Abstract:
OBJECTIVE:The aim of the study is to determine length of stay and length of treatment in infants with neonatal abstinence syndrome (NAS) in the neonatal intensive care unit (NICU) compared to those in the pediatric floor. METHODS:Retrospective cohort of infants ≥34 weeks gestation admitted with diagnosis of NAS at a single regional perinatal referral center from July 2014 to October 2015. A standardized NAS protocol for both the NICU and pediatric floor, which included guidelines for the initiation of oral morphine, escalation, and weaning, was followed. Initial location of treatment, NICU or pediatric floor, was determined by physiological stability following birth. Statistical analysis included 1-way analysis of variance and chi-square. Multivariable analysis was performed using generalized linear models to account for confounding. RESULTS:The study included 235 infants, 80 (34%) were cared for in the NICU. Infants in the NICU had a longer length of stay (27.1 ± 19.1 vs 14.2 ± 10.2 days, P < 0.01), and length of pharmacological treatment (18.0 ± 19.9 vs 9.0 ± 10.2 days, P < 0.01) compared to those on the pediatric floor, respectively. Forty-seven infants were transferred from the NICU to the pediatric floor for the remainder of their hospital stay with a mean time on the pediatric floor of 17.4 ± 14.5 days. After controlling for confounding, admission to the NICU was associated with an increased length of treatment of 12.6 days (95% confidence interval 8.3-16.8) and length of stay of 12.3 days (95% confidence interval 7.9-16.6). CONCLUSIONS:In our population, admission to the pediatric floor compared to the NICU was associated with a shorter length of stay, and a shorter length of pharmacological treatment. Our data suggest that caring for infants with NAS outside of the NICU setting has the potential to improve short-term outcomes and reduce associated costs.
journal_name
J Addict Medjournal_title
Journal of addiction medicineauthors
Lembeck AL,Tuttle D,Locke R,Lawler L,Jimenez P,Mackley A,Paul DAdoi
10.1097/ADM.0000000000000455subject
Has Abstractpub_date
2019-01-01 00:00:00pages
75-78issue
1eissn
1932-0620issn
1935-3227journal_volume
13pub_type
杂志文章abstract:BACKGROUND:Buprenorphine/naloxone has been shown to be an effective treatment of opioid use disorder. According to the Canadian National clinical practice guideline on the management of opioid use disorders, given the superior safety profile of buprenorphine/naloxone and its potential for flexible take-home dosing in c...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000675
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVES:: Opioid detoxification with subsequent naltrexone is found to be an effective method as the first step in an abstinence-oriented approach. The aim of this study is to investigate the predictive value of variables for abstinence in opioid-dependent patients. METHODS:: Opioid-dependent patients were followed...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0b013e31818a6596
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVES:Cocaine is a known risk factor for several vascular ischemic events. The underlying mechanisms leading to the complications are not fully understood, although thrombus formation and accelerated atherosclerosis are prominent findings. Evidence of endothelial dysfunction (ED), a key phenomenon in the pathogene...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000109
更新日期:2015-03-01 00:00:00
abstract::The purpose of this study was to examine the correlates of recreational gambling in lower-income compared with middle/higher-income groups. We examined, by logistic regression, a nationally representative U.S. adult sample (n = 2417) from the 1998 Gambling Impact and Behavior Study (GIBS) to investigate the influence ...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0b013e318125088f
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVES:Screening, Brief Intervention, and Referral to Treatment (SBIRT) has demonstrated efficacy for addressing unhealthy alcohol use in primary care, yet recent research indicates weaker efficacy for drug use as well as very limited success in referral to specialty care for patients with substance use disorder (S...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000663
更新日期:2020-12-01 00:00:00
abstract::: Buprenorphine induction can be challenging for patients with chronic pain or patients who are unable to cease opioids for sufficient time to prevent precipitated opioid withdrawal. In the outpatient setting, low-dose buprenorphine induction strategies have been described to avoid these barriers; however, these strat...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000745
更新日期:2020-09-21 00:00:00
abstract::This clinical case presentation and discussion illustrates a culturally adapted alcohol and drug use intervention using the Screening, Brief Intervention, and Referral to Treatment (SBIRT) approach, incorporating motivational interviewing skills. This case conference serves to complement the accompanying review articl...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000149
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVES:Investigate patterns of methamphetamine use over time, specifically factors associated with remission from dependent and harmful patterns of use; and examine drug treatment and health/support service utilization pathways among people who use methamphetamine. METHODS:People who regularly use methamphetamine ...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000469
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVES:Individuals with substance use disorders (SUDs) have unique reproductive health needs. The aim of this study was to evaluate these needs and assess the acceptability of family planning service delivery of SUD treatment clients. METHODS:Reproductive health needs of drug treatment clients were assessed using ...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000175
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Screening for prenatal drug use is recommended. The NIDA-modified Alcohol, Smoking, and Substance Involvement Screening Test (NM-ASSIST) is a screener for drug use that has not yet been validated with pregnant women. This study aims to assess the substance-specific diagnostic validity of the NM-ASSIST (not i...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000614
更新日期:2020-09-01 00:00:00
abstract::Previous studies have demonstrated that cocaine use alters availability of brain dopamine D2 receptors (D2R) and transporters (DAT). The present study examined the effects of low doses of cocaine on this neuroadaptation. Using positron emission tomography (PET), D2R and DAT availability in the caudate nucleus (Cd), pu...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0b013e318045c038
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to evaluate retrospectively the prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection, epidemiological parameters, and the clinical data from the antiviral treatment of hepatitis C in a large cohort of intravenous drug users (IDUs) followed-up from 1994 until 2...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0b013e318279756f
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:The effects of cannabis on clinical outcomes of treatment services for other drug use disorders remains unclear. The primary aim of the current study was to investigate the effects of recent cannabis consumption on the severity of cocaine withdrawal and depressive symptoms during a 3-week inpatient treatment...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000599
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVES:Drop In Centers (DICs) are organizations in which health and social services are delivered to drug users on the basis of harm-reduction strategies. The aim of this epidemiological study was to estimate the prevalence of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infection at these centers...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000112
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVES:: This study characterizes patterns and correlates of prescription drug nonmedical (PDNM) use and prescription drug problem (PDP) use among U.S. adolescents. METHODS:: Using the 2003 National Survey on Drug Use and Health (NSDUH), we estimated annual prevalence of PDNM and PDP use. We stratified prevalence ...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0b013e31815b5590
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:The characteristics of patients with co-occurring chronic pain and prescription opioid abuse have not been well described, and even less is known about differences between men and women in this population. OBJECTIVES:This study evaluated sex differences in the demographic, diagnostic, and behavioral attribu...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000086
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Substance use disorders during pregnancy are a concern both to the public and medical community, because the negative consequences can be detrimental to both mother and the fetus. The accurate identification of prenatal drug exposure is necessary to determine appropriate medical and psychosocial intervention...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000521
更新日期:2019-11-01 00:00:00
abstract::Fetal alcohol spectrum disorders (FASDs) are conditions caused by prenatal alcohol exposure in amounts sufficient to cause permanent deficits in brain functioning. Extent of damage largely depends on timing, dose, frequency, and pattern of exposure. Timing is especially important because prenatal alcohol exposure duri...
journal_title:Journal of addiction medicine
pub_type: 杂志文章,评审
doi:10.1097/ADM.0b013e31828b47a8
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:Prescription Drug Monitoring Programs (PDMPs) are intended to help reduce prescription drug misuse and opioid overdose, yet little is known about the longitudinal patterns of opioid prescribing that may be associated with mortality. This study investigated longitudinal opioid prescribing patterns among patien...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000458
更新日期:2019-01-01 00:00:00
abstract::Benzodiazepines are a controversial treatment for anxiety in patients with substance use disorders. Concerns include risk of addiction, overdose, and diversion. But benzodiazepines are among the most effective and well-tolerated treatments for anxiety, and are safe for the majority of patients who take them. Though no...
journal_title:Journal of addiction medicine
pub_type: 社论
doi:10.1097/ADM.0000000000000292
更新日期:2017-03-01 00:00:00
abstract:OBJECTIVES:To measure the rates and predictors of clinician recommendation for follow-up after a positive screen for unhealthy drug use, in a context of mandatory routine screening. To measure response to clinician recommendations and identification of new drug use diagnoses. METHODS:Data are from a Veterans Health Ad...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000567
更新日期:2020-05-01 00:00:00
abstract::Although buprenorphine is approved for use in the outpatient treatment of opioid addiction in 2 tablet formulations, a monoproduct containing buprenorphine only (Subutex) and a buprenorphine/naloxone combination product (Suboxone), much of the clinical data that support the approval by the U.S. Food and Drug Administr...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0b013e31806dcc3e
更新日期:2007-06-01 00:00:00
abstract::: COVID-19 pandemic has resulted in devastating mortality and morbidity consisting of socioeconomic and health effects that have included respiratory/pulmonary, cardiovascular, mental health and neurological consequences such as anxiety, depression, and substance use. Extensive efforts are underway to develop preventi...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000771
更新日期:2020-12-14 00:00:00
abstract:OBJECTIVES:Women with opioid use disorder (OUD) in the USA are at risk for poor reproductive and sexual health (RSH) outcomes. The qualitative research presented here is part of a larger mixed methods study. The qualitative component used an implementation science framework to investigate provider and staff perspective...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000657
更新日期:2020-09-01 00:00:00
abstract::Opioid dependent pregnant and post-partum women and their infants are a complex and vulnerable population requiring individualized, comprehensive and multidisciplinary treatment. Though methadone maintenance in the setting of comprehensive service provision during pregnancy significantly improves pregnancy outcomes fo...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0b013e31817e6105
更新日期:2008-09-01 00:00:00
abstract::The Centers for Disease Control have recently described opioid use and resultant deaths as an epidemic. At this point in time, treating this disease well with medication requires skill and time that are not generally available to primary care doctors in most practice models. Suboptimal treatment has likely contributed...
journal_title:Journal of addiction medicine
pub_type: 杂志文章,实务指引
doi:10.1097/ADM.0000000000000166
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVES:Provision of smoking-cessation treatment is limited in office-based buprenorphine maintenance treatment (BMT) settings. This study describes smoking and smoking-cessation behaviors among patients receiving office-based BMT. METHODS:Cross-sectional study of patients receiving office-based BMT at a community ...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000356
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:Medications for opioid use disorder (MOUD) and alcohol use disorder (MAUD) are effective and under-prescribed. Hospital-based addiction consult services can engage out-of-treatment adults in addictions care. Understanding which patients are most likely to initiate MOUD and MAUD can inform interventions and d...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000611
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVES:Although the relation between impulsivity and smoking is well-documented, one model of impulsivity that has received little attention in the addiction literature separates impulsivity into 2 dimensions: functional impulsivity (tendency to make quick effective decisions) and dysfunctional impulsivity (tendenc...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0b013e31825e2a67
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVES:Cannabis is the most commonly used illicit drug; a substantial minority of users develop dependence. The current lack of pharmacological treatments for cannabis dependence warrants the use of novel approaches and further investigation of promising pharmacotherapy. In this case series, we assessed the use of ...
journal_title:Journal of addiction medicine
pub_type: 临床试验,杂志文章
doi:10.1097/ADM.0000000000000229
更新日期:2016-07-01 00:00:00