Abstract:
BACKGROUND:Hyperalgesia, defined as hypersensitivity to pain, refers to sensitization of nociceptors to normal levels of pain. OBJECTIVES:We aimed to determine whether hyperalgesia occurs due to the development of sensitization following repeated applications of platelet-rich plasma (PRP), and to ascertain the mechanism responsible for inducing hyperalgesia. METHODS:This study, performed between 2016 and 2017, involved 32 rats. A 2 cm × 2 cm area was shaved on the back of 10 experimental and 10 sham control animals. In the experimental animals this area was divided into 4 equal squares of 1 cm × 1 cm, and these squares were numbered 1 (no treatment; only the needle was inserted), 2 (0.2 mL, saline), 3 (0.2 mL, nonactivated PRP), and 4 (0.2 mL, activated PRP). The response of the animals to painful stimuli in these areas was investigated with Von Frey filaments, immediately before application and 4 weeks after the last application. Skin biopsies were taken, and growth factors were evaluated pathologically and biochemically. RESULTS:Hyperalgesia developed in all 4 areas of each experimental rat but not in the sham group. However, areas 3 and 4 had smaller Von Frey g values than areas 1 and 2. When growth hormones were assessed histopathologically and biochemically, nerve growth factor (NGF) levels were found to be higher in areas 3 and 4 than in areas 1 and 2 and the sham group. CONCLUSIONS:Both nonactivated and activated PRP resulted in greater hypersensitivity than saline and sham treatment. Development of hyperalgesia may be associated with an increase in NGF as well as increased inflammatory mediators.
journal_name
Aesthet Surg Jjournal_title
Aesthetic surgery journalauthors
Ince B,Yıldırım MEC,Kilinc I,Oltulu P,Dadaci Mdoi
10.1093/asj/sjz113subject
Has Abstractpub_date
2019-09-13 00:00:00pages
1139-1145issue
10eissn
1090-820Xissn
1527-330Xpii
5445341journal_volume
39pub_type
杂志文章abstract:BACKGROUND:A preliminary report on a new technique for dermal overlap subareolar mastopexy appeared in 2001. OBJECTIVE:This paper reports on a series of 117 patients who underwent subareolar mastopexy and describes several modifications of the original technique. METHODS:Preoperative markings defined the upper edge o...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1016/S1090-820X(03)00205-X
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND:The ears increase in all dimensions over the years (eg, length, helix diameter, lobe length), but the most obvious change is the elongation or ptosis of the lobe. Its correction should be considered a part of facial rejuvenation. OBJECTIVES:The authors presented the surgical procedure they have been utilizi...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjz348
更新日期:2020-07-13 00:00:00
abstract:BACKGROUND:It would be useful if existing tools or outcomes measures could predict which patients are at greater risk of revision surgery following rhinoplasty. OBJECTIVE:We aim to determine if a single question assessing nasal self-esteem could be used to predict which patients are at greatest risk of revision surger...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjaa252
更新日期:2020-08-28 00:00:00
abstract::With continuous technical and functional advances in the field of breast reconstruction, there is now a greater focus on the artistry and aesthetic aspects of autologous reconstruction. Whereas once surgeons were most concerned with flap survival and vessel patency, they are now dedicated to reconstructing a similarly...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjaa223
更新日期:2020-11-17 00:00:00
abstract:BACKGROUND:Diced cartilage is a valuable material that has recently been added to the graft options in rhinoplasty. Shaping, fixation, and resorption are the main concerns with this material. Perichondrially attached diced conchal cartilage may be a new possibility to solve some of these problems. OBJECTIVES:The autho...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X12455635
更新日期:2012-09-01 00:00:00
abstract:Background:The perioral region is the most dynamic anatomic area of the face and subject to complex and dramatic changes during aging. Successful treatment for perioral rejuvenation has yet to be identified, and prior studies have reported only subjective outcomes. Objectives:The purpose of this study was to utilize o...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjy060
更新日期:2018-10-15 00:00:00
abstract::Posterior neck lift, which combines anterior platysmaplasty and anterior and lateral neck lift, is a good alternative to a full or lower face lift for patients with minimal or no jowl sagging. It may be combined with neck lipoplasty, serial platysma notching, expanded polytetrafluoroethylene neck sling, and chemical p...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1016/j.asj.2004.01.005
更新日期:2004-03-01 00:00:00
abstract:BACKGROUND:To obtain an ideal outcome in breast augmentation procedures, breast implants may be overfilled to reduce wrinkles and improve longevity. Determination of the optimal volume for saline-filled breast implants remains problematic for plastic surgeons. OBJECTIVE:We sought to evaluate the effect of overfilling ...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1016/j.asj.2005.11.003
更新日期:2006-01-01 00:00:00
abstract::Volume enhancement/restoration addresses a key component of facial aging and plays an increasingly central role in facial rejuvenation. Advancing our understanding of the structure and morphology of facial aging-and the changes that can be induced with currently-available fillers-will optimize treatment and provide a ...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X11434523
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:Nanofats could improve photoaging. Stromal vascular fraction (SVF) and adipose-derived stem cells (ADSCs) may play pivotal roles. However, SVFs and ADSCs in nanofats processed by conventional methods cannot be enriched. Some researchers have found that after centrifugation, the SVF/ADSC density increases fro...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjz066
更新日期:2019-10-15 00:00:00
abstract::The primary goal of palatoplasty is to allow normal speech through the correction of velopharyngeal incompetence. Failure to accomplish a tension-free, watertight closure predisposes the palatoplasty patient to postoperative fistula formation. Fistulas may in turn contribute to velopharyngeal incompetence. Reported fi...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,评审
doi:10.1177/1090820X11418216
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Tranexamic acid (TXA) is an antifibrinolytic agent shown to decrease intraoperative bleeding, reduce transfusions, and improve outcomes across multiple specialties. Within plastic surgery, initial reports are encouraging but formal studies are lacking. OBJECTIVES:The aim of this study was to determine wheth...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjaa072
更新日期:2021-01-25 00:00:00
abstract:BACKGROUND:Free tissue transfer with lower abdominal flaps for autologous breast reconstruction is not suitable for all patients. The latissimus dorsi (LD) musculocutaneous flap is an alternative, effective method for both immediate and delayed breast reconstruction. OBJECTIVES:The authors assess their experience with...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X12437783
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:Patient Reported Outcome Measures (PROM) are increasingly used in healthcare to assess outcomes. The BREAST-Q Implant Surveillance (BREAST-Q IS) is a 5-question Patient Reported Outcome Measure (PROM) used by the Australian Breast Device Registry (ABDR) to monitor the performance of breast devices. Validatio...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjaa342
更新日期:2020-12-08 00:00:00
abstract:BACKGROUND:Safety and efficacy of botulinum toxin A for glabellar line (GL) treatment are well established. Currently approved formulations require reconstitution before injection. OBJECTIVES:The authors sought to assess 6-month efficacy, safety, and patient satisfaction of new ready-to-use abobotulinumtoxinA solution...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,随机对照试验
doi:10.1093/asj/sjz003
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:The size and weight of hypertrophied breast can cause both physical and psychological problems. Although the majority of these problems can be solved with breast reduction surgery, the particular problem of development of brassiere strap grooves on the shoulders due to the weight of the breasts cannot be cor...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjv007
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Rhinoplasty in the elderly requires different surgical approaches due to the morphological and structural changes affecting the nose over time. OBJECTIVES:In this study, the authors aimed to evaluate the age-related cellular and architectural changes of nasal cartilages and soft tissue attachments. METHODS...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjy245
更新日期:2019-08-22 00:00:00
abstract:BACKGROUND:The American Society for Aesthetic Plastic Surgery (ASAPS) sponsors an annual conference that promotes education, advocacy, and care. There, researchers deliver abstracts as podium and poster presentations. Subsequently, ASAPS encourages submitting these research findings for publication. Yet, many never bec...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjw097
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Liposuction is one of the most common aesthetic procedures and a number of options are available to practitioners in terms of surgical technique. One of those options is ultrasound-assisted liposuction (UAL), which has garnered considerable attention in the literature and from patients themselves. Because th...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X10378086
更新日期:2010-09-01 00:00:00
abstract::Fat grafting is a common procedure in aesthetic and reconstructive plastic surgery, but variable graft retention limits its utility. Unpredictable clinical outcomes with fat grafting can be explained in part by the lack of standardized protocols for harvesting, processing, and transplanting adipose tissue (AT). Histor...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,评审
doi:10.1093/asj/sju059
更新日期:2015-02-01 00:00:00
abstract::As injectable products have been introduced and as clinicians have gained experience with them, applications and techniques for injection have evolved, with better cosmetic results, enhanced patient safety, and greatly improved patient satisfaction. Within the past four years, several consensus recommendation panels h...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X10378697
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND:A significant proportion of patients seeking labiaplasty are nulliparous and may experience later changes to their labia following vaginal delivery. OBJECTIVES:In the present study, we report the long-term outcomes of a single surgeon's patient cohort who had vaginal delivery after labiaplasty. METHODS:A r...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjaa027
更新日期:2020-01-29 00:00:00
abstract:BACKGROUND:With the demand for cosmetic surgery continuing to rise, it is necessary to reevaluate the current state of cosmetic surgery training during plastic surgery residency. An evaluation of cosmetic surgery training in US plastic surgery residency programs in 2006 identified several areas for improvement, resulti...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X12467794
更新日期:2013-01-01 00:00:00
abstract::Injectable synthetic hyaluronic acid is biodegradable and biocompatible with human hyaluronic acid. Soft tissue augmentation with this product does not require prior skin testing and provides robust augmentation. Its ability to attract and maintain significant amounts of water accounts for the volume and duration of c...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1016/j.asj.2004.04.009
更新日期:2004-07-01 00:00:00
abstract::Guidelines issued by the American Society for Aesthetic Plastic Surgery and other professional organizations have helped to reduce complications associated with lipoplasty. However, current guidelines for lipoplasty do not address the issue of hypothermia, which can be aggravated by infiltration of large amounts of an...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1067/maj.2001.113439
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:Regardless of the technique chosen to treat the aging midface, the isolated lateral approach facelift has a limited impact on the midface volume deficit. In an effort to overcome this limitation, modern facial rejuvenation procedures incorporate an additional modality for replenishing the midface volume. Som...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjz129
更新日期:2020-03-23 00:00:00
abstract:Background:Low satisfaction rates and severe complications are two major limitations for temporal hollowing augmentation using autologous fat grafting. Despite fat compartments in temporal region have been reported, its clinical applied anatomy for fat grafting have not been the subject of studies that show its benefit...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjw257
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Lips are considered a key element of facial attractiveness due to their central position in the face and their elemental role in verbal and nonverbal communication. OBJECTIVES:The authors sought to provide clinically relevant information on the 3-dimensional pathway of the superior and inferior labial arter...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjaa137
更新日期:2020-11-19 00:00:00
abstract:BACKGROUND:The efficacy of adipose-derived stem cells (ASCs) to improve wound healing has been extensively investigated. Unfortunately, no consistent reports have described significant improvements in healing time or outcomes in large-scale clinical trials utilizing human ASCs. Primarily, these studies examined undiffe...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjz071
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Until 2001, body contouring surgery after massive weight loss was uncoordinated, with few patients achieving compete rehabilitation. OBJECTIVE:The authors report a 5-year, retrospective, 75-case clinical review to determine the effectiveness, reliability, and safety of single and multistage total body lift ...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1016/j.asj.2008.03.001
更新日期:2008-05-01 00:00:00