Lymphedema and obesity: is there a link?

Abstract:

:Lymphedema is a chronic disorder that, in developed countries, occurs most commonly after lymph node dissection for cancer treatment. Although the pathophysiology of lymphedema is unknown, the disease is characterized histologically by fibrosis and abnormal adipose deposition. Clinical studies have provided evidence that obesity and postoperative weight gain are significant risk factors for the development of lymphedema. In fact, recent studies have shown that extreme obesity can result in markedly impaired lymphatic function and primary lymphedema. The aim of this Special Topic article is to review evidence linking obesity and lymphedema. In addition, the authors review recent studies that have analyzed the cellular mechanisms that may be responsible for this relationship, with a goal of highlighting areas of research that may have significant translational potential.

journal_name

Plast Reconstr Surg

authors

Mehrara BJ,Greene AK

doi

10.1097/PRS.0000000000000268

subject

Has Abstract

pub_date

2014-07-01 00:00:00

pages

154e-160e

issue

1

eissn

0032-1052

issn

1529-4242

pii

00006534-201407000-00034

journal_volume

134

pub_type

杂志文章,评审
  • Use of Roof-Shaped Costochondral Cartilage for Correction of Saddle Nose Deformity.

    abstract:BACKGROUND:Cartilage grafts are routinely used in secondary and posttraumatic rhinoplasty. However, in most cases, there are weak areas in the nasal bones and upper lateral cartilages. The purpose of this study was to seek a solution for the keystone area and dorsum of the nose in revision and posttraumatic rhinoplasty...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0000000000004459

    authors: Irmak F,Yazar SK,Sirvan SS,Yazar M,Karsidag S

    更新日期:2018-07-01 00:00:00

  • Complications of total ischiectomy for the treatment of ischial pressure sores.

    abstract::Five patients are reported, 4 of whom had total ischiectomies and the other an extensive partial ischiectomy. In each, recurrent ulcers, extending into the perineum, developed subsequently. One patient had a urethrocutaneous fistula as a result of his perineal ulcer, and he had to undergo an ileal loop diversion. Foll...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-197807000-00015

    authors: Karaca AR,Binns JH,Blumenthal FS

    更新日期:1978-07-01 00:00:00

  • Tissue oximetry monitoring in microsurgical breast reconstruction decreases flap loss and improves rate of flap salvage.

    abstract:BACKGROUND:Since the inception of microvascular free tissue transfer, flap monitoring has been based on clinical signs. Color, capillary refill, and handheld Doppler have been used for monitoring in the postoperative period; however, subjective clinical examination may delay recognition of flap compromise. Tissue oxime...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0b013e31820436cb

    authors: Lin SJ,Nguyen MD,Chen C,Colakoglu S,Curtis MS,Tobias AM,Lee BT

    更新日期:2011-03-01 00:00:00

  • The value of preoperative Doppler sonography for planning free perforator flaps.

    abstract::The individual perforating vessels have a high degree of anatomical variation, therefore it is desirable to conduct a careful examination of them before undertaking a perforator flap operation. Because locating the vessels beforehand makes performing the operative procedure much easier, the aim of the present study wa...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-200006000-00011

    authors: Giunta RE,Geisweid A,Feller AM

    更新日期:2000-06-01 00:00:00

  • The ideal nasolabial angle in rhinoplasty: a preference analysis of the general population.

    abstract:BACKGROUND:In aesthetic rhinoplasty, the described ideal nasolabial angle ranges from 90 to 120 degrees, with variable anthropologic differences. The authors sought to verify the most aesthetic nasolabial angle as specifically perceived by a random prospective sample of the general population and determine whether age,...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0000000000000385

    authors: Sinno HH,Markarian MK,Ibrahim AMS,Lin SJ

    更新日期:2014-08-01 00:00:00

  • Autologous lipofilling: coenzyme Q10 can rescue adipocytes from stress-induced apoptotic death.

    abstract:BACKGROUND:Autologous fat transplantation (or lipofilling) is an excellent technique for correction of cosmetic defects. The success of the procedure relies strongly on the techniques of harvesting and transferring viable adipocytes. The purpose of this study was to evaluate effects of two harvesting methods and coenzy...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/01.prs.0000258395.81926.d8

    authors: Witort EJ,Pattarino J,Papucci L,Schiavone N,Donnini M,Lapucci A,Lulli M,Lo Russo G,Mori A,Dini M,Capaccioli S

    更新日期:2007-04-01 00:00:00

  • The effect of cigarette smoking on the survival of free vascularized and pedicled epigastric flaps in the rat.

    abstract::Microsurgeons suspect that cigarette smoking reduces the survival of free vascularized flaps and replantations, but this has never been proven. This experimental study investigates the effect of smoking on free-flap survival. A fasciocutaneous epigastric flap was used in 30 rats as a free flap and in 30 rats as a pedi...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-199601000-00015

    authors: van Adrichem LN,Hoegen R,Hovius SE,Kort WJ,van Strik R,Vuzevski VD,van der Meulen JC

    更新日期:1996-01-01 00:00:00

  • Guiding local perforator flaps with preoperative imaging: revealing perforator anatomy to improve flap design.

    abstract:BACKGROUND:Perforator flap nomenclature continues to evolve, with many classification schemes reported. Each of them focuses on the fascial penetration pattern of perforators, which has no impact on flap perfusion. With the advent of advanced imaging technologies, the subcutaneous course of perforators can be highlight...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0b013e31824ecaff

    authors: Rozen WM,Paddle AM,Chubb D,Wilson J,Grinsell D,Ashton MW

    更新日期:2012-07-01 00:00:00

  • The free flap and plate in oromandibular reconstruction: long-term review and indications.

    abstract::The purpose of this study was to define the role of reconstruction plates as bone replacement in oromandibular reconstruction. From 1987 through 1991, 71 consecutive oral cancer patients underwent composite resection and reconstruction and were entered into one of two studies. In the first study of 31 patients, 15 und...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-199505000-00010

    authors: Boyd JB,Mulholland RS,Davidson J,Gullane PJ,Rotstein LE,Brown DH,Freeman JE,Irish JC

    更新日期:1995-05-01 00:00:00

  • Methods and results of rhinophyma treatment.

    abstract::Rhinophyma is a disfiguring soft-tissue hypertrophy of the nose. It is an uncommon disease that primarily affects Caucasian men in the fifth to seventh decades of life. Nine cases from the authors' series and a comparison of results following various treatment modalities are presented. Eight of the patients were Cauca...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-200104150-00004

    authors: Redett RJ,Manson PN,Goldberg N,Girotto J,Spence RJ

    更新日期:2001-04-15 00:00:00

  • Inframammary fold: a histologic reappraisal.

    abstract::The inframammary fold is a defining element in the shape and structure of the female breast. It should be preserved whenever possible in ablative procedures and recreated accurately when the breast is reconstructed after mastectomy. To date, no accurate anatomic description of this essential structure exists. Previous...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-200002000-00011

    authors: Muntan CD,Sundine MJ,Rink RD,Acland RD

    更新日期:2000-02-01 00:00:00

  • Reconstruction of irradiated postpneumonectomy empyema cavity with chain-link coupled microsurgical omental and TRAM flaps.

    abstract::We present the first case of complete hemithoracic reconstruction of an irradiated postpneumonectomy recurrent empyema cavity that was unresponsive to multiple conventional treatments. The procedure described used a chain-link of two coupled free flaps consisting of an omental and TRAM flap. A single abdominal donor s...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-200001000-00032

    authors: Rand RP,Maser B,Dry G,Vallieres E

    更新日期:2000-01-01 00:00:00

  • Segmental bone and cartilage reconstruction of major nasal dorsal defects.

    abstract::This article describes the results of segmental bone and cartilage reconstruction of significant nasal dorsal defects. Solid bone graft reconstructions frequently lead to an unnatural hardness of the nasal tip. Rib cartilage reconstructions are pliable and soft but are a problem because they easily undergo warpage. Th...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-200007000-00032

    authors: Neu BR

    更新日期:2000-07-01 00:00:00

  • Immediate reconstruction of full-thickness burn of an ear with an undelayed myocutaneous flap. Case report.

    abstract::We report a case in which an undelayed cervical myocutaneous flap was used early to cover the denuded cartilage of a burned ear. The ear was saved, and a good result was obtained. ...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-197810000-00030

    authors: McGrath MH,Ariyan S

    更新日期:1978-10-01 00:00:00

  • Practical management of congenital choanal atresia.

    abstract::Prevailing theories on the causation of choanal atresia are presented, with emphasis on some of the embryologic and anatomic abnormalities that are consistently found. The teleologic significance of nose breathing has been emphasized. This neonatal characteristic leads to a tongue-palate seal that can be rapidly fatal...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-198311000-00007

    authors: Theogaraj SD,Hoehn JG,Hagan KF

    更新日期:1983-11-01 00:00:00

  • Biology and Biomarkers for Wound Healing.

    abstract:BACKGROUND:As the population grows older, the incidence and prevalence of conditions that lead to a predisposition for poor wound healing also increase. Ultimately, this increase in nonhealing wounds has led to significant morbidity and mortality with subsequent huge economic ramifications. Therefore, understanding spe...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章,评审

    doi:10.1097/PRS.0000000000002682

    authors: Lindley LE,Stojadinovic O,Pastar I,Tomic-Canic M

    更新日期:2016-09-01 00:00:00

  • Comparison of free and reversed pedicled posterior interosseous cutaneous flaps.

    abstract::The posterior interosseous cutaneous flap is characterized by its thinness and the adjustable length of its vascular pedicle. This flap can be used both as a free and reversed vascular pedicled flap. We applied the free flap mostly for reconstruction of the digits, and the reversed vascular pedicled flap for soft-tiss...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-199703000-00028

    authors: Shibata M,Iwabuchi Y,Kubota S,Matsuzaki H

    更新日期:1997-03-01 00:00:00

  • Improved survival of island flaps after prolonged ischemia by perfusion with superoxide dismutase.

    abstract::Perfusion of rat groin flaps after 10 and 11 hours of complete ischemia with superoxide dismutase, an oxygen free-radical scavenger, significantly improved the survival of these flaps. This finding provides further evidence for the important role that oxygen-derived free radicals play in ischemic injury. The study als...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-198604000-00022

    authors: Sagi A,Ferder M,Levens D,Strauch B

    更新日期:1986-04-01 00:00:00

  • Reconstruction of the burned nipple-areola complex.

    abstract::Reconstructive results of 115 burned nipple-areola complexes in 84 female patients were reviewed. Results of nipple reconstruction using local quadrapod flaps (33 percent good, 45 percent fair, 22 percent poor) and composition grafts from the earlobe (20 percent good, 60 percent fair, 20 percent poor) were comparable,...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-198610000-00007

    authors: Pensler JM,Haab RL,Parry SW

    更新日期:1986-10-01 00:00:00

  • Incidence of cleft palate fistula: an institutional experience with two-stage palatal repair.

    abstract::The purpose of this study was to determine the incidence of cleft palatal fistula in a series of nonsyndromic children treated at the authors' institution. This retrospective analysis of 103 patients with cleft palate treated by five surgeons between 1982 and 1995 includes 60 boys and 33 girls, whose median age was 18...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-200111000-00011

    authors: Muzaffar AR,Byrd HS,Rohrich RJ,Johns DF,LeBlanc D,Beran SJ,Anderson C,Papaioannou aA A

    更新日期:2001-11-01 00:00:00

  • Quantitative analysis of blood and fat in suction lipectomy aspirates.

    abstract::This study of suction lipectomy aspirates from 15 consecutive patients was undertaken to biochemically quantitate the blood-to-fat ratios of the aspirates. A wide variation in the blood-to-fat ratios (8 to 54 percent) was noted, but the authors failed to demonstrate any relationship between the blood-to-fat ratios and...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-198678060-00009

    authors: Goodpasture JC,Bunkis J

    更新日期:1986-12-01 00:00:00

  • The effects of combined cooling and perfusion on experimental free-flap survival in rabbits.

    abstract::The viability of the rabbit epigastric flap was investigated after a period of cold ischemia of 3, 4, or 5 days. Groups of flaps were either perfused with Ross's solution before ischemia (early perfusion), after ischemia (late perfusion), or not at all (control). Significantly more flap necrosis was formed at explorat...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-198507000-00017

    authors: Gould JS,Sully L,O'Brien BM,Das SK,Knight KR,Hurley JV

    更新日期:1985-07-01 00:00:00

  • Patient satisfaction in postmastectomy breast reconstruction: a comparative evaluation of DIEP, TRAM, latissimus flap, and implant techniques.

    abstract:BACKGROUND:Despite a growing literature on patient satisfaction in breast reconstruction, few studies have compared perforator flaps with the more commonly practiced methods. The authors compared four reconstructive techniques and identified factors influencing patient satisfaction. METHODS:All patients undergoing pos...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0b013e3181cb6351

    authors: Yueh JH,Slavin SA,Adesiyun T,Nyame TT,Gautam S,Morris DJ,Tobias AM,Lee BT

    更新日期:2010-06-01 00:00:00

  • Superior results using the islandized hemipalatal flap in palatoplasty: experience with 500 cases.

    abstract:BACKGROUND:The double-opposing Z-plasty palatal repair, as reported by Dr. Furlow, is one of the most popular methods of primary cleft palate repair. However, the repair as originally described is difficult to perform on wide palatal clefts. The authors have modified the original repair by altering the hard palatal fla...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0b013e31817741e8

    authors: Bindingnavele VK,Bresnick SD,Urata MM,Huang G,Leland HA,Wong D,Hammoudeh J,Reinisch J

    更新日期:2008-07-01 00:00:00

  • Electrolyte and plasma enzyme analyses during large-volume liposuction.

    abstract::Substantial fluid shifts occur during liposuction as wetting solution is infiltrated subcutaneously and fat is evacuated, causing potential electrolyte imbalances. In the porcine model for large-volume liposuction, plasma aspartate aminotransferase and alanine transaminase levels were elevated following liposuction. T...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/01.prs.0000131022.98481.6e

    authors: Lipschitz AH,Kenkel JM,Luby M,Sorokin E,Rohrich RJ,Brown SA

    更新日期:2004-09-01 00:00:00

  • Practical Tips to Improve Efficiency and Success in Upper Limb Replantation.

    abstract:LEARNING OBJECTIVES:After reading this article, participant should be able to: 1. Describe the technique of replantation for very distal amputation of the digit and salvage procedures for venous drainage. 2. Perform single-digit replantation after viewing the videos. 3. Recognize appropriate cases for joint salvage tec...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章,评审

    doi:10.1097/PRS.0000000000006134

    authors: Woo SH

    更新日期:2019-11-01 00:00:00

  • Facial Contour Symmetry Outcomes after Site-Specific Facial Fat Compartment Augmentation with Fat Grafting in Facial Deformities.

    abstract:BACKGROUND:The purposes of this study were to evaluate facial symmetry after the first fat grafting session in patients with unilateral facial contour deformities and to identify independent predictors of 12-month postoperative facial symmetry. METHODS:A prospective analysis was conducted of consecutive patients (n = ...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0000000000005220

    authors: Denadai R,Buzzo CL,Raposo-Amaral CA,Raposo-Amaral CE

    更新日期:2019-02-01 00:00:00

  • The Addition of Platelet-Rich Plasma to Facial Lipofilling: A Double-Blind, Placebo-Controlled, Randomized Trial.

    abstract:BACKGROUND:Lipofilling is a treatment modality to restore tissue volume, but it may also rejuvenate the aging skin. Platelet-rich plasma has been reported to augment the efficacy of lipofilling, both on graft take and rejuvenation, by altering the adipose-derived stem cells. The authors hypothesized that addition of pl...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/PRS.0000000000004081

    authors: Willemsen JCN,Van Dongen J,Spiekman M,Vermeulen KM,Harmsen MC,van der Lei B,Stevens HPJ

    更新日期:2018-02-01 00:00:00

  • Cranioplasty in the growing canine skull using demineralized perforated bone.

    abstract::This study was designed to test the hypothesis that demineralized perforated bone matrix implant from canine skull and tibia induces new bone formation within the calvarial defect comparable with the bone induced by autogenous graft. We also were interested in determining whether demineralized perforated bone matrix i...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-199509001-00002

    authors: Salyer KE,Bardach J,Squier CA,Gendler E,Kelly KM

    更新日期:1995-09-01 00:00:00

  • Live demonstration of microcirculation in the deep fascia and its implication.

    abstract::The rich vascular network in the deep fascia has been emphasized by various scientists, but the actual demonstration of live circulation in the deep fascia has not previously been witnessed. Encouraged by the sight of live circulation in the web membrane of toad hind limb, a successful attempt was made to demonstrate ...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/01.prs.0000150143.76552.21

    authors: Bhattacharya V,Watts RK,Reddy GR

    更新日期:2005-02-01 00:00:00