Abstract：
BACKGROUND:Left atrial (LA) volume has been identified as a predictor of adverse cardiovascular outcomes, both in the general population and in selected clinical conditions. The aim of this study was to evaluate the effect of psoriasis on LA volume and mechanical function. METHODS:A total of 40 consecutive normotensive psoriasis patients free of any cardiovascular disease and 39 healthy volunteers were included. All participants underwent comprehensive transthoracic echocardiographic examination. LA volume and mechanical function were evaluated using real-time three-dimensional echocardiography (RT3DE). RESULTS:There were no significant differences between psoriasis and control groups with regard to conventional echocardiographic parameters. Individuals with psoriasis had a higher incidence of left ventricular diastolic dysfunction (LVDD) than the controls; nine people with psoriasis (23%) and three control individuals (8%) had LVDD (p = 0.06). With regard to the parameters obtained from RT3DE, LA maximum, LA minimum, passive stroke volume, and passive emptying fraction were significantly higher; whereas LA active emptying fraction, LA total emptying fraction, LA expansion index, and active stroke volume values were significantly lower in individuals with psoriasis compared with controls. Disease duration and Psoriasis Area of Severity Index (PASI) score correlated with the majority of volume parameters. CONCLUSION:Individuals with psoriasis had higher LA phasic volumes and impaired LA mechanical function compared with healthy controls. LA volume and functional analysis with RT3DE may facilitate recognition of subtle LA dysfunction in patients with psoriasis.
journal_name
Wien Klin Wochenschrjournal_title
Wiener klinische Wochenschriftauthors
Atas H,Kepez A,Bozbay M,Gencosmanoglu DS,Cincin A,Sunbul M,Bozbay AY,Darvishova R,Ergun Tdoi
10.1007/s00508-015-0817-4subject
Has Abstractpub_date
2015-11-01 00:00:00pages
858-863issue
21-22eissn
0043-5325issn
1613-7671pii
10.1007/s00508-015-0817-4journal_volume
127pub_type
杂志文章abstract：:The decrease in blood viscosity induced by streptokinase (SK) in the present investigation in proportional to the streptokinase concentration up to a concentration of 2000 IE/ml blood. A maximum decrease in viscosity is attained with a dosage of between 200 and 300 IE/ml blood. The decrease in viscosity is already cle...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1977-05-13 00:00:00
abstract：:Selective suppression of the immune system in graft recipients is now achieved in most cases by treatment with cyclosporine A. Due to large individual differences in absorption, utilization and metabolisation of this drug, therapeutic blood levels (immunosuppression/toxicity) can be maintained only by frequent measure...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1986-12-19 00:00:00
abstract：INTRODUCTION:Air insufflation during colonoscopy is considered the standard method in most endoscopic centers. Notably, several studies have reported reduced abdominal pain after colonoscopy with CO2 insufflation in unsedated and in lightly sedated patients. The present study was designed to assess the efficacy of CO2 ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00508-009-1202-y
更新日期：2009-01-01 00:00:00
abstract：:Infections occurring during the early postoperative phase after liver transplantation result in a significant rise in morbidity and mortality. The records of 279 orthoptic transplantations performed in 248 patients were analyzed retrospectively. 55.6% of all patients suffered from one or more episodes of bacterial and...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1996-12-27 00:00:00
abstract：:In Europe at least three human pathogenic species of Borrelia burgdorferi sensu lato are the causative agents of Lyme borreliosis. All three species have been isolated or detected by PCR from skin, CSF and synovial fluid of patients with skin lesions, neuroborreliosis and Lyme arthritis respectively. Studies using str...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：
更新日期：1998-12-23 00:00:00
abstract：:The influence of Cohn fraction II, pepsin- and plasmin-treated gammaglobulin on the opsonization of E. coli 0111 was investigated. Normal serum at different dilutions, as well as serum of patients with different forms of antibody deficiency syndromes were tested. No effect was observed by pre-incubation of the bacteri...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1978-10-27 00:00:00
abstract：:The present study aimed at elucidating lytic effector cell function in 32 schizophrenic patients and comparing the results with data obtained in 27 normal probands. Natural killer cell (NK) activity and antibody dependent cellular cytotoxicity (ADCC) were tested. Schizophrenics did not differ from normal controls in e...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1988-06-10 00:00:00
abstract：:In a prospective study 73 patients on maintenance digitalis treatment at the Paracelsus Institute, Bad Hall, were clinically examined and the dosage of the drug was adjusted according to cardiac symptoms. The clinical effects were correlated to digoxin concentrations measured on the day following admission to hospital...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1979-03-16 00:00:00
abstract：:Hard- and software components offered by different manufacturers are compared with regard to applicability within clinical research projects. The fact that hard- and software have to communicate intensively during A/D conversion is given special attention, and the resulting guidelines for the selection of components a...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1988-11-18 00:00:00
abstract：:Several pathogenic mycoplasma species are known etiologic agents of diseases in man and animals, which typically involve the respiratory tract, urogenital tract and joints and often show chronicity. Although the basis for this chronicity is not well understood, it is apparent that several species of pathogenic mycopla...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：
更新日期：1997-08-08 00:00:00
abstract：:Carnitine was discovered at the beginning of this century, but was nearly forgotten until its importance in fatty acid metabolism was established 50 years later. In the past years, several other functions of carnitine in cellular metabolism have been described. The lung contains more than 40 different cell types, most...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：
更新日期：1996-01-01 00:00:00
abstract：:The possibility of determining the blood levels of antiepileptic drugs represents a considerable advance, under certain circumstances, objective supervision of anticonvulsant therapy. In particular in the case of an unsatisfactory therapeutic result, this procedure helps to reveal the causes of failure (e.g. incorrect...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1979-08-10 00:00:00
abstract：INTRODUCTION:Diagnostic hysteroscopy is the most precise procedure to evaluate diseases involving the uterine cavity. There is, however, only limited data concerning the use of hysteroscopy carried out as an outpatient procedure in patients with postmenopausal bleeding. MATERIALS AND METHODS:In this study we report on...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1999-04-09 00:00:00
abstract：:The most important advances in the surgical management of renal calculi are reviewed and the following current concepts are discussed: operation of the kidney in situ with dorsal muscle-sparing lumbotomy; intrasinusal pyelolithotomy as a modern principle of stone surgery; modern techniques for the localization and rem...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：
更新日期：1978-03-31 00:00:00
abstract：:In a prospective study, 60 patients with allergic rhinoconjunctivitis and/or asthma due to house dust mites were chosen for hyposensitization treatment with Migen (M) or Pharmalgen (P). Immunotherapy stretched over a whole year and every 3 months clinical results were evaluated by the patient's symptom score, by resul...
journal_title：Wiener klinische Wochenschrift
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1989-08-04 00:00:00
abstract：:Self monitoring of blood glucose contributes to the integrated management of diabetes mellitus. It, thus, should be available for all patients with diabetes mellitus type-1 and type-2. Self monitoring of blood glucose improves patients safety, quality of life and glucose control. The current article represents the rec...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-012-0288-9
更新日期：2012-12-01 00:00:00
abstract：BACKGROUND:Primary warm autoimmune hemolytic anemia (WAIHA) is a rare autoimmune disorder frequently responding to corticosteroid first-line treatment and effective second-line treatment options such as splenectomy or anti-CD20 antibody therapy. Disease management is frequently hampered by a lack of evidence. METHODS:...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-015-0863-y
更新日期：2016-04-01 00:00:00
abstract：:Modern techniques in brachyradiotherapy using moulds are described for various tumours of the head and neck. The ideal dose distribution can be calculated by the use of computers and practical examples are shown. The radiobiological and also economical advantages of this method of treatment are discussed. ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1980-02-15 00:00:00
abstract：:Total oesophageal resection for cancer is a major procedure, involving surgery within the thoracic cage, the abdomen and the cervical mediastinum. Plastic restruction using a segment of colon which is placed retrosternally between the cervical oesophagus and the stomach, is an additional procedure of considerable diff...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1975-09-19 00:00:00
abstract：:The therapeutic potential of sodium dichloroacetate (DCA) formerly called vitamin B 15, has already been under investigation for the past few years. The predominant property of DCA underlying its therapeutic action is activation of pyruvate dehydrogenase. The potential therapeutic use of DCA in the treatment of lactic...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：
更新日期：1990-02-02 00:00:00
abstract：:Two-dimensional echocardiography has been shown to be equal, or even superior, to cardiac catheterization in the diagnosis of congenital heart disease. On the basis of clinical and non-invasive investigations alone many cardiac malformations can be diagnosed correctly and an operation carried out without previous cath...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1985-01-04 00:00:00
abstract：BACKGROUND:The 6 min pegboard and ring test (6PBRT) is a valid and reproducible test of unsupported arm exercise endurance. The aim of this study was to determine the associations between the 6PBRT, activities of daily living (ADL) and hemoglobin levels in chronic obstructive pulmonary disease (COPD). METHODS:This stu...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-020-01635-8
更新日期：2020-03-25 00:00:00
abstract：:Tick-borne encephalitis is one of the most frequently-encountered virus diseases of the central nervous system in Europe. Hence, prophylactic measures for the prevention of tick-borne encephalitis are of particular importance, especially since it is virtually impossible to influence the course of the manifest disease ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1976-04-16 00:00:00
abstract：:1. Two examples are given to illustrate the role of dopamine in brain disorders: a) In Parkinson's disease there is a marked deficiency of dopamine in several subcortical brain regions, particularly the striatum (caudate nucleus and putamen) and substantia nigra. This extensive dopaminergic denervation of the basal ga...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：AIM:Guidelines for the management of sepsis have been published but not validated for elderly patients, though a prompt work-up and initiation of appropriate therapy are crucial. This study assesses the impact of a sepsis protocol on timelines for therapy and mortality in standardized management. METHODS:Consecutive p...
journal_title：Wiener klinische Wochenschrift
pub_type： 临床试验,杂志文章
doi：10.1007/s00508-012-0229-7
更新日期：2012-10-01 00:00:00
abstract：:Galactosemia due to uridyl-transferase deficiency was detected in 47 patients between 1/1/1967 and 31/12/1988. The condition took a fulminant course in 31 patients and 10 infants in this group died between the 6th and the 18th day of life. The determination of uridyl-transferase in 36 patients confirmed the diagnosis....
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:Rehabilitation requires the interplay of three essential factors, namely medicine, organization and humanity. The concept of entirety and permanency implies that rehabilitation must commence on the very first day of acute therapy and continue, with the aid of relatives, after discharge from hospital. Depression very f...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1982-01-08 00:00:00
abstract：:Glomerular lesions in lupus nephritis have been extensively studied in recent decades, but much less attention has been paid to the tubulo-interstitial compartment. The aim of this study was to contribute to the understanding of the pathogenesis of tubulo-interstitial lesions in lupus nephritis by analysing their inci...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：2000-08-25 00:00:00
abstract：OBJECTIVE AND METHODS:The aim of the study was to investigate the prevalence of excessive computer game playing behaviour among adolescents with psychopathological tendencies that resemble the classic symptoms of addiction. To address this question, criteria for excessive computer game playing behaviour were developed ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-009-1198-3
更新日期：2009-01-01 00:00:00
abstract：:In end stage congestive heart failure activation of a series of compensatory mechanisms increase renal vascular resistance and impair renal function. Prostaglandin E1 is increasingly used in the treatment of severe heart failure for its vasodilating actions. In various experimental settings prostaglandin E analogues a...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1998-07-31 00:00:00
