Abstract：
:Thyroid cancer is the most common endocrine malignancy and its incidence has increased over the past few decades. Most patients with thyroid cancer have an excellent prognosis, but there is a 15% recurrence rate within 10 years after initial treatment and mortality is possible. To date, there are no prospective, well-defined data supporting the use of molecular markers alone to decide the extent of treatment of patients with thyroid cancer or to predict the individual prognosis of these patients. Molecular markers are promising in the development of new targeted therapies particularly for radioiodine-refractory and unresectable thyroid cancers.
journal_name
Otolaryngol Clin North Amjournal_title
Otolaryngologic clinics of North Americaauthors
Ozgursoy OB,Eisele DW,Tufano RPdoi
10.1016/j.otc.2014.04.010subject
Has Abstractpub_date
2014-08-01 00:00:00pages
595-607issue
4eissn
0030-6665issn
1557-8259pii
S0030-6665(14)00036-Xjournal_volume
47pub_type
杂志文章,评审abstract：:Diet hypersensitivity may be "allergic," that is, caused by some form of immunologic reaction, or nonallergic. The latter includes chemical pharmacologic, enzymatic, or dietary disorders. Food allergies may be immediate Gell and Coombs type I reactions (5%), or delayed "serum sickness" type reactions (95%). The latter...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1992-02-01 00:00:00
abstract：:Patients with dizziness and psychopathology present diagnostic and therapeutic challenges to clinicians in several specialties. Clinical research is beginning to define the medical-psychiatric interactions that produce many of these patients' symptoms. Treatment research is still in its infancy. A model of illness pro...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0030-6665(05)70230-9
更新日期：2000-06-01 00:00:00
abstract：:Craniofacial disassembly now plays a major role in the management of tumors that invade the skull base. The chief advantage of this technique is the greatly improved operative exposure it provides, allowing the surgeon to resect such tumors more completely and with an added margin of safety. Microneurosurgical advance...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1991-12-01 00:00:00
abstract：:This article reviews the evolution of the author's stapedectomy technique from total footplate removal with single loop wire prosthesis and Gelfoam seal to small fenestra stapedectomy with platinum ribbon piston prosthesis and blood seal. The author concludes that the microdrill is effective, safe, and cost effective ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1993-06-01 00:00:00
abstract：:Since the description of a transnasal approach for treatment of pituitary tumors, transsphenoidal surgery has undergone continuous development. Hirsch developed a lateral endonasal approach before simplifying it to a transseptal approach. Cushing approached pituitary tumors using a transsphenoidal approach but transit...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2015.09.005
更新日期：2016-02-01 00:00:00
abstract：:Our experience has revealed the following: (1) TRT is applicable for all types of tinnitus, as well as for decreased sound tolerance, with significant improvement of tinnitus occurring in over 80% of the cases, and at least equal success rate for decreased sound tolerance. (2) TRT can provide cure for decreased sound ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0030-6665(02)00172-x
更新日期：2003-04-01 00:00:00
abstract：:Cross-sectional imaging plays an important role in the evaluation of the retropharyngeal space (RPS) and the prevertebral space (PVS). Because of their deep location within the neck, lesions arising within these spaces are difficult, if not impossible, to evaluate on clinical examination. This article details the cros...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2012.08.004
更新日期：2012-12-01 00:00:00
abstract：:Painful disease processes that affect the mucous membranes of the upper aerodigestive tract include viral and bacterial infections, hypersensitivity reactions, and immunopathologic disorders. The diagnosis and treatment of the most common diseases that cause pain are described. ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1989-12-01 00:00:00
abstract：UNLABELLED:1. Do not create an emergency obstruction unless you are prepared to handle it. (It may be best to do nothing until the diagnosis is clear.) 2. Support the patient with oxygen, humidity, and positioning and monitor vital signs. 3. Take as brief, concise, and accurate a history as possible. 4. Determine the a...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1979-05-01 00:00:00
abstract：:The larynx is a highly vascularized organ supplied by the superior and inferior laryngeal arteries. Both microphonosurgery and external laryngeal surgery require excellent hemostasis. Topical agents including adrenalin and fibrin-based products as well as surgical instrumentation, such as coagulation devices or in som...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2016.03.009
更新日期：2016-06-01 00:00:00
abstract：:Cholesteatomas (epidermoids) of the middle ear appearing medial to a normal tympanic membrane are identified in increasing numbers of young children. The evidence that these lesions are congenital in origin includes the young mean age of presentation, the normal appearance of the middle ear mucosa in almost all cases ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1989-10-01 00:00:00
abstract：:Over the years, a variety of empirical regimens have evolved using intratympanic gentamicin to treat the vertigo associated with Meniere's disease. Although these regimens have been effective, their application is not without risk. Many of the problems associated with intratympanic medications could be overcome with t...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1997-12-01 00:00:00
abstract：:The medical community is no exception when it comes to structural racism and implicit bias, often present in dangerously subtle ways. To enter a residency program in which one is the only black person seems odd, especially considering the decades-long calls to action for increasing diversity. Unless the societal major...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2020.09.018
更新日期：2021-02-01 00:00:00
abstract：:Active auditory implants, such as the Maxum, provide significantly improved hearing function compared to hearing aids in patients with moderate to severe hearing loss who are not reaching their cochlear hearing potential. The speech perception gap (SPG), defined as PB Max (phonetically balanced maximum) minus word rec...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2018.11.014
更新日期：2019-04-01 00:00:00
abstract：:Primary, secondary, and tertiary hyperparathyroidism have evolved since their original description. What was once a debilitating disease has now become one with few symptoms on initial presentation. Complications from these disorders have decreased significantly because of earlier detection. Improved management of pat...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2004.02.004
更新日期：2004-08-01 00:00:00
abstract：:Despite being introduced in the 1970s and 1980s, CT and MRI continue to be the primary imaging modalities for the temporal bone and skull base. Although the general concepts and physics remain the same, the images obtained currently are far superior. Augmenting these traditional modalities are nuclear medicine imaging...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2007.03.001
更新日期：2007-06-01 00:00:00
abstract：:The results of this study and others document the biologic behavior of acoustic neuromas. In view of the evidence presented, which describes both variable rates of individual tumor growth and spontaneous regression in size, it would seem prudent that before selecting a nonsurgical treatment modality, the growth rate f...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1992-06-01 00:00:00
abstract：:Meniere's disease can be observed uniquely in revisions of the conservative surgical procedure for endolymphatic sac enhancement, which preserves the labyrinth, unlike destructive procedures. Genetic anatomic abnormalities in patients lead to malabsorption of endolymph and symptoms of Meniere's that are reversed by en...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2006.03.001
更新日期：2006-08-01 00:00:00
abstract：:After nearly a century of performing thyroidectomy essentially the way it was described by Theodore Kocher in the nineteenth century, the technique has quickly evolved. Parathyroidectomy has advanced as biochemical assays and physiologic imaging have become available. Minimally invasive and endoscopic thyroidectomy an...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2010.02.005
更新日期：2010-04-01 00:00:00
abstract：:Neuromuscular retraining is an effective method for rehabilitating facial musculature in patients with facial paralysis. This nonsurgical therapy has demonstrated improved functional outcomes and is an important adjunct to surgical treatment for restoring facial movement. Treatment begins with an intensive clinical ev...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1997-10-01 00:00:00
abstract：:There have been many advances in microsurgery for voice professionals over the last three decades. Driven by a greater understanding of the anatomy and physiology of phonation, most of the advances provide greater surgical precision through improved exposure and more delicate instrumentation. Laryngologists who perfor...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2007.05.015
更新日期：2007-10-01 00:00:00
abstract：:We review the therapies for primary headache disorders: migraine, chronic migraine, tension-type headache, and cluster headache. Recommendations follow the evidence-based treatments so far as is possible with expert opinion to give clinical guidance. Headache has 2 levels of care: acute treatments designed to stop a h...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2013.11.002
更新日期：2014-04-01 00:00:00
abstract：:Chronic daily headache (CDH) refers to the daily or almost daily occurrence of headache for a prolonged period of time, with lack of a well-defined attack pattern. It constitutes the vast majority of daily headaches. Hemicrania continua, a condition that closely resembles CDH, will be discussed as part of this article...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0030-6665(03)00133-6
更新日期：2003-12-01 00:00:00
abstract：:The management of major airway collapse in the pediatric age group has evolved and continues to evolve over time. Tracheobronchomalacia, either primary or secondary, is still the most frequent cause of major airway collapse. This article reviews tracheobronchomalacia and discusses several treatment options; from tradi...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0030-6665(05)70213-9
更新日期：2000-02-01 00:00:00
abstract：:Gastroesophageal reflux (GER) may have a role in upper airway disease such as chronic sinusitis and pharyngolaryngitis. Methods of assessment of reflux, although never absolute, are useful in selecting GER as a component in the induction of upper respiratory disease. Patients with intractable sinusitis and otitis have...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1996-02-01 00:00:00
abstract：:Lateral rhinotomy and medial maxillectomy have evolved in the last 25 years as the treatment of choice for most neoplastic lesions involving the lateral nasal wall. Technical refinements have allowed this procedure to be performed with acceptable and minimal morbidity. This approach has had its widest application in t...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1995-12-01 00:00:00
abstract：:Gastroesophageal reflux disease (GERD) contributes to the development of many otolaryngologic symptoms and conditions, including chronic throat clearing, cough, sore throat, contact ulcer and granuloma, globus pharyngeus, cervical dysphagia, cancer of the larynx, subglottic stenosis, and cricoarytenoid arthritis. Thes...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1991-10-01 00:00:00
abstract：:Osseointegrated auditory devices (OADs) are hearing devices that use an external receiver/processor that stimulates bone conduction of sound via a titanium prosthesis that is drilled into the bone of the cranium. Since their introduction in 1977, OADs have undergone substantial evolution, including changes in manufact...
journal_title：Otolaryngologic clinics of North America
pub_type： 历史文章,杂志文章,评审
doi：10.1016/j.otc.2018.11.005
更新日期：2019-04-01 00:00:00
abstract：:The preferred antibiotic treatment for tonsillar and peritonsillar infections remains high dosages of penicillin. Peritonsillar swelling can be probed by needle aspiration. Where necessary, immediate incision and drainage of an abscess can be achieved. Quinsy tonsillectomy may be carried out for the best abscess expos...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1987-05-01 00:00:00
abstract：:Endoscopic endonasal approaches to the skull base pathology have developed and evolved dramatically over the past 2 decades, particularly with collaboration between neurosurgery and otolaryngology physicians. These advances have increased significantly the use of such approaches beyond just resection of pituitary aden...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2015.09.014
更新日期：2016-02-01 00:00:00
