Abstract：
:Mature and healthy male lesser bandicoot rats, Bandicota bengalensis (n = 40) were fed on bait (mixture of cracked wheat and powdered sugar in 98:2) containing different concentrations of triptolide (0, 0.15, 0.20 and 0.25% w/w) for 15 days in two-choice trials. Results revealed no significant effect of triptolide treatment on weights of vital organs after 30 and 60 days of treatment withdrawal. A significant (P ≤ 0.05) increase in plasma levels of TP, ALP, ACP, ALT and AST in response to stress induced in groups of rats treated with 0.20 and 0.25% triptolide was observed after 30 days of treatment withdrawal. No significant effect of treatment was observed on histomorphology of liver. A significant (P ≤ 0.05) effect of triptolide treatment was, however, observed on testicular function in the form of reduced diameter of seminiferous tubules and number of various spermatogenic cells indicating effect on spermatogenesis and spermiogenesis. The cell stages affected did not recover fully within 60 days period following treatment withdrawal. The present study suggests the potential of triptolide in the reproductive management of B. bengalensis by way of affecting testicular function.
journal_name
Pestic Biochem Physioljournal_title
Pesticide biochemistry and physiologyauthors
Dhar P,Singla Ndoi
10.1016/j.pestbp.2014.09.012subject
Has Abstractpub_date
2014-11-01 00:00:00pages
49-55eissn
0048-3575issn
1095-9939pii
S0048-3575(14)00165-5journal_volume
116pub_type
杂志文章abstract：:The two-spotted spider mite Tetranychus urticae is a serious pest of many agricultural crops and ornamental plants. The sublethal effects of a new chemical, spinetoram, on T. urticae were investigated by treating adult females and eggs with LC10 and LC20 in the laboratory. The data were assessed based on age-stage, tw...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2016.02.002
更新日期：2016-09-01 00:00:00
abstract：:The aim of this study was to assess the effects and reversibility of the synthetic estrogen compound, quinestrol, on the reproductive organs, steroid hormones, and drug-metabolizing enzymes CYP3A4 and CYP1A2 in liver and kidney over time after two quinestrol treatments in female Mongolian gerbils (Meriones unguiculatu...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2017.08.008
更新日期：2017-11-01 00:00:00
abstract：:The tomato leafminer, Tuta absoluta, now a major pest of tomato crops worldwide, is primarily controlled using chemical insecticides. Recently, high levels of resistance to the insecticide spinosad have been described in T. absoluta populations in Brazil. Selection of a resistant field-collected strain led to very hig...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2016.02.006
更新日期：2016-07-01 00:00:00
abstract：:Combined application of plant essential oils (EOs) with known antimicrobial effects and silica nanocapsules with high loading capacity and protection capability of the EOs make them proper candidates for creating environmentally friendly fungicides. In this study, EOs of the Lemongrass (LGO) and Clove (CO) were used a...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2020.104696
更新日期：2020-11-01 00:00:00
abstract：:The acute toxicity of fipronil and its sublethal effects on detoxification enzymes (carboxylesterases (CarEs), glutathione S-transferases (GSTs), and 7-ethoxycoumarin O-deethylase (ECOD)) in zebrafish (Danio rerio) were investigated. The results indicated that the 24-h LC50 of fipronil for zebrafish was 220.4 μg/L (95...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2014.07.010
更新日期：2014-10-01 00:00:00
abstract：:1-Deoxynojirimycin (DNJ) is a natural d-glucose analogue from mulberry with promising physiological activity in vivo. Up to the present, the antidiabetic effects of DNJ on lowering blood sugar and accelerating lipid metabolism in mammals were broadly reported, but the specific character of DNJ against insects was vast...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2018.08.009
更新日期：2018-11-01 00:00:00
abstract：:Aedes aegypti mosquitoes are responsible for dengue, chikungunya, and Zika virus transmission in tropical and subtropical areas around the world. Due to the absence of vaccines or antiviral drugs for human treatment, the majority of control strategies are targeted at Ae. aegypti elimination. Our research on mosquito c...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2017.11.006
更新日期：2018-01-01 00:00:00
abstract：:Deltamethrin belongs to the class of synthetic pyrethroids, which are being widely used as insecticides in agricultural practices. Voltage-gated sodium channels (VGSCs) are the primary targets of these chemicals for toxicity to insects. Caenorhabditis elegans (C. elegans) does not have VGSCs but is susceptible to delt...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2017.03.005
更新日期：2017-05-01 00:00:00
abstract：:There has been a considerable growth in interest to use RNA interference (RNAi) as a novel insect pest management strategy in the past 10 years. However, there has been virtually no information on insect population variations in response to double-stranded RNA (dsRNA) molecules. The objective of this study was to gene...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2018.06.005
更新日期：2018-07-01 00:00:00
abstract：:The purpose of this research was to explore the effect of phenazine-1-carboxamide (PCN) on Rhizoctonia solani and to elucidate its mechanisms of action. The toxicity of PCN to R. solani was measured using a growth rate method. The results indicated that PCN inhibited R. solani with a 50% effective concentration (EC50)...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2017.10.006
更新日期：2018-05-01 00:00:00
abstract：:Pyrethrum extract (PY) is a natural insecticide that is extensively used across the world, and its insecticidal activity is attributed to the presence of six active esters known as pyrethrins. PY targets the nervous systems of insects by delaying the closure of voltage-gated sodium ion channels in the nerve cells. How...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2016.09.003
更新日期：2017-04-01 00:00:00
abstract：:2-Allylphenol (2-AP) is an effective fungicide against a number of plant pathogens, which can be metabolized and bio-transformed to four chemical compounds by Rhizoctonia cerealis. To determine if its degradation affects antifungal activity, two major metabolites derived from 2-AP including 2-(2-hydroxypropyl) phenol ...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2016.06.006
更新日期：2017-01-01 00:00:00
abstract：:Synergism and metabolic studies were conducted to identify the resistance mechanism against indoxacarb in two Choristoneura rosaceana (Harris) field populations compared to a susceptible population. The synergism study was carried out using diet incorporation bioassay for indoxacarb and the three synergists PBO, DEM, ...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2020.104636
更新日期：2020-09-01 00:00:00
abstract：:Sodium channel blocker insecticides (SCBIs) are a relatively new class of insecticides, with a mechanism of action different from those of other classes of insecticides that target voltage-gated sodium channels. These compounds have no effect at hyperpolarized membrane potentials, but cause a voltage-dependent, nearly...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2009.09.001
更新日期：2010-06-01 00:00:00
abstract：:Antidesmone, isolated from Waltheria brachypetala Turcz., owns special structural features as two α,β-unsaturated carbonyl groups and a side alkyl chain that can compete with the quinones involved in the pool of plastoquinones at photosystem II (PSII). In this work, we showed that the alkaloid is an inhibitor of Hill ...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2016.04.006
更新日期：2016-11-01 00:00:00
abstract：:Honeybees ensure a key ecosystemic service by pollinating many agricultural crops and wild plants. However, since few decades, managed bee colonies have declined worldwide. This phenomenon is considered to be multifactorial, with a strong emphasis on both parasites and pesticides. Infection by the parasite Nosema cera...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2019.11.006
更新日期：2020-02-01 00:00:00
abstract：:Human population bears the brunt of deadly hepatotoxic, neurodegenerative, behavioural and various other developmental disorders due to pesticide toxicity through environmental or occupational exposures. The application of pesticides to control pests in land and water has posed potential health hazards to live stock a...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章,评审
doi：10.1016/j.pestbp.2014.04.007
更新日期：2014-06-01 00:00:00
abstract：:Neurophysiological recordings were employed to quantify neuronal sensitivity to neurotoxic insecticides and assessed toxicity across field and laboratory fall armyworm (FAW) populations. Topical toxicity resistance ratios (RR) in field-collected FAW was 767-fold compared to laboratory strains and, importantly, a 1750-...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2020.104652
更新日期：2020-10-01 00:00:00
abstract：:Although it is well known that Bacillus thuringiensis Cry toxins kill insect pest by disrupting midgut cells of susceptible larvae through their pore formation activity, it is not clear what intracellular events are triggered after pore formation on the cell membrane of the target cells. Here we analyzed the role of C...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2020.104728
更新日期：2021-01-01 00:00:00
abstract：:Carboxylesterases (CarEs) play important roles in metabolism and detoxification of dietary and environmental xenobiotics in insects and mites. On the basis of the Tetranychuscinnabarinus transcriptome dataset, 23 CarE genes (6 genes are full sequence and 17 genes are partial sequence) were identified. Synergist bioass...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2015.12.007
更新日期：2016-07-01 00:00:00
abstract：:The brown planthopper, Nilaparvata lugens (Stål) (Hemiptera: Delphacidae), is a typical pest in which population resurgence can be induced by insecticides. Warmer global temperatures, associated with anthropogenic climate change, are likely to have marked ecological effects on terrestrial ecosystems. However, the effe...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2014.11.010
更新日期：2015-02-01 00:00:00
abstract：:Galectins are a family of β-galactoside binding proteins, and insect galectins play a role in immune responses and may also affect Cry toxin activity. In this study, we aimed to further understand the function and molecular mechanism of Aedes aegypti galectin-6 in modulation of Cry11Aa toxicity. A. aegypti galectin-6 ...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2019.09.010
更新日期：2020-01-01 00:00:00
abstract：:Imazethapyr (IMZT) is a typical chiral pesticide with two enantiomers with the R-IMZT having the main herbicidal activity. However, the enantioselectivity of the effects of IMZT enantiomers on human and animals is still unclear. In this study, a nuclear magnetic resonance (NMR)-based metabolomics method and determinat...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2020.104619
更新日期：2020-09-01 00:00:00
abstract：:The beet armyworm, Spodoptera exigua (Hübner) (Lepidoptera: Noctuidae) is a highly polyphagous pest which causes considerable economic losses to cotton and many vegetable crops. Tannins are among the most important secondary metabolites in cotton plants. We show that tannic acid enhances the toxic effect of chlorantra...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2019.01.012
更新日期：2019-03-01 00:00:00
abstract：:Selectivity to insects over mammals is one of the important characteristics for a chemical to become a useful insecticide. Fipronil was found to block cockroach GABA receptors more potently than rat GABA(A) receptors. Furthermore, glutamate-activated chloride channels (GluCls), which are present in cockroaches but not...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2009.07.008
更新日期：2010-06-01 00:00:00
abstract：:Although phosphite (Phi)-based fertilizers are used in large quantities in agriculture, the use of Phi-based fungicides against soybean root rot caused by Phytophthora sojae are limited. While, their low toxicity are of high ecological and economic focus. Limited attention has been paid to Phi translocation efficiency...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2020.104757
更新日期：2021-02-01 00:00:00
abstract：:Malathion is one of the most commonly used organophosphorus (OP) pesticides. It is important to regard that exposure to OP poisoning may cause anxiety and depression. Malathion toxicity induces cholinergic symptoms. Brain-derived neurotrophic factor (BDNF) is the most profusely expressed neurotrophin in the central ne...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2019.01.014
更新日期：2019-06-01 00:00:00
abstract：:A series of novel aryloxyphenoxypropionate (APP) herbicides containing benzofuran moiety were designed, synthesized and tested for herbicidal activity. The bioassay results indicated that most of target compounds possessed moderate to good herbicidal activity against monocotyledonous weeds. Compounds 5a-5d and 6a-6d s...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2018.12.011
更新日期：2019-02-01 00:00:00
abstract：:Although there have been many reports on the synergistic interactions among the major constituents of plant essential oils regarding insecticidal activity, their underlying mechanism of synergy is poorly understood. In our previous studies, we found each of the two most abundant constituents of rosemary (Rosmarinus of...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2017.01.012
更新日期：2017-08-01 00:00:00
abstract：:Polyunsaturated fatty acids usually undergo lipid peroxidation induced by reactive oxygen species (ROS). Calcium-independent cellular phospholipase A2 (iPLA2) can maintain fatty acid compositions in phospholipids depending on physiological conditions. An insect iPLA2 (Pi-iPLA2) was predicted from the transciptome of t...
journal_title：Pesticide biochemistry and physiology
pub_type： 杂志文章
doi：10.1016/j.pestbp.2017.09.010
更新日期：2017-11-01 00:00:00
