Abstract:
OBJECTIVES:The associations between subclinical depressive symptoms, as well specific symptom subscales, on brain structure in aging are not completely elucidated. This study investigated the extent to which depressive symptoms were related to brain volumes in fronto-limbic structures in a sample of middle-aged to older adults. METHOD:Eighty participants underwent structural neuroimaging and completed the Beck Depression Inventory, 2nd Edition (BDI-II), which comprises separate affective, cognitive, and somatic subscales. Gray matter volumes were extracted from the caudal and rostral anterior cingulate, posterior cingulate, hippocampus, and amygdala. Hierarchical regression models examined the relationship between brain volumes and (i) total depressive symptoms and (ii) BDI-II subscales were conducted. RESULTS:After adjusting for total intracranial volume, race, and age, higher total depressive symptoms were associated with smaller hippocampal volume (p = 0.005). For the symptom subscales, after controlling for the abovementioned covariates and the influence of the other symptom subscales, more somatic symptoms were related to smaller posterior cingulate (p = 0.025) and hippocampal (p < 0.001) volumes. In contrast, the affective and cognitive subscales were not associated with brain volumes in any regions of interest. CONCLUSION:Our data showed that greater symptomatology was associated with smaller volume in limbic brain regions. These findings provide evidence for preclinical biological markers of major depression and specifically advance knowledge of the relationship between subclinical depressive symptoms and brain volume. Importantly, we observed variations by specific depressive symptom subscales, suggesting a symptom-differential relationship between subclinical depression and brain volume alterations in middle-aged and older individuals.
journal_name
Aging Ment Healthjournal_title
Aging & mental healthauthors
Szymkowicz SM,Woods AJ,Dotson VM,Porges EC,Nissim NR,O'Shea A,Cohen RA,Ebner NCdoi
10.1080/13607863.2018.1432030subject
Has Abstractpub_date
2019-07-01 00:00:00pages
819-830issue
7eissn
1360-7863issn
1364-6915journal_volume
23pub_type
杂志文章abstract:OBJECTIVES:This paper reports on the acceptability and effectiveness of the FITS (Focussed Intervention Training and Support) into Practice Programme. This intervention was scaled up from an earlier cluster randomised-controlled trial that had proven successful in significantly decreasing antipsychotic prescribing in c...
journal_title:Aging & mental health
pub_type: 评论,杂志文章
doi:10.1080/13607863.2015.1063102
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVES:Dementia is a major and growing health problem. Diagnosis is an important step in the access to care, but many dementia patients remain undiagnosed. This study investigated the magnitude and variation in the difference between 'observed' and 'estimated' prevalence of dementia in general practices. We also ex...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2011.596805
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVES:Effects of two mentally stimulating art interventions on processing speed and visuo-spatial cognition were compared in three samples. METHOD:In a randomized 10-week art intervention study with a pre-post follow-up design, 113 adults (27 healthy older adults with subjective memory complaints, 50 healthy olde...
journal_title:Aging & mental health
pub_type: 杂志文章,随机对照试验
doi:10.1080/13607863.2015.1114587
更新日期:2017-04-01 00:00:00
abstract::Objectives: Providing care for family members with Alzheimer's disease (AD) might awaken ambivalent feelings in caregivers. This topic, however, has received little research attention. Having reliable and valid scales is a first step in expanding our knowledge in this area, particularly among different cultural groups...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2020.1715341
更新日期:2020-01-20 00:00:00
abstract::This paper reviews the proposals from the Lord Chancellor's Department for new Mental Incapacity law for England and Wales as they may impact on older people with dementia. Various concerns and issues are raised, particularly from the perspective of health care professionals, and the focus is the interface between suc...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607860120080279
更新日期:2001-11-01 00:00:00
abstract::Previous studies have examined either coping strategies or defence mechanisms; however, few have considered both. This research examined age differences in the type of defence mechanisms and coping strategies that people employ. In addition, gender differences, personality, and environmental variables were taken into ...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/1360786031000072277
更新日期:2003-03-01 00:00:00
abstract:OBJECTIVES:Care managers and professional caregivers of home care services are sometimes unaware of the psychosocial approaches to the challenging behaviour of dementia. Therefore, we developed a Behaviour Analytics & Support Enhancement (BASE) programme. We investigated the effects of the programme on the attitudes to...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2017.1332160
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVES:Given the chronically painful, incurable nature of osteoarthritis, effective cognitive and behavioral coping strategies may be critical for older adults with the disease. Little is known about how and why coping changes over time, nor about stability of coping strategies in persons with osteoarthritis. The a...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2014.1003286
更新日期:2015-01-01 00:00:00
abstract::Objectives: The relationship between body satisfaction and self-esteem among older women is understudied, in particular the potential mechanisms underlying the relationship. The purpose of this study was to investigate social and temporal comparisons and self-objectification, their relationship to body satisfaction an...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2018.1544222
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVE:There have been few studies examining the relationship between chronic obstructive pulmonary disease (COPD) and psychiatric morbidity in Hong Kong. This study aimed to examine the prevalence of depressive disorders (major depression, dysthymia and adjustment disorder with depressed mood) in Chinese patients w...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2013.856862
更新日期:2014-07-01 00:00:00
abstract::Formal cognitive testing is an integral part of the mental state examination, and we aimed to test whether clinicians were able to predict the score on the mini-mental state examination (MMSE) by watching a conversation between a person and the interviewer about their memory. A total of 41 professionals rated 30 patie...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607860902845566
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:In the past few decades, foreign home care to frail older adults has become a common alternative to family care in many developed countries. Whereas Alzheimer's disease and related dementias (ADRD) are common conditions in this population of frail older adults, little is known about the beliefs of foreign ho...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607860802534625
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVES:Limited health literacy has been shown to be associated with poor health status. However, research to date has not elucidated the factors that mediate the relationship between low literacy and poor health outcomes. The purpose of this study was to examine the mediating effect of self-efficacy on the relation...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607861003801011
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVES:In many countries veterans from World War II are growing old. Research has shown that war experiences continue to impact those who have been involved in war for a long time. The present study targets old injured war veterans from World War II in Finland. The aim of this study was to produce knowledge of the ...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2014.954525
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:Elder abuse and neglect is an increasing concern that adversely affects the health and well-being of older people in most societies. The purpose of this paper is to describe the psycho-social impact of elder mistreatment on the health and well-being of older Korean people living in New Zealand. METHOD:Data ...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2013.814103
更新日期:2014-01-01 00:00:00
abstract::Terminally ill cancer patients and their caregivers experience significant difficulties discussing illness and impending death (herein defined as mortality communication). The current study compares response levels as well as patterns of association between mortality communication and psychological distress among care...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607860802154473
更新日期:2009-01-01 00:00:00
abstract::Objectives: Poor social connections may be associated with poor cognition in older people who are not experiencing mental health problems, and the trajectory of this association may be moderated by cognitive reserve. However, it is unclear whether this relationship is the same for older people with symptoms of depress...
journal_title:Aging & mental health
pub_type: 杂志文章,多中心研究
doi:10.1080/13607863.2018.1506742
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVES:Information and communicative technology (ICT) use is a potential vehicle for improving the psychological well-being (PWB) of older people. We examined the roles of age, frailty, and social connectedness in the relationship between ICT use and PWB. METHOD:Telephone interviews were conducted in mid-2016 with...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2017.1358354
更新日期:2018-11-01 00:00:00
abstract::Objective: We examined: 1. depression rates among senior center clients; and 2. the acceptability of a lay-delivered intervention for depression ("Do More, Feel Better") from the perspective of key stakeholders prior to its implementation.Method: We conducted cross-sectional surveys at four Seattle-area senior centers...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2019.1698515
更新日期:2019-12-04 00:00:00
abstract::Objectives: Emerging evidence suggests that social networks may protect against the development of dementia among older adults. In this study we analysed the association between social networks, the apolipoprotein E (APOE) ε4 allele, and dementia. We also investigated whether there were gender-specific patterns in thi...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2018.1531368
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVES:The aims were to describe longitudinal patterns in terms of perceived ability to use everyday technology (ET) and involvement in everyday activities over five years in older adults with mild cognitive impairment (MCI), and to examine the predictive value of these patterns regarding diagnostic outcomes. METH...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2017.1297361
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:Older people with dementia living in care homes often lack appropriate activities. Although homes are expected to offer a range of activities to meet residents' needs, little is known about what makes activities meaningful for people with dementia. This study explores concepts of meaningful activity, as defi...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607860802343019
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to examine differences in mental health and satisfaction with life in retired men and women depending on experienced unemployment during working life. METHOD:Based on a representative survey, 1396 retirees in the age range of 60-92 years were interviewed face-to-face, assessing two...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2010.508775
更新日期:2011-03-01 00:00:00
abstract::The purpose of this study was to determine how health impairment, socioeconomic status, and social support relate to life satisfaction in later life. Using data from a sample of 320 older adults from The Georgia Centenarian Study, we constructed a structural model of life satisfaction. LISREL analysis was performed to...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607860600638388
更新日期:2006-09-01 00:00:00
abstract:OBJECTIVES:There is a paucity of research on antisocial personality disorder (ASPD) in the geriatric population and the majority of knowledge on the disorder is drawn from young adult samples. Researchers posit that the prevalence of ASPD as well as other personality disorders (PDs) is underestimated among older adults...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2020.1839867
更新日期:2020-10-27 00:00:00
abstract:OBJECTIVES:Although generalized anxiety disorder (GAD) is one of the most prevalent anxiety disorders in older adults, very little is known about the neurobiology of worry, the hallmark symptom of GAD in adults over the age of 60. This study investigated the neurobiology and neural circuitry of worry in older GAD patie...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2015.1109058
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The negative effect of hypertension has overshadowed possible health problems associated with hypotension. The purposes of this study were to describe the prevalence of hypotension in older adults and to determine the association between hypotension and cognitive function, after adjusting for p...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2016.1268093
更新日期:2018-04-01 00:00:00
abstract::Objectives: The purpose of this study was to validate the Chinese version of the Brief Aging Perception Questionnaire (B-APQ) for older persons with chronic disease living in Taiwan.Methods: This study recruited older patients with chronic diseases from outpatient departments of a medical center in southern Taiwan. Fi...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2020.1734914
更新日期:2020-03-05 00:00:00
abstract::The WM training protocol proposed by Borella et al. found specific and transfer effects among seniors, however, the studies were carried out in the same socio-cultural context and variations in the procedure were never tested. The present study aimed at analyzing the efficacy of Borella et al.'s training, in terms of ...
journal_title:Aging & mental health
pub_type: 杂志文章,随机对照试验
doi:10.1080/13607863.2018.1531372
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:We examined the prospective effects of an evidence-based exercise intervention on depressive symptoms in older Hispanics/Latinos and the potential synergistic effects (if any) of an attribution-retraining component to counter negative ascriptions to the aging process. METHOD:We analyzed baseline, 1-, 12-, 2...
journal_title:Aging & mental health
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1080/13607863.2018.1450833
更新日期:2019-06-01 00:00:00