Abstract:
:This special issue addresses the heritability and molecular genetic basis of 17 putative endophenotypes involving resting EEG power, P300 event-related potential amplitude, electrodermal orienting and habituation, antisaccade eye tracking, and affective modulation of the startle eye blink. These measures were collected from approximately 4,900 twins and parents who provided DNA samples through their participation in the Minnesota Twin Family Study. Included are papers that detail the methodology followed, genome-wide association analyses of single nucleotide polymorphisms and genes, analysis of rare variants in the human exome, and a whole genome sequencing study. Also included are 11 articles by leading experts in psychophysiology and genetics that provide perspective and commentary. A final integrative report summarizes findings and addresses issues raised. This introduction provides an overview of the aims and rationale behind these studies.
journal_name
Psychophysiologyjournal_title
Psychophysiologyauthors
Iacono WGdoi
10.1111/psyp.12340subject
Has Abstractpub_date
2014-12-01 00:00:00pages
1201-2issue
12eissn
0048-5772issn
1540-5958journal_volume
51pub_type
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