Abstract:
BACKGROUND:The characteristics of patients with co-occurring chronic pain and prescription opioid abuse have not been well described, and even less is known about differences between men and women in this population. OBJECTIVES:This study evaluated sex differences in the demographic, diagnostic, and behavioral attributes of patients with chronic pain and opioid abuse. METHODS:Data were collected via self-report and semistructured clinical interviews from 162 patients (120 men and 42 women) who screened for a study investigating the abuse liability of prescription opioids. RESULTS:There were no differences between men and women in age, race, education, marital status, or employment status. Participants had used prescription opioids for 5.4 ± 6.7 years. The majority of participants (60%) had low back pain in addition to opioid dependence as defined by the Diagnostic and Statistical Manual of Mental Disorders Fourth Edition. More women reported more arthritic pain than men, but otherwise there were no differences in types of pain. Pain exerted a greater effect in women on mood, walking ability, and social relations. Men reported more of certain aberrant behaviors, including abuse of alcohol or illicit drugs, unauthorized dose increases, contact with street culture, and being arrested by police. Women were more depressed than men. CONCLUSIONS:The demographic profile of opioid-abusing patients with chronic pain presenting for treatment in a clinical trial was similar between sexes; however, some important differences were observed. Women reported more psychiatric comorbidity and endorsed greater pain-related physical and social impairment. Men reported more aberrant behaviors. These differences suggest that men with chronic pain and opioid abuse/dependence may benefit by closer monitoring of aberrant behaviors whereas women may benefit from closer attention paid to physical and psychological effects of pain.
journal_name
J Addict Medjournal_title
Journal of addiction medicineauthors
Manubay J,Davidson J,Vosburg S,Jones J,Comer S,Sullivan Mdoi
10.1097/ADM.0000000000000086subject
Has Abstractpub_date
2015-01-01 00:00:00pages
46-52issue
1eissn
1932-0620issn
1935-3227journal_volume
9pub_type
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journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0b013e3181e8b6c4
更新日期:2011-06-01 00:00:00
abstract:AIM:This study has 2 aims. Firstly, we explore and analyze the associations between physicians' unhealthy substance use and various work-cultural and social aspects; secondly, we describe how substance use disorder (SUD defined as by Alcohol Use Disorders Identification Test [AUDIT] and Drug Use Disorders Identificatio...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000228
更新日期:2016-07-01 00:00:00
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journal_title:Journal of addiction medicine
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doi:10.1097/ADM.0000000000000020
更新日期:2014-05-01 00:00:00
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journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000112
更新日期:2015-05-01 00:00:00
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journal_title:Journal of addiction medicine
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更新日期:2020-08-18 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2019-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1097/ADM.0000000000000384
更新日期:2018-03-01 00:00:00
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journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0b013e31818ebb6f
更新日期:2009-09-01 00:00:00
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更新日期:2012-06-01 00:00:00
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doi:10.1097/ADM.0000000000000065
更新日期:2014-11-01 00:00:00
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doi:10.1097/ADM.0000000000000599
更新日期:2020-07-01 00:00:00
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更新日期:2007-03-01 00:00:00
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doi:10.1097/ADM.0b013e3181db69ef
更新日期:2011-03-01 00:00:00
abstract::: COVID-19 pandemic has resulted in devastating mortality and morbidity consisting of socioeconomic and health effects that have included respiratory/pulmonary, cardiovascular, mental health and neurological consequences such as anxiety, depression, and substance use. Extensive efforts are underway to develop preventi...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000771
更新日期:2020-12-14 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:2016-11-01 00:00:00
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更新日期:2013-07-01 00:00:00
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journal_title:Journal of addiction medicine
pub_type: 杂志文章,评审
doi:10.1097/ADM.0b013e3182312863
更新日期:2012-03-01 00:00:00
abstract::Buprenorphine/naloxone maintenance therapy is often prescribed in primary care to treat opioid dependence. Previous reports have described concomitant abuse of opioids and clonidine. In this case, a primary care patient on buprenorphine/naloxone maintenance therapy demonstrating altered mental status, hallucinations, ...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000081
更新日期:2014-11-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-09-01 00:00:00
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更新日期:2008-01-01 00:00:00
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journal_title:Journal of addiction medicine
pub_type: 杂志文章
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更新日期:2019-01-01 00:00:00
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更新日期:2014-05-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Buprenorphine/naloxone has been shown to be an effective treatment of opioid use disorder. According to the Canadian National clinical practice guideline on the management of opioid use disorders, given the superior safety profile of buprenorphine/naloxone and its potential for flexible take-home dosing in c...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
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更新日期:2020-12-01 00:00:00