Abstract:
BACKGROUND:Surgical resection of pulmonary aspergilloma is associated with symptoms control, complications prevention, and improved survival, given that the disease is localized and the patient fit enough to undergo surgery. In these operable forms, the impact of perioperative antifungal therapy remains controversial. The purpose of this study was to analyze the impact of antifungal therapy on postoperative morbidity and overall survival in patients with operable pulmonary aspergilloma. METHODS:The clinical records of 113 patients who underwent thoracic surgery for aspergilloma in our institution from January 1989 to December 2010 were retrospectively reviewed. Of these, 64 patients received antifungal therapy in the perioperative period and were included in group 1, and 49 patients did not receive antifungal therapy and were included in group 2. RESULTS:Postoperative complication rates were 31.2% in group 1 and 20.4% in group 2 (P = 0.30). Univariable analysis showed that immunocompromised status (P < 0.001), past history of cancer (P = 0.50), preoperative purulent sputum (P = 0.024), and pneumonectomy (P < 0.001) were significantly associated with postoperative complications, but that antifungal therapy was not. Five- and 10-year overall survival rates were respectively 78.3% and 57.8% in group 1 vs. 85.9% and 65.7% in group 2 (P = 0.23). Multivariate analysis revealed that age higher than 50, immunocompromised status and pneumonectomy were significantly associated with adverse long-term survival (χ(2) = 6.59, df = 5, P < 0.001), but that antifungal therapy was not. CONCLUSION:Antifungal therapy has no significant impact on postoperative morbidity or long-term survival following surgical resection of pulmonary aspergilloma. Such procedure is associated with acceptable postoperative morbidity and long-term survival.
journal_name
Rev Pneumol Clinjournal_title
Revue de pneumologie cliniqueauthors
Pagès PB,Grima R,Mordant P,Grand B,Badia A,Le Pimpec-Barthes F,Bernard A,Riquet Mdoi
10.1016/j.pneumo.2014.08.002subject
Has Abstractpub_date
2014-12-01 00:00:00pages
322-8issue
6eissn
0761-8417issn
1776-2561pii
S0761-8417(14)00121-7journal_volume
70pub_type
杂志文章abstract::Melioidosis is most frequently encountered in pulmonary localization. Melioidosis is an infectious disease caused by Burkholderia pseudomallei first described by Whitmore in 1912 in Burma. B. pseudomallei is a Gram negative rod belonging to the Pseudomonadaceae family. Soil and water are the natural reservoirs for the...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章,评审
doi:
更新日期:1998-12-01 00:00:00
abstract::The large majority of patients with acute respiratory failure present diffuse pulmonary opacities resulting from pulmonary embolism, intra-alveolar hemorrhage, or a classical cause of ARDS. In a small number of patients however, these opacities correspond to diffuse interstitial pneumonia. This should be suspected in ...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章,评审
doi:10.1016/s0761-8417(05)84792-3
更新日期:2005-04-01 00:00:00
abstract::Between 1990 and 1993 we observed 10 cases of spinal tuberculosis. Magnetic resonance imaging largely contributed to diagnosis and detection of early neurological complications. Medical treatment is essential and must be given for a sufficient duration. Indications for surgery are exceptional and are usually reserved ...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章,评审
doi:
更新日期:1996-01-01 00:00:00
abstract::Vitamin K antagonists are the mainstay for the treatment for venous thromboembolism. The optimum (VTE) course of oral anticoagulant therapy is determined according to the risk of recurrent VTE after stopping anticoagulant therapy and the risk of anticoagulant-related bleeding while on antivitamin K. The risk of recurr...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章,评审
doi:10.1016/j.pneumo.2008.09.007
更新日期:2008-12-01 00:00:00
abstract:UNLABELLED:Exacerbations of chronic obstructive pulmonary disease (COPD) have an inflammatory component in addition to the possible infectious component. The antiinflammatory properties of fenspiride (Pneumorel(R) 80 mg) should be evaluated in this frequent clinical situation. OBJECTIVES:Assess the supplementary thera...
journal_title:Revue de pneumologie clinique
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:2000-02-01 00:00:00
abstract::Forty-five bronchoalveolar lavages (BAL) were performed in Brazzaville in AIDS patients who did not expectorate acid- and alcohol-resistant bacilli (AARB). All patients presented with respiratory symptoms (cough, dyspnoea or chest pain), and all but 6 of them had abnormal radiography of the chest. Four cases of pneumo...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章,评审
doi:
更新日期:1991-01-01 00:00:00
abstract::Asthma is a very common disease and may be encountered in pregnant women. The physiological changes which accompany pregnancy, as well as the risks of drug teratogenicity and drug interactions make it necessary to take certain therapeutic precautions. Following a review of the specific respiratory physiological change...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::Gaucher's disease is a not exceptional lysosomial disease in Tunisia. Type 1 is by far the most common one. Pulmonary involvement is considered to be rare in type 1 Gaucher's disease. Pulmonary hypertension, infiltration of the lungs with Gaucher cells, and severe hypoxemia due to intrapulmonary arterial-venous shunts...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:10.1016/j.pneumo.2011.07.002
更新日期:2012-02-01 00:00:00
abstract:INTRODUCTION:Necrotizing fasciitis is a rapidly progressive and often fatal infection of the soft-tissue fascia deep to the skin but superficial to the muscles. We report a case of necrotizing fasciitis of the anterior chest wall complicating a percutaneous needle biopsy. CASE:A 49-year-old diabetic patient, presented...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:10.1016/s0761-8417(07)92652-8
更新日期:2007-09-01 00:00:00
abstract:INTRODUCTION:In spite of recommendations of the highest level of proof (rank A), the respiratory rehabilitation remains very widely sub-prescribed by general practitioners, who are nevertheless in the front line in the care and the follow-up of the patients affected by BPCO. MATERIAL AND METHODS:Semi-qualitative study...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:10.1016/j.pneumo.2017.03.002
更新日期:2017-06-01 00:00:00
abstract::The plathypnea orthodeoxia syndrome is a rare condition that is characterized by dyspnea and hypoxia that occurs in the upright position and improves with recumbency. The diagnostic is often made tardively and requires the combination of two components: a mechanical one (for example a patent foramen ovale) and a kinet...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:10.1016/j.pneumo.2016.12.007
更新日期:2017-04-01 00:00:00
abstract::Efficacy and tolerance of home non-invasive ventilation (NIV) must be assessed by using objective criteria (clinical evaluation, arterial blood gases, oxymetry, and research of side effects such as air leaks, skin problems, etc). In this article, we describe a procedure for long-term follow-up of home NIV. We also sug...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:10.1016/j.pneumo.2009.07.006
更新日期:2009-08-01 00:00:00
abstract::The prevalence of smoking in France remains very high compared to other developed Western countries. The management of smoking in smokers is often limited to nicotinic substitution, whether medicated or linked to the use of electronic cigarettes or varenicline and advices more or less reliable or helpful. This strateg...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章,评审
doi:10.1016/j.pneumo.2017.09.005
更新日期:2017-12-01 00:00:00
abstract::Since 1996, AIDS-related mortality has declined considerably with the introduction of tritherapy (HAART). This decline in mortality has been associated with an increase in the proportion of deaths caused by cancers unrelated to AIDS, particularly lung cancer. The risk of developing lung cancer is higher in the HIV-ser...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章,评审
doi:10.1016/s0761-8417(07)90121-2
更新日期:2007-06-01 00:00:00
abstract:INTRODUCTION:Intrapleural rupture of pulmonary hydatid cyst (PHC) is a rare but dangerous complication. The purpose of this study was to report the characteristics of this form of thoracic hydatidosis and analyze the favoring factors. MATERIALS AND METHODS:Between 1996 and 2011, 75 patients were operated in our depart...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:10.1016/j.pneumo.2013.12.006
更新日期:2014-08-01 00:00:00
abstract::Mucormycosis is a rare, devastating, opportunistic fungal infection, which occurs principally in some particular conditions, specially in non-controlled diabetic patients, notably during keratoacidosis. We report two cases in 62 and 72 year-old diabetic women. In both cases, histologic examination of endobronchial bio...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:10.1016/s0761-8417(06)75412-8
更新日期:2006-02-01 00:00:00
abstract::The Von Recklinghausen disease is a genetic hereditary neurofibromatosis. It causes neurofibroma, axillary and inguinal lentigines, and café-au-lait spots in the skin. It may affect the lung in 5 to 20% of cases, causing neurofibroma, infiltrative and cystic lesions, emphysematous or bubble injury leading to a chronic...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:10.1016/j.pneumo.2011.08.001
更新日期:2012-06-01 00:00:00
abstract::A study devised to evaluate the effects of chronic exposure to tobacco smoke on the health of a population of non-smokers was conducted in a prison. Fourteen volunteers among male, non-smoking prisoners in good health and without history of lung disease were put for thirty days in a cell that was already occupied by t...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
abstract::We report an atypical presentation of hemothorax. Tamponade and subacute dyspnea occurred secondary to a wound of the right atrium caused by a pacemaker electrode in 78-year-old woman on oral anticoagulants for complete arrhythmia due to atrial fibrillation. This case illustrate an unusual pathophysiological mechanism...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:10.1016/s0761-8417(05)84782-0
更新日期:2005-02-01 00:00:00
abstract::Lung diseases that occur in patients with drug-induced bone marrow aplasia are part of a wider group of lung diseases in immunocompromised patients. Their most common causes are infections due to Gram-negative bacilli, staphylococci or Aspergillus spp. and intra-alveolar haemorrhages. Their diagnostic approach is ofte...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章,评审
doi:
更新日期:1988-01-01 00:00:00
abstract::The impact of nosocomial tuberculosis remains poorly known. There is a real risk that is relatively higher when the probability of community acquisition declines. Diagnosis is difficult due to the natural history of tuberculosis infection so that most cases of nosocomial contamination result in infection without disea...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章,评审
doi:
更新日期:2001-04-01 00:00:00
abstract::The authors report a case of a large ganglioneurinoma located in the mediastinum. The clinical course of this rare benign neurogenic tumour of the posterior mediastinum includes a low risk of medullary compression. The treatment is surgical resection. ...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章,评审
doi:
更新日期:1994-01-01 00:00:00
abstract::Constrictive pericarditis was diagnosed in four patients who presented respiratory impairment and pleural effusion, associated with right ventricular failure in two. The cause was probable tuberculosis in two cases, post-irradiation lesions in one and unknown in one. The diagnosis was suspected due to the normal heart...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:
更新日期:1998-02-01 00:00:00
abstract::Few studies have described pulmonary non-infectious diseases (PNID) in patients with common variable immunodeficiency (CVID). Indeed the most frequent complications in these patients are infectious. The aim of our study is to analyze the characteristics of PNID in a retrospective study of patients with CVID of two pne...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:10.1016/j.pneumo.2011.06.005
更新日期:2011-09-01 00:00:00
abstract:INTRODUCTION:In some Tunisian cities, especially semi-urbanized, the exposure to the smoke produced during combustion of the biomass, main source of pollution of indoor air, remains prevalent among non-smoking women. AIM:To assess the relationship between exposure to biomass smoke and the presence of obstructive venti...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:10.1016/j.pneumo.2016.10.004
更新日期:2017-04-01 00:00:00
abstract::Complications observed after lung transplantation are well described for the different indications. Certain complications are specifically observed in patients with cystic fibrosis who have reached the stage of major respiratory failure. The most specific complications result from digestive tract manifestations of the...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章,评审
doi:
更新日期:2002-12-01 00:00:00
abstract:OBJECTIVE:To describe the clinical features of dry cough, its socio-professional consequences and impact on patients' quality of life. METHOD:Cross-sectional observational study conducted in daily practice of general practice. RESULTS:One thousand and six hundred and five patients aged 43 years, 52.2% of whom were me...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:10.1016/j.pneumo.2010.12.009
更新日期:2011-10-01 00:00:00
abstract::Pneumonias occupy a prominent situation among lower respiratory tract infections where they are remarkable for their potential mortality and for our relative knowledge of the responsible micro-organisms. Analysis and synthesis of each series published must answer several questions, such as: what are the lung diseases ...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
abstract::Perthes syndrome, or traumatic asphyxia syndrome, is a rare clinical entity, associating cyanosis, cervicofacial petechiae and subconjunctival hemorrhage. It is usually secondary to chest trauma, but can occur in any situation of abrupt rise in intrathoracic pressure with closed glottis. In this paper, we present a ca...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:10.1016/j.pneumo.2016.08.002
更新日期:2016-12-01 00:00:00
abstract::Lambert-Eaton syndrome is a myasthenia-like syndrome of paraneoplastic origin which is often associated with anaplastic small-cell lung cancer. It seems to be an autoimmune disease responsible for a deficit of acetylcholine ejection in the motor end plate. On the occasion of two recent cases, we review the clinical, p...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00