Characteristics of computed tomography perfusion parameters in non-small-cell-lung-cancer and its relationship to histology, size, stage an treatment response.

Abstract:

OBJECTIVES:To analyze computed tomography perfusion (CTP) parameters in NSCLC. MATERIALS AND METHODS:Prospective study, 152 patients with NSCLC. CTP parameters were correlated with histology, stage, size and response to conventional chemotherapy/radiotherapy. RESULTS:Neuroendocrine tumours presented higher BV (p 0.002). Negative correlation of PMB (p 0.003) and positive of MTT (p 0.046) with T stage was found. BF showed negative correlation with size. No differences were found with the RECIST levels of response to chemotherapy/radiotherapy. CONCLUSIONS:CTP parameters were highly variable. Neuroendocrine tumours presented higher BV and PMB values. Perfusion parameters do not differ depending on the stage and do not predict response to treatment.

journal_name

Clin Imaging

journal_title

Clinical imaging

authors

Trinidad López C,Souto Bayarri M,Oca Pernas R,Delgado Sánchez-Gracián C,González Vázquez M,Vaamonde Liste A,Tardáguila De La Fuente G,De La Fuente Aguado J

doi

10.1016/j.clinimag.2017.12.001

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

5-12

eissn

0899-7071

issn

1873-4499

pii

S0899-7071(17)30247-4

journal_volume

50

pub_type

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