Is the ICH score a valid predictor of mortality in intracerebral hemorrhage?

Abstract:

PURPOSE:The intracerebral hemorrhage (ICH) score utilizes a 0- to 6-point scoring system to predict 30-day mortality in ICH patients. The purpose of this analysis was to (a) validate the ICH score in an international, heterogeneous population of ICH patients; and (b) assess the usefulness of a 72-h ICH score. DATA SOURCES:Analyses were based on data from 399 patients in the Novo Nordisk trial F7ICH-1371. The ICH score's ability to predict mortality was determined by calculating the sensitivity, specificity, and positive predictive value (PPV). CONCLUSIONS:Both the baseline and 72-h ICH score had high specificity but low sensitivity resulting in an overall PPV of 57%-76%. Specificity of the ICH score was higher in the baseline ICH score (95%) as compared to the 72-h score (89%). Sensitivity of the ICH score was higher in the 72-h ICH score (75%) as compared to the baseline score (36%). IMPLICATIONS FOR PRACTICE:The baseline ICH score provides reasonable PPV while the 72-h score provides higher sensitivity. ICH scores obtained at baseline and/or 72 h are valid and may help practitioners to more accurately predict 30-day mortality in ICH patients.

journal_name

J Am Assoc Nurse Pract

authors

Meyer DM,Begtrup K,Grotta JC,Recombinant Activated Factor VII Intracerebral Hemorrhage Trial Investigators.

doi

10.1002/2327-6924.12198

subject

Has Abstract

pub_date

2015-07-01 00:00:00

pages

351-5

issue

7

eissn

2327-6886

issn

2327-6924

journal_volume

27

pub_type

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