Increased accumulation of N-isopropyl-p-(123I)-iodoamphetamine in two cases with mitochondrial encephalomyopathy with lactic acidosis and strokelike episodes (MELAS).

Abstract:

:We present two cases with mitochondrial encephalopathy with lactic acidosis and strokelike episodes (MELAS), which showed both increased and decreased accumulation of N-isopropyl-p-(123I)-iodoamphetamine (123I-IMP) in single photon emission computed tomography (SPECT). The increased accumulation of the tracer occurred, before low density appeared on conventional computed tomography, suggesting that 123I-IMP SPECT may be useful in pathophysiological study of MELAS.

journal_name

Neuroradiology

journal_title

Neuroradiology

authors

Morita K,Ono S,Fukunaga M,Yasuda T,Higashi Y,Terao A,Morita R

doi

10.1007/BF00344185

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

358-61

issue

4

eissn

0028-3940

issn

1432-1920

journal_volume

31

pub_type

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