Abstract:
:With the advent and increased use of chemotherapeutic agents and radiation therapy, cancer survival rates have increased. With increased survival, both acute and chronic cardiotoxic adverse effects have emerged. The growing need for managing the treatment of individuals with chemotherapy-induced cardiotoxicity has led to the formation of cardio-oncology programs throughout the United States. These programs concentrate on many aspects of cardiac disease in the oncology patient. Of these, the cardiotoxic effects (particularly cardiomyopathy) of anthracyclines and HER2 receptor inhibitors are a large focus of cardio-oncology practice. Despite the increasing availability of these programs, no consensus guidelines have been established to provide a framework for treating these patients. This review describes the initial evaluation, risk assessment, and management of individuals receiving anthracycline and HER2 receptor inhibitor therapy for cardiomyopathy. These recommendations are supported by the current literature in this field.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Jahangir E,Shah S,Shum K,Baxter C,Fitzpatrick JD,Cole J,Gilliland Y,Polin NMdoi
10.14423/SMJ.0000000000000232subject
Has Abstractpub_date
2015-02-01 00:00:00pages
71-8issue
2eissn
0038-4348issn
1541-8243pii
SMJ14188journal_volume
108pub_type
杂志文章,评审abstract::We have reported a case of septicemia and meningitis due to alpha-hemolytic Streptococcus in a 5-day-old infant. The microbiologic and clinical characteristics of neonatal infection with this organism lead us to conclude that this bacterium can be pathogenic in the newborn and should not be dismissed as a contaminant....
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198303000-00032
更新日期:1983-03-01 00:00:00
abstract::Coronary heart disease remains the major cause of mortality and morbidity in the United States and other western countries despite major advances in its treatment. During the last decades, many markers of coronary artery disease have been found which help predict future risk of cardiovascular events. High-sensitivity ...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/SMJ.0b013e31816c0195
更新日期:2008-05-01 00:00:00
abstract::Extramural programs may be evaluated in terms of effectiveness in achieving their particular goals. The components of structure, process, and outcome are examined as related sets of program elements. Goals influence appropriate structure in organization, facilities, and manpower. Structure in turn influences process o...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197906000-00027
更新日期:1979-06-01 00:00:00
abstract::We prospectively studied preoperative and postoperative grip and pinch strength in 21 patients having 30 consecutive median nerve decompressions for carpal tunnel syndrome. All procedures were done by one surgeon. Each hand operated on served as its own control and was studied by the same therapist preoperatively and ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199209000-00009
更新日期:1992-09-01 00:00:00
abstract::This is a prospective clinical study of 41 consecutive patients with isolated tears of the medial meniscus who underwent meniscectomy by conventional arthrotomy. The results are presented in terms of length of hospitalization, complications, analgesic requirements during hospitalization, and ability to regain muscle c...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198309000-00021
更新日期:1983-09-01 00:00:00
abstract::Two patients receiving steroid therapy for sarcoidosis had a potentially fatal opportunistic infection that was difficult to differentiate from the underlying illness, but was successfully treated after the diagnosis was made. The effects of sarcoidosis on the immune system and the additional effects of steroid therap...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::Since April 1975, 292 patients have had gastric operations for morbid obesity: gastric bypass with Roux-en-Y gastrojejunostomy (RY), 105 patients; gastric bypass with loop gastrojejunostomy (loop), 69 patients; greater curvature gastroplasty, 40 patients; and gastric partition with gastrogastrostomy, 78 patients. Foll...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198211000-00005
更新日期:1982-11-01 00:00:00
abstract::A patient with stable non-insulin-dependent diabetes mellitus had five successive cranial nerve palsies, all of which resolved. This syndrome is rarely encountered in patients with diabetes and in otherwise healthy individuals. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198502000-00027
更新日期:1985-02-01 00:00:00
abstract::Pregnancy is an unusual occurrence in women with ESRD. We report a successful pregnancy in a patient with ESRD who was receiving hemodialysis; she gave birth to a healthy female infant at 34 weeks' gestational age. We discuss possible physiologic causes of gonadal dysfunction in patients with ESRD. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199102000-00033
更新日期:1991-02-01 00:00:00
abstract::Primary malignant melanoma of the oral cavity is uncommon. Four cases are presented. The average age is in the sixth decade. Early diagnosis is difficult and prognosis is generally poor. Efforts toward earlier detection and treatment are recommended. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198002000-00045
更新日期:1980-02-01 00:00:00
abstract::The use of stress echocardiography (SE) in an elderly population was retrospectively evaluated and compared with myocardial perfusion scintigraphy (MPS) in a similar group. Patients > or = 80 years of age were evaluated by treadmill or pharmacologic SE (group 1; n = 65) to determine its predictive value for cardiac ev...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199612000-00007
更新日期:1996-12-01 00:00:00
abstract::Diagnosis and management of hand infections in the elderly can be challenging. The general principles of rest, elevation, compresses, and drainage when appropriate apply. Antibiotics are important to therapy. Review of data from elderly patients and comparison with a younger population having identical infections show...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198502000-00009
更新日期:1985-02-01 00:00:00
abstract::This article describes various surgical technics commonly used for reconstructing the deep femoral artery. The applicability, advantages, and disadvantages of various methods also are discussed. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197708000-00013
更新日期:1977-08-01 00:00:00
abstract:OBJECTIVES:The National Lung Screening Trial (NLST) demonstrated a 20% reduction in mortality with low-dose computed tomography (CT) for lung cancer screening (LCS). The NLST found the greatest benefit to LCS for patients who underwent annual screening for a full 3-year follow-up period. The adherence to serial imaging...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000001167
更新日期:2020-11-01 00:00:00
abstract::We report a case of recurrent Merkel cell carcinoma (MCC) of the upper extremity, treated aggressively with wide local excision, regional lymphadenectomy, and immediate reconstruction. Five years after surgery, there is no clinical or diagnostic evidence of locoregional recurrence or distant disease. The patient's upp...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00
abstract:OBJECTIVES:Anemia, either chronic or newly developed in the hospital as a result of underlying disease and/or phlebotomy, is seen commonly among general medical inpatients, and its impact on the quality and efficiency of care is unknown. METHODS:This study investigated the relation among hemoglobin level, length of st...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e318290f930
更新日期:2013-05-01 00:00:00
abstract::We have described a patient with long-standing chronic granulocytic leukemia. Although most patients with this disorder eventually have a picture of acute leukemia (blast crisis), this patient had massive thrombocytosis (platelet count greater than 5.000 x 10(9)/L) without major symptoms, but he died after transfusion...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198804000-00029
更新日期:1988-04-01 00:00:00
abstract::We have reported a case of horseshoe kidney, a common renal fusion anomaly. Because of the 25% incidence of associated genitourinary anomalies, we believe that the diagnosis of horseshoe kidney in pediatric patients should initiate a thorough urologic evaluation, including intravenous urography and real-time sonograph...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198502000-00021
更新日期:1985-02-01 00:00:00
abstract::Thirteen male patients consecutively admitted to an inpatient drug and alcohol rehabilitation hospital with the primary diagnosis of crack cocaine dependence were shown a 30-minute videotape that included salient environmental cues intended to elicit cocaine craving. The subjects were tested before and after the video...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199411000-00016
更新日期:1994-11-01 00:00:00
abstract::Chronic mucocutaneous candidiasis is a heterogeneous group of immunodeficiencies associated with persistent candidal infections. Patients with chronic mucocutaneous candidiasis are rarely associated with systemic infections caused by other fungi, but almost never by Candida. The authors report a case of a 16-year-old ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-200408000-00024
更新日期:2004-08-01 00:00:00
abstract::Bile acid sequestrants (BAS) continue to command a position in the treatment of dyslipidemias 25 years after their introduction. Partial diversion of the enterohepatic circulation using BAS depletes the endogenous bile acid pool by approximately 40%, thus stimulating an increase in bile acid synthesis from cholesterol...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/01.smj.0000208120.73327.db
更新日期:2006-03-01 00:00:00
abstract:BACKGROUND:Hyponatremia is a frequent condition in elderly patients. In diagnostic workup, a 24-hour urine sample is used to measure urinary osmolality and urinary sodium concentration necessary to confirm the diagnosis of the syndrome of inappropriate secretion of antidiuretic hormone (SIADH). This study was undertake...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e31819b0e06
更新日期:2009-04-01 00:00:00
abstract::A case of perforation and bleeding from a diverticulum of the second portion of the duodenum in a patient with recurrent pancreatitis is presented. Upper gastrointestinal roentgenogram revealed an abnormal tract and retroperitoneal air arising from the diverticulum. The fistulous tract communicated with pancreas. Blee...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197706000-00037
更新日期:1977-06-01 00:00:00
abstract::We have described a case of cyclic neutropenia and pregnancy. Although many such cases exist, we believe this is the first time the association has been documented. In this patient, pregnancy had a mitigating effect on the symptoms caused by cyclic neutropenia. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198804000-00031
更新日期:1988-04-01 00:00:00
abstract::Prosthetic joint infection with Mycobacterium tuberculosis usually involves the hips or knees and can result from either local reactivation, or less often from hematogenous spread. Predisposing conditions include rheumatoid arthritis, chronic steroid use and pulmonary diseases. The most common symptom at presentation ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000232972.50186.4c
更新日期:2007-01-01 00:00:00
abstract::In 32 patients with the onset of myasthenia gravis after age 50, myasthenic crisis occurred in 53% and persisted for a mean of 33 days (range six to 84 days). Three of the patients had a second crisis. Precipitating factors were found in 60% of the episodes. Treatment of 20 episodes of crisis resulted in excellent rec...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198510000-00017
更新日期:1985-10-01 00:00:00
abstract::A three-year prospective study during the entire course of preventive therapy with isoniazid (INH) for recently infected hospital employees was undertaken to evaluate the risk of developing INH-related hepatic injury. Results of clinical and laboratory tests at 1, 2, 6, and 12 months were correlated to ascertain the s...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197702000-00009
更新日期:1977-02-01 00:00:00
abstract::The term "top of the basilar" has been used in reference to a group of signs and symptoms of midbrain, diencephalic, and posteroinferior hemispheric dysfunction. It has been attributed to ischemia in the territory of second- and third-order vessels that arise from the uppermost portion of the basilar artery. We report...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198807000-00009
更新日期:1988-07-01 00:00:00
abstract::A case of carcinoma of the ampulla of Vater was diagnosed preoperatively by percutaneous transhepatic cholangiography using the Chiba needle. A dilated pancreatic duct is a radiologic sign diagnostic of early ampullary carcinoma. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197912000-00051
更新日期:1979-12-01 00:00:00
abstract::Semiquantitative amniotic fluid volume (AFV) determination is a component of the fetal biophysical profile (BPP). To assess decreased AVF we did BPPs of 174 fetuses within 1 week of delivery. Two methods were used: measurement of the single largest vertical pocket (oligohydramnios = depth < 1 cm) and the four-quadrant...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199304000-00011
更新日期:1993-04-01 00:00:00