Lymph node immunohistology in intravenous drug abusers with persistent generalized lymphadenopathy.

abstract：CONTEXT:Although the value of pharmacogenomics to improve patient outcomes has become increasingly clear, adoption in medical practice has been slow, which can be attributed to several factors, including complicated and expensive testing procedures and required equipment, lack of training by private practice physicians...

journal_title：Archives of pathology & laboratory medicine

authors： Spizz G,Chen Z,Li P,McGuire IC,Klimkiewicz P,Zysling D,Yasmin R,Hungerford W,Thomas B,Wilding G,Mouchka G,Young L,Zhou P,Montagna RA

更新日期：2015-06-01 00:00:00

abstract：:Leydig cell tumor (LCT) is a rare tumor of the male testicular interstitium. This article provides an overview of the major pathologic manifestations of LCT of the testis; patient characteristics; clinical, radiologic, and laboratory features; prognosis; and management. LCTs of the testis are frequently hormonally act...

journal_title：Archives of pathology & laboratory medicine

authors： Al-Agha OM,Axiotis CA

更新日期：2007-02-01 00:00:00

abstract：:The clinical use of ionized calcium has increased since the recognition of its importance in cardiac and critical care medicine. However, more than half the general medical centers in the United States do not provide immediate testing of ionized calcium levels in patients in critical care settings, although indication...

journal_title：Archives of pathology & laboratory medicine

authors： Kost GJ

更新日期：1993-09-01 00:00:00

abstract：:We report a large cell neuroendocrine carcinoma arising in the ampulla of Vater. The patient, a 74-year-old woman, presented with a 3-cm ulcerated mass located in the ampullary region. She died of disease 8 months after surgery. Microscopically, the tumor was extensively necrotic. It was composed of islands and trabec...

journal_title：Archives of pathology & laboratory medicine

authors： Cavazza A,Gallo M,Valcavi R,De Marco L,Gardini G

更新日期：2003-02-01 00:00:00

abstract：:Congenital syphilis remains a public health concern in the United States. Infants whose mothers are treated in the third trimester without adequate prenatal care have an increased risk of morbidity and mortality in the immediate perinatal period. The identification of Treponema pallidum in tissue is definitive confirm...

journal_title：Archives of pathology & laboratory medicine

authors： Bell C,Taxy J

更新日期：2002-04-01 00:00:00

abstract：CONTEXT:Fear that damaging information from autopsy may be introduced as evidence in lawsuits alleging medical malpractice is often cited as one factor contributing to the decline in autopsy rates. OBJECTIVE:To determine how autopsy information influences the outcome of medical malpractice litigation. DESIGN:We studi...

journal_title：Archives of pathology & laboratory medicine

authors： Bove KE,Iery C,Autopsy Committee, College of American Pathologists.

更新日期：2002-09-01 00:00:00

abstract：CONTEXT:Antibody-mediated humoral rejection in kidney and heart allografts is well recognized and is often associated with poor outcome. C4d deposition in allograft biopsy specimens occurs at sites of antibody-mediated complement activation and has become one of the histopathologic criteria for diagnosis of humoral rej...

journal_title：Archives of pathology & laboratory medicine

authors： Troxell ML,Higgins JP,Kambham N

更新日期：2006-10-01 00:00:00

abstract：:This study was performed to evaluate the correlation between HER-2/neu gene expression and DNA ploidy patterns. Forty-five cases of breast-cancer were analyzed. Immunohistochemical staining of HER-2/neu protein on frozen sections was used to detect the HER-2/neu protein, and the Feulgen DNA staining method was used to...

journal_title：Archives of pathology & laboratory medicine

authors： Bacus SS,Bacus JW,Slamon DJ,Press MF

更新日期：1990-02-01 00:00:00

abstract：:Cystadenoma of the pancreas, principally a disease of adult women, was found in a female infant. This benign, nonfunctional tumor is usually amenable to surgery and a cure is to be expected after extirpation. The pathogenesis of this mass is unknown, but the finding of a cytomegalovirus infection in an excretory duct ...

journal_title：Archives of pathology & laboratory medicine

authors： Chang CH,Perrin EV,Hertzler J,Brough AJ

更新日期：1980-01-01 00:00:00

abstract：:Mucinous tubular and spindle cell carcinomas are rare kidney tumors with generally indolent behavior. As the name suggests, classic histomorphology reveals bland spindle cells, tubules, and mucinous stroma. Uncommon histologic features include mucin-poor stroma, high nuclear grade, cellular pleomorphism, and presence ...

journal_title：Archives of pathology & laboratory medicine

authors： Nathany S,Monappa V

更新日期：2020-01-01 00:00:00

abstract：:Hepatic tumors unassociated with cirrhosis were encountered in seven patients aged 10 to 19 years. Four patients had received androgens for aplastic anemia. Two patients had transfusional hemosiderosis. One patient had had a renal transplant 2 1/2 years ago. Two patients are alive at 2 3/4 and 2 1/2 years after surgic...

journal_title：Archives of pathology & laboratory medicine

authors： Chandra RS,Kapur SP,Kelleher J Jr,Luban N,Patterson K

更新日期：1984-02-01 00:00:00

abstract：:We recently encountered a unique case of follicular variant of papillary carcinoma arising in struma ovarii that contained numerous intrafollicular crystalloids. There was no evidence of capsular or vascular invasion or metastases, though the DNA content of the papillary carcinoma was aneuploid. In contrast, diploid D...

journal_title：Archives of pathology & laboratory medicine

authors： Ro JY,Sahin AA,el-Naggar AK,Ordonez NG,Mackay B,Llamas LL,Ayala AG

更新日期：1991-02-01 00:00:00

abstract：:Embolic cerebellar tissue was observed microscopically in the pulmonary and coronary arteries of a full-term male infant who died 1 hour after forceps delivery. Although embolization of brain tissue has been well documented after severe head trauma in adults and children, to our knowledge only 17 cases associated with...

journal_title：Archives of pathology & laboratory medicine

authors： Hauck AJ,Bambara JF,Edwards WD

更新日期：1990-02-01 00:00:00

abstract：:Pathologists' advocacy plays a central role in the establishment of continuously improving patient care quality and patient safety, and in the maintenance and progress of pathology as a profession. Pathology advocacy's primary goal is the betterment of patient safety and quality medical care; however, payment is a nec...

journal_title：Archives of pathology & laboratory medicine

authors： Allen TC

更新日期：2017-07-01 00:00:00

abstract：CONTEXT:Deletion of the short arm of chromosome 3 (3p deletion) is a cytogenetic abnormality generally associated with clear cell renal cell carcinoma, the most aggressive form of renal epithelial tumor. OBJECTIVE:To cytogenetically characterize 24 renal tumors in order to check the incidence and the type of 3p deleti...

journal_title：Archives of pathology & laboratory medicine

authors： Gayrard N,Cacheux V,Iborra F,Mourad G,Argilés A

更新日期：2008-06-01 00:00:00

abstract：CONTEXT:Recent advances in laboratory testing technology have resulted in a rapidly increasing number of test systems targeted for physician office, point-of-care, and home health care settings. With enhanced error detection mechanisms and unitized reagents, these new systems simplify the testing process and the assess...

journal_title：Archives of pathology & laboratory medicine

authors： LaBeau KM,Simon M,Steindel SJ

更新日期：2000-08-01 00:00:00

abstract：CONTEXT:- At our medical center, cytopathologists perform rapid on-site evaluation for specimen adequacy of fine-needle aspiration and touch imprint of needle core biopsy lung cancer samples. Two years ago the molecular diagnostics laboratory at our institution changed to next-generation sequencing using the Ion Torren...

journal_title：Archives of pathology & laboratory medicine

authors： Padmanabhan V,Steinmetz HB,Rizzo EJ,Erskine AJ,Fairbank TL,de Abreu FB,Tsongalis GJ,Tafe LJ

更新日期：2017-03-01 00:00:00

abstract：CONTEXT:Relatively little is known about estrogen receptor (ER) expression in papillary urothelial carcinoma (PUC) of the bladder. Greater understanding of this feature of PUCs could aid with the treatment and identification of the origin of metastases, particularly with relation to the morphologically similar entity o...

journal_title：Archives of pathology & laboratory medicine

authors： Croft PR,Lathrop SL,Feddersen RM,Joste NE

更新日期：2005-02-01 00:00:00

abstract：:We studied a case of Sturge-Weber syndrome in a 66-year-old woman, who displayed associated angiomas of the thyroid gland and choroid plexi and leptomeningeal melanosis. These findings are discussed in light of the proposed pathogenesis of the syndrome and its relationship to the other neuroectodermal dysplasias. ...

journal_title：Archives of pathology & laboratory medicine

authors： Bentz MS,Towfighi J,Greenwood S,Zaino R

更新日期：1982-02-01 00:00:00

abstract：OBJECTIVES:To determine the prevalence of merosin deficiency in cases of unclassified congenital muscular dystrophy and to determine the temporal stability of merosin epitopes in fixed and stored archival material. MATERIALS AND METHODS:Using an antibody to human merosin we retrospectively studied 12 cases of undiagno...

journal_title：Archives of pathology & laboratory medicine

authors： Brett FM,Loring P,Caesar A,Burke M,Brennan RP,King M,Farrell MA

更新日期：1998-01-01 00:00:00

abstract：:Pulmonary blastomas are rare primary tumors that consist of tubular or glandular structures embedded in an undifferentiated mesenchymal stroma. Focal cartilage, bone, and skeletal muscle as well as squamous differentiation have been described in these tumors. We report a unique case of a pulmonary blastoma showing a m...

journal_title：Archives of pathology & laboratory medicine

authors： Cohen RE,Weaver MG,Montenegro HD,Abdul-Karim FW

更新日期：1990-10-01 00:00:00

abstract：:Multiple pulmonary leiomyomatous hamartomas (MPLHs) are extremely rare lesions. We present a case of MPLHs associated with a bronchogenic cyst in a symptomless, 46-year-old man. Previously, MLPHs have been reported to occur in men; therefore, not all cases of MPLHs represent metastases from a uterine smooth muscle tum...

journal_title：Archives of pathology & laboratory medicine

authors： Nistal M,Hardisson D,Riestra ML

更新日期：2003-04-01 00:00:00

abstract：CONTEXT:Mutations of the proto-oncogene B-raf (BRAF) have been detected in melanocytic lesions and papillary carcinomas of the thyroid, and identification of these mutations could be useful in resolving some diagnostic problems. OBJECTIVE:To develop a method to evaluate mutations of BRAF that could provide results muc...

journal_title：Archives of pathology & laboratory medicine

authors： Hay R,MacRae E,Barber D,Khalil M,Demetrick DJ

更新日期：2007-09-01 00:00:00

abstract：:Gastric mucosal damage was produced in 130 mice by forced ingestion of alcohol, followed by restraint in the cold. Animals were killed at intervals from six hours to 27 days following the stress. Linear hemorrhagic erosions and diffuse hemorrhagic patches were found grossly, predominantly in the glandular portion of t...

journal_title：Archives of pathology & laboratory medicine

authors： Lev R,Kawashima K,Glass GB

更新日期：1976-10-01 00:00:00

abstract：:A case of primary fibrosarcoma of the urinary bladder showing extensive chondroid differentiation was studied by light microscopy and immunofluorescent microscopy using tissue-specific antibodies against intermediate filaments. The tumor cells were uniformly and positively labeled with vimentin antibodies and were neg...

journal_title：Archives of pathology & laboratory medicine

authors： Suster S,Huszar M,Bubis JJ,Geiger B

更新日期：1987-08-01 00:00:00

abstract：CONTEXT:In the 19th and early 20th centuries, cancer was defined by the demonstration of invasion and metastases, based upon gross findings at surgery or autopsy. Although histopathologic examination of tumors became possible with greater and greater resolution over time, the definition of cancer remained the same. Tum...

journal_title：Archives of pathology & laboratory medicine

authors： Wright JR Jr

更新日期：2012-11-01 00:00:00

abstract：:Values for total lactate dehydrogenase (LDH; EC 1.1.1.27) activity and LDH isoenzymes 1 and 2 were determined in 80 patients with acute myocardial infarction (AMI) and in 40 without AMI every 24 hours up to 15 days after admission, when total serum LDH level returned to normal. The sensitivity, specificity, and effici...

journal_title：Archives of pathology & laboratory medicine

authors： Rotenberg Z,Davidson E,Weinberger I,Fuchs J,Sperling O,Agmon J

更新日期：1988-09-01 00:00:00

abstract：CONTEXT.—:Breast cancer biomarker assessment is critical in determining treatment and prognosis. In Tanzania, immunohistochemistry (IHC) is limited to surgical specimens and core biopsies. However, performing IHC on fine-needle aspiration biopsy cell blocks would offer numerous advantages. OBJECTIVE.—:To compare the p...

journal_title：Archives of pathology & laboratory medicine

authors： Kimambo AH,Vuhahula EA,Mwakigonja AR,Ljung BM,Zhang L,Van Loon K,Ng DL

更新日期：2020-10-14 00:00:00

abstract：:This report describes a case of acute myeloid leukemia (subtype M1) with biphasic morphology. The bone marrow biopsy showed 2 distinct regions of blasts, one containing large cells and the other small cells. Morphometric and DNA ploidy analysis showed that the mean nuclear area and mean DNA index for the large cell re...

journal_title：Archives of pathology & laboratory medicine

authors： Imkie M,Davis MK,Persons DL,Cunningham MT

更新日期：2004-04-01 00:00:00

abstract：:Mucosa-associated lymphoid tissue (MALT) lymphomas are low-grade B-cell lymphomas that occur in a variety of extranodal sites but rarely as a primary hepatic lymphoma. We describe the histological findings, immunophenotype, and immunohistochemistry of one such lymphoma found incidentally in a 69-year-old woman. The ly...

journal_title：Archives of pathology & laboratory medicine

authors： Kirk CM,Lewin D,Lazarchick J

更新日期：1999-08-01 00:00:00