Abstract:
:The study was conducted to explore the modulatory effects of chlorpyrifos and protective role of vitamin C in tissues of Clarias batrachus. Treatments include E1 group (basal diet plus 1.65mgL(-1) CPF) and E2 group (basal diet+200mgkg body weight vitamin C and 1.65mgL(-1) CPF) along with a control group of fishes (fed on basal diet only). After 1, 7, 15, and 30d of treatment, fish tissues (brain, blood and liver) were used for the estimation of growth, biochemical and haematological parameters. The results of E1 group indicated significantly lower weight gain and survival rate. Brain AChE activity was inhibited. The RBC, Hb, respiratory burst activity, total protein and HSI were also reduced whereas WBC count, plasma glucose and haematocrit were elevated. In contrast, liver glycogen content, lactate dehydrogenase, alkaline and acid phosphatase activities were inhibited and malate dehydrogenase, aspartate, alanine amino transferase were enhanced. The E2 group of fish exhibited significant improvement in growth, survival, haematological indices, brain AChE, liver glycogen and oxidative enzyme activity. The findings support that dietary vitamin C supplementation might be helpful in abrogation of chlorpyrifos toxicity and improves growth, survival, biochemical and haematological conditions in fishes.
journal_name
Chemospherejournal_title
Chemosphereauthors
Narra MR,Rajender K,Rudra Reddy R,Rao JV,Begum Gdoi
10.1016/j.chemosphere.2015.03.006subject
Has Abstractpub_date
2015-08-01 00:00:00pages
172-8eissn
0045-6535issn
1879-1298pii
S0045-6535(15)00206-4journal_volume
132pub_type
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