Abstract:
OBJECTIVE:To determine the prevalence of overweight/obese status in children with autism spectrum disorders (ASD), identify associated characteristics, and develop a model to predict weight status. METHODS:The prevalence of overweight and obesity was determined in 2769 children with ASD enrolled in the Autism Speaks Autism Treatment Network, a collaboration of 17 academic centers, and compared with a national sample matched for age, sex, and race. Associations in the ASD sample between weight status and demographic and clinical variables, such as age, race, head circumference, and adaptive functioning, were tested using ordinal logistic regression. The accuracy of a final model that predicted weight status based on early life variables was evaluated in a validation sample. RESULTS:The prevalence of overweight and obesity were 33.9% and 18.2%, respectively; ASD was associated with a higher risk of obesity (but not overweight) relative to the national sample (odds ratio [OR], 1.16; 95% confidence interval [CI], 1.05-1.28; P = .003). In the adjusted analysis, overweight/obese status was significantly associated with Hispanic ethnicity (OR, 1.99; 95% CI, 1.37-2.89), parental high school education (OR, 1.56; 95% CI, 1.09-2.21), high birth weight (OR, 1.56; 95% CI, 1.11-2.18), macrocephaly (OR, 4.01; 95% CI, 2.96-5.43), and increased somatic symptoms (OR, 1.41; 95% CI, 1.01-1.95). A prediction model designed to have high sensitivity predicted low risk of overweight/obesity accurately, but had low positive predictive value. CONCLUSIONS:The prevalence of obesity in children with ASD was greater than a national sample. Independent associations with increased weight status included known risk factors and macrocephaly and increased level of somatic symptoms. A model based on early life variables accurately predicted low risk of overweight/obesity.
journal_name
Acad Pediatrjournal_title
Academic pediatricsauthors
de Vinck-Baroody O,Shui A,Macklin EA,Hyman SL,Leventhal JM,Weitzman Cdoi
10.1016/j.acap.2015.03.008subject
Has Abstractpub_date
2015-07-01 00:00:00pages
396-404issue
4eissn
1876-2859issn
1876-2867pii
S1876-2859(15)00079-0journal_volume
15pub_type
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journal_title:Academic pediatrics
pub_type: 杂志文章,评审
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更新日期:2013-11-01 00:00:00
abstract:OBJECTIVE:An innovative low-cost parenting intervention, implemented through health services in Jamaica showed benefits to children's cognitive development at 18 months and parent's attitudes concerning childcare. We assessed the impact of the intervention on child and parent outcomes at 6 years of age. METHODS:A clus...
journal_title:Academic pediatrics
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journal_title:Academic pediatrics
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journal_title:Academic pediatrics
pub_type: 杂志文章
doi:10.1016/j.acap.2018.01.010
更新日期:2018-04-01 00:00:00
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journal_title:Academic pediatrics
pub_type: 杂志文章
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更新日期:2011-07-01 00:00:00
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journal_title:Academic pediatrics
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journal_title:Academic pediatrics
pub_type: 杂志文章
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更新日期:2012-09-01 00:00:00
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journal_title:Academic pediatrics
pub_type: 杂志文章
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更新日期:2017-01-01 00:00:00
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journal_title:Academic pediatrics
pub_type: 杂志文章
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更新日期:2013-05-01 00:00:00
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journal_title:Academic pediatrics
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journal_title:Academic pediatrics
pub_type: 杂志文章
doi:10.1016/j.acap.2018.09.008
更新日期:2019-01-01 00:00:00
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更新日期:2017-01-01 00:00:00
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journal_title:Academic pediatrics
pub_type: 杂志文章
doi:10.1016/j.acap.2010.03.003
更新日期:2010-07-01 00:00:00
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更新日期:2020-03-01 00:00:00
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journal_title:Academic pediatrics
pub_type: 杂志文章
doi:10.1016/j.acap.2018.09.003
更新日期:2019-04-01 00:00:00
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journal_title:Academic pediatrics
pub_type: 杂志文章
doi:10.1016/j.acap.2020.09.016
更新日期:2020-10-07 00:00:00
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journal_title:Academic pediatrics
pub_type: 杂志文章
doi:10.1016/j.acap.2017.08.001
更新日期:2018-01-01 00:00:00
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journal_title:Academic pediatrics
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journal_title:Academic pediatrics
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更新日期:2011-09-01 00:00:00
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journal_title:Academic pediatrics
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journal_title:Academic pediatrics
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更新日期:2020-12-21 00:00:00
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journal_title:Academic pediatrics
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更新日期:2019-01-01 00:00:00
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journal_title:Academic pediatrics
pub_type: 杂志文章
doi:10.1016/j.acap.2017.11.005
更新日期:2018-08-01 00:00:00
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journal_title:Academic pediatrics
pub_type: 杂志文章
doi:10.1016/j.acap.2018.05.007
更新日期:2019-01-01 00:00:00
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journal_title:Academic pediatrics
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doi:10.1016/j.acap.2017.08.005
更新日期:2018-03-01 00:00:00
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journal_title:Academic pediatrics
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journal_title:Academic pediatrics
pub_type: 杂志文章
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更新日期:2010-01-01 00:00:00