当前位置： SCI文献检索 > JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY期刊下所有文献 > Chronic performance of a leadless cardiac pacemaker: 1-year follow-up of the LEADLESS trial.

Chronic performance of a leadless cardiac pacemaker: 1-year follow-up of the LEADLESS trial.

Abstract：

BACKGROUND:A leadless cardiac pacemaker (LCP) system was recently introduced to overcome lead-related complications of conventional pacing systems. To date, long-term results of an LCP system are unknown. OBJECTIVES:The aim of this study was to assess the complication incidence, electrical performance, and rate response characteristics within the first year of follow-up of patients implanted with an LCP. METHODS:We retrospectively assessed intermediate-term follow-up data for 31 of 33 patients from the LEADLESS trial cohort who had an indication for single-chamber pacing and received an LCP between December 2012 and April 2013. RESULTS:The mean age of the cohort was 76 ± 8 years, and 65% were male. Between 3 and 12 months of follow-up, there were no pacemaker-related adverse events reported. The pacing performance results at 6- and 12-month follow-up were, respectively, as follows: mean pacing threshold (at a 0.4-ms pulse width), 0.40 ± 0.26 V and 0.43 ± 0.30 V; R-wave amplitude 10.6 ± 2.6 mV and 10.3 ± 2.2 mV; and impedance 625 ± 205 Ω and 627 ± 209 Ω. At the 12-month follow-up in 61% of the patients (n = 19 of 31), the rate response sensor was activated, and an adequate rate response was observed in all patients. CONCLUSIONS:The LCP demonstrates very stable performance and reassuring safety results during intermediate-term follow-up. These results support the use of the LCP as a promising alternative to conventional pacemaker systems. Continued evaluation is warranted to further characterize this system. (Evaluation of a New Cardiac Pacemaker; NCT01700244).

journal_name

J Am Coll Cardiol

journal_title

Journal of the American College of Cardiology

authors

Knops RE,Tjong FV,Neuzil P,Sperzel J,Miller MA,Petru J,Simon J,Sediva L,de Groot JR,Dukkipati SR,Koruth JS,Wilde AA,Kautzner J,Reddy VY

doi

10.1016/j.jacc.2015.02.022

subject

Has Abstract

pub_date

2015-04-21 00:00:00

pages

1497-504

issue

15

eissn

0735-1097

issn

1558-3597

pii

S0735-1097(15)00609-9

journal_volume

65

pub_type

临床试验,杂志文章,多中心研究

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