Abstract:
OBJECTIVE:The aim of this study was to investigate the clinical and pathological characteristics of uterine clear cell carcinoma (UCCC) and the treatment of this disease in relation to patient outcomes. METHODS:The clinicopathological data for and the management of all patients with UCCC who presented between 1991 and 2010 at 11 member hospitals of the Taiwanese Gynecologic Oncology Group (TGOG) were retrospectively reviewed. RESULTS:There were no significant differences in 5-year overall survival (OS) rates between patients with pure UCCC (n=100) and non-pure UCCC (n=53) at the same surgical stage, with OS rates of 92.6%, and 87.7% for stage I; 83.3% and 83.3% for stage II; 64.0% and 67.8% for stage III; and 16.7% and 0% for stage IV (n=1), respectively. Tumor stage and age independently influenced the OS rate of UCCC. For the patients with early stage UCCC, the adjuvant therapy modality was the only significant prognostic factor for recurrence-free survival. The patients with early stage UCCC who received adjuvant therapy had excellent 5-year recurrence-free survival and OS rates compared to those who received radiotherapy (100% vs. 74%, p=0.01; 100% vs. 72%, p=0.03). CONCLUSIONS:The 5-year survival rates of patients with pure UCCC and non-pure UCCC were similar. The prognosis for surgical staging of patients with stage I/II UCCC was encouraging. Postoperative adjuvant platinum-based chemotherapy is recommended for patients with early stage UCCC who are at a high risk of recurrence.
journal_name
Gynecol Oncoljournal_title
Gynecologic oncologyauthors
Hsu KF,Chou HH,Huang CY,Fu HC,Chiang AJ,Tsai HW,Chen JR,Cheng WF,Ke YM,Chang CC,Chen TH,Lin SH,Ho CMdoi
10.1016/j.ygyno.2014.07.005subject
Has Abstractpub_date
2014-09-01 00:00:00pages
516-22issue
3eissn
0090-8258issn
1095-6859pii
S0090-8258(14)01080-4journal_volume
134pub_type
杂志文章,多中心研究abstract:OBJECTIVE:To review the clinical features, diagnosis, management, and outcomes for the 50 cases of Paget's disease (PD) of the vulva referred to Queensland Centre for Gynaecological Cancer between 1986 and 2009. METHODS:Vulvar PD cases from QCGC were reviewed and analyzed using the computer software Statistical Packag...
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pub_type: 杂志文章,多中心研究
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journal_title:Gynecologic oncology
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abstract::Forty-five patients with invasive cervical squamous cell carcinoma were registered in the Tom Baker Cancer Centre from 1980 to 1985. The natural history of 22 patients (48.9%) who developed persistent or recurrent disease including 11 Stage IB, 8 Stage IIB, and 3 Stage IIIB is reported. Only one patient who had the un...
journal_title:Gynecologic oncology
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journal_title:Gynecologic oncology
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abstract:OBJECTIVE:Our goal in this article to describe our initial experience with intensity-modulated whole-pelvis radiation therapy (IM-WPRT) in gynecologic malignancies. METHODS:Between February and August 2000, 15 women with cervical (9) or endometrial (6) cancer received IM-WPRT. All patients received a treatment plannin...
journal_title:Gynecologic oncology
pub_type: 临床试验,杂志文章
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更新日期:2001-09-01 00:00:00
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journal_title:Gynecologic oncology
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pub_type: 杂志文章
doi:10.1016/j.ygyno.2005.08.039
更新日期:2006-03-01 00:00:00
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journal_title:Gynecologic oncology
pub_type: 杂志文章
doi:10.1006/gyno.1994.1147
更新日期:1994-06-01 00:00:00
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doi:10.1016/j.ygyno.2005.01.049
更新日期:2005-05-01 00:00:00
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journal_title:Gynecologic oncology
pub_type: 杂志文章,评审
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更新日期:2005-10-01 00:00:00
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journal_title:Gynecologic oncology
pub_type: 杂志文章,评审
doi:10.1016/j.ygyno.2012.04.021
更新日期:2012-09-01 00:00:00
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journal_title:Gynecologic oncology
pub_type: 杂志文章
doi:10.1016/j.ygyno.2014.01.013
更新日期:2014-04-01 00:00:00
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journal_title:Gynecologic oncology
pub_type: 杂志文章,评审
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更新日期:2014-12-01 00:00:00
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journal_title:Gynecologic oncology
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更新日期:2014-01-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:2013-11-01 00:00:00
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pub_type: 杂志文章
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更新日期:2016-05-01 00:00:00
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journal_title:Gynecologic oncology
pub_type: 杂志文章
doi:10.1016/j.ygyno.2010.11.014
更新日期:2011-04-01 00:00:00
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journal_title:Gynecologic oncology
pub_type: 杂志文章,评审
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更新日期:2018-12-01 00:00:00
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journal_title:Gynecologic oncology
pub_type: 杂志文章
doi:10.1016/j.ygyno.2012.08.013
更新日期:2012-11-01 00:00:00
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pub_type: 杂志文章
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更新日期:1984-11-01 00:00:00
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journal_title:Gynecologic oncology
pub_type: 杂志文章
doi:10.1016/j.ygyno.2005.06.065
更新日期:2006-01-01 00:00:00
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journal_title:Gynecologic oncology
pub_type: 杂志文章
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更新日期:2005-03-01 00:00:00
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journal_title:Gynecologic oncology
pub_type: 杂志文章
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更新日期:2007-01-01 00:00:00