general adult psychiatry, and predictors of outcomes. METHOD:Studies assessing observer-rated clinical change and self-rated outcomes were identified. Relevant databases were searched and authors were contacted. Studies were clas...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0447.2006.00823.x
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVE:This study assessed the manner in which insight influenced schizophrenic patients' evaluation of their objective life conditions and the concurrent validity between patients' and clinicians' assessments of patients' global quality of life. METHOD:Forty out-patients who fulfilled DSM-III-R criteria for schizo...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1999.tb00994.x
更新日期:1999-06-01 00:00:00
abstract::A study sample of 50 patients suffering from schizophrenia was examined at readmission and thereafter every second week until each patient had been interviewed five times i.e. eight weeks in total. Three types of recovery are identified, one with full and two with partial recovery of delusional beliefs. In patients wi...
journal_title:Acta psychiatrica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1600-0447.1995.tb09609.x
更新日期:1995-12-01 00:00:00
abstract::In this research we investigated the effects of 4 antipsychotic drugs with different anticholinergic components on different memory functions of schizophrenic patients. Drugs were administered in cumulative doses and memory was tested 90 min after each drug was administered. The results show that chlorpromazine and th...
journal_title:Acta psychiatrica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.1111/j.1600-0447.1992.tb01446.x
更新日期:1992-01-01 00:00:00
abstract::419 patients in Sri Lanka, 150 patients in U.K. and 172 patients in Canada who were suffering from "Functional Psychoses" were interviewed using the Present State Examination to elicit Schneider's First Rank Symptoms (FRS). Nationality and ethnicity were found to be significant variables associated with lower prevalen...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1987.tb02921.x
更新日期:1987-11-01 00:00:00
abstract::We investigated the capacity of several thyroid-axis measures to distinguish between depressed and control subjects and determined whether these variables were related to antidepressant treatment response. We studied 105 subjects who fulfilled the DSM-III-R criteria for a current major depressive episode and 41 volunt...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1997.tb09648.x
更新日期:1997-05-01 00:00:00
abstract::Gender discriminating vocabulary tests administered to a consecutive series of 53 male transsexuals show different results. The Slater Selective Vocabulary Test, Cohen's factors and the Terman-Miles Attitude Interest Analysis Test (M-F) show male transsexuals to have a higher degree of feminization than normal control...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1979.tb06949.x
更新日期:1979-01-01 00:00:00
abstract::On admission, IgA, IgG and IgM concentrations were determined in 76 schizophrenics, and the correlations of these concentrations to the variables relating to psychopathology, background and prognosis were investigated in the present study, which is a part of a more extensive unpublished study. On the basis of factoriz...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1977.tb03560.x
更新日期:1977-09-01 00:00:00
abstract::The validity of a questionnaire developed to assess negative attitudes towards drug therapy by relatives of schizophrenic patients is examined. The questionnaire items are tested against the statement: "Patients should not take drugs, they can only be helped by good advice". The prejudice of relatives of schizophrenic...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1985.tb01269.x
更新日期:1985-02-01 00:00:00
abstract::A total of 1070 men and women aged 65 years and over living in the community in Liverpool were interviewed using the Geriatric Mental State. Diagnoses of depression at case and subcase level were made using the GMS-AGECAT package from an initial interview and at follow-up three years later. Data relating to blood pres...
journal_title:Acta psychiatrica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1600-0447.1995.tb09752.x
更新日期:1995-02-01 00:00:00
abstract:OBJECTIVE:To investigate the predictive value of the Strauss and Carpenter Prognostic Scale (SCPS) for transition to a first psychotic episode in subjects clinically at high risk (CHR) of psychosis. METHOD:Two hundred and forty-four CHR subjects participating in the European Prediction of Psychosis Study were assessed...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2012.01899.x
更新日期:2013-01-01 00:00:00
abstract::The clinical effect of cis(Z)-clopenthixol has been compared with that of clopenthixol, which is a mixture of the pharmacologically active cis(Z)-isomer and the inactive trans(E)-isomer. In the 2-month double-blind trial were included 57 psychotic patients, mainly schizophrenics. Ratings evaluating severity of illness...
journal_title:Acta psychiatrica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.1111/j.1600-0447.1978.tb03570.x
更新日期:1978-11-01 00:00:00
abstract:OBJECTIVE:Renewed insight into dose-related effects of sertindole and haloperidol was sought by re-analysing published data for antipsychotic effect, extrapyramidal effect, and patient wellbeing - i.e., the important pharmacopsychometric triangle domains. METHOD:Selected Positive and Negative Syndrome Scale (PANSS) su...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1600-0447.2010.01581.x
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVE:While findings are contradictory, many studies report that long Duration of Untreated Psychosis (DUP) correlates with poorer outcome in first episode psychosis. In an outcome study of first-episode psychosis, we compared the patients who refused to participate in a follow-along with those who consented to est...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2004.00381.x
更新日期:2004-10-01 00:00:00
abstract:OBJECTIVE:Chronically mentally ill patients in community mental health care report a better quality of life (QOL) than those in long-term hospital care, which suggests that the treatment setting per se influences their QOL. METHOD:In a region where both treatment settings are of a comparable high standard, we assessed...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1999.tb10835.x
更新日期:1999-08-01 00:00:00
abstract:UNLABELLED:Lycanthropy is a rare psychiatric condition in which the patient believes in being transformed into an animal. Belief in the transformation of another person into an animal has not been reported, so far. Here, a patient with an impression of bipolar mood disorder (mixed type) and such delusion is reported. ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2006.00891.x
更新日期:2007-02-01 00:00:00
abstract:OBJECTIVE:In this paper we review critically the current status of neurocognitive studies in patients with chronic fatigue syndrome (CFS). METHOD:CFS literature was monitored as part of a large research project which involved several neuropsychological and psychopathological studies. The literature survey was the resu...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,评审
doi:10.1034/j.1600-0447.2001.00017.x
更新日期:2001-02-01 00:00:00
abstract:OBJECTIVE:To review the evidence from empirical studies regarding the validity of 'post-traumatic stress disorder with secondary psychotic features' (PTSD-SP) as a separate diagnostic entity. METHOD:The authors performed a review tracing publications between 1980 and January 2008. RESULTS:Twenty-four comparative stud...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0447.2008.01252.x
更新日期:2009-01-01 00:00:00
abstract::A retrospective study was made, investigating the post-treatment outcomes of patients in two apparently dissimilar psychiatric therapeutic centres in Nigeria: the Aro Mental Hospital, a custodial facility, and the Aro Community Village Program, a pilot experiment in community psychiatry. A matches sample of 208 treate...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1977.tb00135.x
更新日期:1977-01-01 00:00:00
abstract::Opinions about mental illness were measured, in 1994, in a probability sample consisting of 360 residents of two boroughs in greater Athens. These boroughs represent the catchment area of a community mental health centre. The aim of this study was to compare the differences in attitudes towards mental illness with a m...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1999.tb05387.x
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:To examine age, period and cohort effects on Australian suicide rates. METHOD:Male suicide rates for successive 5-year periods between 1919 and 1998, and for 1999 were displayed graphically to examine interactions between age, period and cohort effects. RESULTS:There has been a pronounced period effect on m...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0447.2002.1193.x
更新日期:2002-04-01 00:00:00
abstract::In a population survey in Stockholm, 224 dementia cases were staged using two scales: the Washington University Clinical Dementia Rating Scale and DSM III-R. Both scales had to be modified by adding additional specifications and, in the case of DSM III-R, a new category of questionable dementia. After modification, th...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1992.tb03225.x
更新日期:1992-07-01 00:00:00
abstract:OBJECTIVE:Exploration of academic and creative potentials of first-degree relatives of hospital-treated psychotic patients in Iceland. METHOD:Relatives identified in a previously published family study of psychosis are evaluated, using records available at the National Archives and National Library in Reykjavik. Perfo...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0447.2001.00515.x
更新日期:2001-12-01 00:00:00
abstract:OBJECTIVE:To determine the number of attempts it took before patients with a first episode of psychosis received adequate help, the signs or symptoms that led them to seek help and the people from whom they attempted to seek help. METHOD:Subjects were 86 individuals with a schizophrenia spectrum disorder, mainly schiz...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0447.2002.02004.x
更新日期:2002-11-01 00:00:00
abstract:OBJECTIVE:Research suggests that group psychotherapy for adults with a history of child sexual abuse (CSA) is generally beneficial. Only few studies have included random assignment. This study compared the effects of analytic (A) and systemic group psychotherapy (S) on CSA. METHOD:One hundred and fifty-one women with ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1600-0447.2006.00977.x
更新日期:2007-08-01 00:00:00
abstract::Fifty-eight consecutive suicides committed between 1984 and 1987 by adolescents and young adults (age 15-29 years) in an urban community were the subject of retrospective investigations by means of interviews with survivors. The outcome of the survivors' crisis reactions and the interviewees' capacity to participate i...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1991.tb05518.x
更新日期:1991-03-01 00:00:00
abstract:OBJECTIVE:To investigate the durability of positive effects of cognitive behaviour therapy (CBT) with coping training on psychotic symptoms and social functioning. METHOD:Forty patients with schizophrenia or related psychotic disorders and refractory auditory hallucinations were given CBT and coping training in an int...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0447.2001.00213.x
更新日期:2001-05-01 00:00:00
abstract::The purpose of this study was to test the transferability of the Marke-Nymann Temperament Scale (MNTS) using the Rasch item analysis. The results showed that the three Sjöbring personality dimensions Validity, Stability, and Solidity measured by the MNTS were without transferability. However, the item analysis demonst...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1978.tb06873.x
更新日期:1978-01-01 00:00:00
abstract::We studied whether regular treatment with tranquilizing and hypnotic drugs among 30,344 twins in Sweden 15-47 years old was associated with robust indicators of poor health. Longitudinal psychiatric diagnoses and subsequent suicides were analyzed with data from cross-sectional health questionnaires. Women were almost ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1990.tb03072.x
更新日期:1990-12-01 00:00:00
abstract:OBJECTIVE:This study examined the nature and determinants of predominant trajectories of posttraumatic growth (PTG) over time. METHOD:Using data from a prospective, nationally representative survey of 2718 US veterans assessed in 2011, 2013, and 2015, we used latent growth mixture modeling to identify PTG trajectories...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.12800
更新日期:2017-11-01 00:00:00