The effects of combined cooling and perfusion on experimental free-flap survival in rabbits.

Abstract:

:The viability of the rabbit epigastric flap was investigated after a period of cold ischemia of 3, 4, or 5 days. Groups of flaps were either perfused with Ross's solution before ischemia (early perfusion), after ischemia (late perfusion), or not at all (control). Significantly more flap necrosis was formed at exploration 7 days after revascularization in the early perfusion group than in the control group (p less than 0.01). Late perfusion was not significantly detrimental to flap survival as compared with cold storage alone (0.1 less than p less than 0.5). It is concluded that early perfusion is detrimental to the ultimate fate of the cold ischemic flap, whereas late perfusion offers no advantage over cold storage alone.

journal_name

Plast Reconstr Surg

authors

Gould JS,Sully L,O'Brien BM,Das SK,Knight KR,Hurley JV

doi

10.1097/00006534-198507000-00017

subject

Has Abstract

pub_date

1985-07-01 00:00:00

pages

104-9

issue

1

eissn

0032-1052

issn

1529-4242

journal_volume

76

pub_type

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