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Management of pulmonary arterial hypertension.

Abstract：

:Pulmonary hypertension (PH) is common and may result from a number of disorders, including left heart disease, lung disease, and chronic thromboembolic disease. Pulmonary arterial hypertension (PAH) is an uncommon disease characterized by progressive remodeling of the distal pulmonary arteries, resulting in elevated pulmonary vascular resistance and, eventually, in right ventricular failure. Over the past decades, knowledge of the basic pathobiology of PAH and its natural history, prognostic indicators, and therapeutic options has exploded. A thorough evaluation of a patient is critical to correctly characterize the PH. Cardiac studies, including echocardiography and right heart catheterization, are key elements in the assessment. Given the multitude of treatment options currently available for PAH, assessment of risk and response to therapy is critical in long-term management. This review also underscores unique situations, including perioperative management, intensive care unit management, and pregnancy, and highlights the importance of collaborative care of the PAH patient through a multidisciplinary approach.

journal_name

J Am Coll Cardiol

journal_title

Journal of the American College of Cardiology

authors

McLaughlin VV,Shah SJ,Souza R,Humbert M

doi

10.1016/j.jacc.2015.03.540

subject

Has Abstract

pub_date

2015-05-12 00:00:00

pages

1976-97

issue

18

eissn

0735-1097

issn

1558-3597

pii

S0735-1097(15)01623-X

journal_volume

65

pub_type

杂志文章,评审

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