Abstract:
:Fetal alcohol spectrum disorders (FASDs) are conditions caused by prenatal alcohol exposure in amounts sufficient to cause permanent deficits in brain functioning. Extent of damage largely depends on timing, dose, frequency, and pattern of exposure. Timing is especially important because prenatal alcohol exposure during critical periods of gestation can affect brain development in ways that produce varying patterns of neurocognitive deficits and associated adaptive impairments. This article describes some of the more serious neurophysiological and neuropsychological sequelae of prenatal alcohol exposure that contribute to increased risk for substance abuse problems among people with an FASD. We discuss the unique interface between pharmacological treatment and FASD, noting that failure to consider the possibility of FASD in treatment planning may result in treatment failure and/or relapse. Finally, we present a clinical case example and recommend service accommodations to address some of the impairments in FASD that limit substance abuse treatment success.
journal_name
J Addict Medjournal_title
Journal of addiction medicineauthors
Grant TM,Brown NN,Dubovsky D,Sparrow J,Ries Rdoi
10.1097/ADM.0b013e31828b47a8subject
Has Abstractpub_date
2013-03-01 00:00:00pages
87-95issue
2eissn
1932-0620issn
1935-3227pii
01271255-201303000-00001journal_volume
7pub_type
杂志文章,评审abstract:OBJECTIVES:The aim of this study was to evaluate retrospectively the prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection, epidemiological parameters, and the clinical data from the antiviral treatment of hepatitis C in a large cohort of intravenous drug users (IDUs) followed-up from 1994 until 2...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0b013e318279756f
更新日期:2013-01-01 00:00:00
abstract::: With the growing public interest in the potential therapeutic benefits of cannabis and cannabinoids in the treatment of opioid use disorder (OUD), some states have now either added or proposed to add OUD as an indication for their state's medical marijuana program. However, these initiatives are based on weak eviden...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000711
更新日期:2020-09-08 00:00:00
abstract:OBJECTIVE:To determine whether the methadone maintenance treatment (MMT) affects sleep. METHODS:We prospectively followed up the sleep pattern of 23 opiate addicts when admitted to MMT and after 6 and 12 months of treatment. Pittsburgh Sleep Quality Index, pain self-report questionnaires, urine for drug abuse, and one...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0b013e3181e8b6c4
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVES:The present study aims to describe a 3-day induction protocol for injectable hydromorphone (HDM) and diacetylmorphine (DAM) used in 3 Canadian studies and examine rates of opioid-related overdose and somnolence during this induction phase. METHODS:The induction protocol and associated data on opioid-related...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000505
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVES:Drop In Centers (DICs) are organizations in which health and social services are delivered to drug users on the basis of harm-reduction strategies. The aim of this epidemiological study was to estimate the prevalence of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infection at these centers...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000112
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVE:Patients with substance use disorders (SUDs) prescribed long-term opioid therapy (LtOT) are at risk for overdose and mortality. Prior research has shown that receipt of LtOT in accordance with clinical practice guidelines has the potential to mitigate these outcomes. Our objective was to determine whether the...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000255
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Does performing pre-employment hair drug testing subsequently affect the prevalence of positive random and postaccident urine drug tests? METHODS:This cross-sectional study was designed to evaluate the prevalence of positive postaccident and random workplace urine drug tests for companies that perform pre-e...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000384
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:Individuals with psychiatric disease, substance abuse, and/or housing instability have a high prevalence of chronic hepatitis C virus (HCV) infection. However, such individuals are often excluded from treatment for HCV infection because of a perceived inability to adhere to the rigorous medication regimen re...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0b013e31829b1a6c
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVES:Screening, Brief Intervention, and Referral to Treatment (SBIRT) has demonstrated efficacy for addressing unhealthy alcohol use in primary care, yet recent research indicates weaker efficacy for drug use as well as very limited success in referral to specialty care for patients with substance use disorder (S...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000663
更新日期:2020-12-01 00:00:00
abstract::This case study of the development and implementation of an opioid overdose prevention program is based on an actual clinic's experience, but information about the clinic, including details of implementation and outcome measures, has been changed. Four experts reflect on the medical, administrative, peer-support, comm...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000032
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVES:To describe the reproductive health needs of women who inject drugs (WWID) and are participants in a syringe exchange program (SEP) in Hawaii. Our secondary objective was to develop and pilot services in response to those needs. METHODS:We conducted a reproductive health needs-assessment of women participat...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000508
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Buprenorphine/naloxone has been shown to be an effective treatment of opioid use disorder. According to the Canadian National clinical practice guideline on the management of opioid use disorders, given the superior safety profile of buprenorphine/naloxone and its potential for flexible take-home dosing in c...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000675
更新日期:2020-12-01 00:00:00
abstract::Four young ketamine abusers with lower urinary tract symptoms presented to regional hospitals in Shenzhen, China. Investigations demonstrated contracted bladders and other urinary tract abnormalities. There have been few reports of similar findings in ketamine abusers in the Chinese mainland. We followed up each patie...
journal_title:Journal of addiction medicine
pub_type: 杂志文章,评审
doi:10.1097/ADM.0b013e3182312863
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVES:Although smoking is a major health issue among depressed psychiatric inpatients and interest in quitting is high, successful quit rates remain low among this population. We sought to understand preferences that depressed inpatient smokers may have for cessation treatments. METHODS:Eighty smokers (60% women,...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000027
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Substance use disorders during pregnancy are a concern both to the public and medical community, because the negative consequences can be detrimental to both mother and the fetus. The accurate identification of prenatal drug exposure is necessary to determine appropriate medical and psychosocial intervention...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000521
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVES:Cocaine abuse is widespread in Europe, and Ireland ranks among the leading countries for prevalence of cocaine use among adolescents. This study aimed to examine demographic and substance use correlates of lifetime cocaine use among adolescents with substance use disorder, and to explore the relationship bet...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0b013e318288daa2
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVES:To assess methadone maintenance treatment (MMT) patients' willingness to use, and perceived efficacy of, conventional and unconventional group stress reduction treatments. METHODS:A survey, developed by the authors, was administered to 150 MMT patients. RESULTS:Levels of treatment willingness and perceived...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0b013e3181ee77cl
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVES:Women with opioid use disorder (OUD) in the USA are at risk for poor reproductive and sexual health (RSH) outcomes. The qualitative research presented here is part of a larger mixed methods study. The qualitative component used an implementation science framework to investigate provider and staff perspective...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000657
更新日期:2020-09-01 00:00:00
abstract::: The Grayken Center for Addiction at Boston Medical Center includes programs across the care continuum for people with substance use disorders (SUDs), serving both inpatients and outpatients. These programs had to innovate quickly during the COVID-19 outbreak to maintain access to care. Federal and state regulatory f...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000791
更新日期:2020-12-08 00:00:00
abstract:INTRODUCTION:There are several brief screening tools for gambling that possess promising psychometric properties, but have uncertain utility in generalist healthcare environments which prioritize prevention and brief interventions. This study describes an examination of the National Opinion Research Centre Diagnostic a...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000429
更新日期:2018-11-01 00:00:00
abstract:OBJECTIVES:To prospectively evaluate QTc changes among methadone maintenance treatment (MMT) patients. METHODS:All 512 opiate addicts newly admitted to 2 MMT clinics had been prospectively studied for 4.5 years. Ninety-one patients were excluded because they were admitted from other MMTs, and 26 were excluded because ...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0b013e3182a8a4f2
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND AND AIMS:Medication-overuse headache (MOH) is a common chronic headache caused by overuse of headache analgesics. It has similarities with substance dependence disorders. The treatment of choice for MOH is withdrawal of the offending analgesics. Behavioral brief intervention treatment using methods adapted f...
journal_title:Journal of addiction medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/ADM.0000000000000504
更新日期:2019-09-01 00:00:00
abstract::Previous studies have demonstrated that cocaine use alters availability of brain dopamine D2 receptors (D2R) and transporters (DAT). The present study examined the effects of low doses of cocaine on this neuroadaptation. Using positron emission tomography (PET), D2R and DAT availability in the caudate nucleus (Cd), pu...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0b013e318045c038
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND:Medications for opioid use disorder (MOUD) and alcohol use disorder (MAUD) are effective and under-prescribed. Hospital-based addiction consult services can engage out-of-treatment adults in addictions care. Understanding which patients are most likely to initiate MOUD and MAUD can inform interventions and d...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000611
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVES:The present research explored the effect of reward sensitivity bias and metacognitive deficits on substance use disorder (SUD) in the decision-making process. METHODS:The behavioral activation system (BAS) was used as a predictive marker of dysfunctional behavior during the Iowa gambling task (IGT). We also...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000065
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVES:Individuals with substance use disorders (SUDs) have unique reproductive health needs. The aim of this study was to evaluate these needs and assess the acceptability of family planning service delivery of SUD treatment clients. METHODS:Reproductive health needs of drug treatment clients were assessed using ...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000175
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVES:: This study characterizes patterns and correlates of prescription drug nonmedical (PDNM) use and prescription drug problem (PDP) use among U.S. adolescents. METHODS:: Using the 2003 National Survey on Drug Use and Health (NSDUH), we estimated annual prevalence of PDNM and PDP use. We stratified prevalence ...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0b013e31815b5590
更新日期:2008-03-01 00:00:00
abstract:OBJECTIVES:Efforts to improve buprenorphine access for opioid use disorder have focused on increasing the number of waivered providers. However, it is unknown how efforts to increase initial prescribing result in a sustained pool of prescribers. We examine the prevalence of year-to-year provider-level buprenorphine pre...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000765
更新日期:2020-11-03 00:00:00
abstract:OBJECTIVES:: To describe trends in court-mandated treatment in pregnancy. In particular, to determine whether pregnant women who enter treatment via the criminal justice system differ from women who enter voluntarily. METHODS:: Data were obtained from the Treatment Episode Data Set, an administrative data set that cap...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0b013e3181b562dc
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVES:We assessed sex differences in a sample of first-admission psychiatric inpatients with and without comorbid substance use disorder (SUD) to identify possible risk factors and targets for sex-tailored treatment interventions. METHODS:A retrospective study of first admissions to the University Psychiatry Ward...
journal_title:Journal of addiction medicine
pub_type: 杂志文章
doi:10.1097/ADM.0000000000000062
更新日期:2014-09-01 00:00:00