Abstract:
PURPOSE:The intracerebral hemorrhage (ICH) score utilizes a 0- to 6-point scoring system to predict 30-day mortality in ICH patients. The purpose of this analysis was to (a) validate the ICH score in an international, heterogeneous population of ICH patients; and (b) assess the usefulness of a 72-h ICH score. DATA SOURCES:Analyses were based on data from 399 patients in the Novo Nordisk trial F7ICH-1371. The ICH score's ability to predict mortality was determined by calculating the sensitivity, specificity, and positive predictive value (PPV). CONCLUSIONS:Both the baseline and 72-h ICH score had high specificity but low sensitivity resulting in an overall PPV of 57%-76%. Specificity of the ICH score was higher in the baseline ICH score (95%) as compared to the 72-h score (89%). Sensitivity of the ICH score was higher in the 72-h ICH score (75%) as compared to the baseline score (36%). IMPLICATIONS FOR PRACTICE:The baseline ICH score provides reasonable PPV while the 72-h score provides higher sensitivity. ICH scores obtained at baseline and/or 72 h are valid and may help practitioners to more accurately predict 30-day mortality in ICH patients.
journal_name
J Am Assoc Nurse Practauthors
Meyer DM,Begtrup K,Grotta JC,Recombinant Activated Factor VII Intracerebral Hemorrhage Trial Investigators.doi
10.1002/2327-6924.12198subject
Has Abstractpub_date
2015-07-01 00:00:00pages
351-5issue
7eissn
2327-6886issn
2327-6924journal_volume
27pub_type
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