Breast Implant-Associated Bilateral B-Cell Lymphoma.

Abstract:

:Lymphomas associated with implants are predominantly of T-cell type-with anaplastic large cell lymphoma (ALCL) being most reported. That said, to date, 6 cases of B-cell lymphoma associated with breast implants have been reported. All cases exhibited unilateral breast involvement. Here, the authors report a case of low-grade B-cell lymphoma occurring bilaterally in a 34-year-old woman with a history of Poly Implant Prosthese silicone implants at age 20, T-cell angioimmunoblastic lymphoma, and subsequent myeloablative double cord blood transplantation. Lymphoma cells were positive for CD20, CD5, BCL-2, CD21, CD23, IgD, IgM, with very low Ki-67 of 1%. Nevertheless, cases of ALCL associated with breast implants are rare but much more documented in the literature than B-cell lymphomas associated with breast implants, as in this patient. Identification of a relationship between breast cancer and silicone is still ongoing in the literature, with long-term clinical follow up required. More research will be necessary to fully characterize the occurrence, course, and association of this disease with breast implants in order to properly guide diagnosis and management. LEVEL OF EVIDENCE: 5:

journal_name

Aesthet Surg J

authors

Chen VW,Hoang D,Clancy S

doi

10.1093/asj/sjy093

subject

Has Abstract

pub_date

2020-01-29 00:00:00

pages

NP52-NP58

issue

2

eissn

1090-820X

issn

1527-330X

pii

4964805

journal_volume

40

pub_type

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