Effect of Donor- and Recipient-Related Factors on Arterial Resistance Index After Kidney Transplant.

Abstract:

BACKGROUND:The assessment of color Doppler resistance index (RI) of the intra-renal arteries has been shown to be a good predictor of short-term and long-term graft survival after kidney transplant. In this study, we investigated the influence of donor- and recipient-related factors on RI evaluated early after kidney transplant. METHODS:We prospectively analyzed 90 kidney transplant patients who underwent RI assessment within the first month after the transplant, subdivided into 2 groups according their RI values lower (group A) or higher (group B) than 0.646 (median value). RESULTS:Patients in group A had a lower human leukocyte antigen (HLA) mismatch number (3.3 ± 1 versus 3.9 ± 0.9, P = .007) and were significantly younger (42.8 ± 11 years versus 47.8 ± 11 years, P = .03) than patients in group B. All the others variables examined were not significantly different between the 2 groups. Multivariate logistic regression analysis confirmed that HLA mismatch number (P = .03) and recipient age (P = .03) are independent predictors of RI. CONCLUSIONS:Our data suggest that HLA mismatches and donor age can influence recipient kidney vascular resistance in the early period after transplantation.

journal_name

Transplant Proc

authors

Saracino A,Santarsia G

doi

10.1016/j.transproceed.2015.04.104

subject

Has Abstract

pub_date

2015-09-01 00:00:00

pages

2130-4

issue

7

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(15)00633-8

journal_volume

47

pub_type

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