Subcortical frontal lesions on MRI in patients with motor neurone disease.


:MRI was performed in 32 patients with motor neurone disease (26 men and 6 women, aged 40-77 years) and in a control group of 21 subjects. Of the patients studied, 19 had definite and 11 probable amyotrophic lateral sclerosis (ALS) and two had progressive bulbar palsy. In 10 patients there were asymmetrical bilateral foci of increased signal intensity on proton-density and T2-weighted images, confined to the white matter. Two patients had only cortical frontal atrophy and slightly increased ventricular size, whereas 20 had normal MRI. The focal lesions were not confined to corticospinal tracts, but were also observed in subcortical frontal areas. While the lesions along the corticospinal tracts correspond to pyramidal tract degeneration, the subcortical foci correlate with degeneration of the frontal bundles and indicate generalised involvement of the central nervous system.






Andreadou E,Sgouropoulos P,Varelas P,Gouliamos A,Papageorgiou C




Has Abstract


1998-05-01 00:00:00












  • Treatment of elastase-induced intracranial aneurysms in New Zealand white rabbits by use of a novel neurovascular embolization stent device.

    abstract:INTRODUCTION:This study aims to test a novel balloon expandable stent covered with a polytetrafluoroethylene membrane (neurovascular embolization cover (NEC), NFocus Neuromedical, Palo Alto, California) regarding angiographic and histologic aneurysm occlusion. Radiopacity, stent placement, navigation, flexibility, and ...


    pub_type: 杂志文章


    authors: Kühn AL,Roth C,Romeike B,Grunwald IQ

    更新日期:2014-01-01 00:00:00

  • Nasal polyps with metaplastic ossification: CT and MR imaging findings.

    abstract:INTRODUCTION:Metaplastic ossification is a rare event in nasal polyps. The purpose of this study was to review the computed tomography (CT) and magnetic resonance (MR) imaging findings of nasal polyps with metaplastic ossification. METHODS:CT (n=5) and MR (n=3) images of five patients (four men and one woman; mean age...


    pub_type: 杂志文章


    authors: Kim YK,Kim HJ,Kim J,Chung SK,Kim E,Ko YH,Kim ST

    更新日期:2010-12-01 00:00:00

  • Infantile panthalamic infarct with a striking sonographic finding: the "bright thalamus".

    abstract::A "bright thalamus" is not uncommonly observed in cranial sonograms of asphyxiated neonates, but not those of older infants. Three infants, aged 9-14 months, developed acute onset of seizures and disturbance of consciousness after a minor prodromal illness. Bilateral thalamic infarcts were demonstrated by ultrasonogra...


    pub_type: 杂志文章


    authors: Wang HS,Huang SC

    更新日期:1993-01-01 00:00:00

  • Symptomatic spinal epidural lipomatosis without exogenous steroid intake. Report of a case with magnetic resonance imaging.

    abstract::Epidural lipomatosis may be unassociated with steroid use and should be considered in the differential diagnosis of lumbar radiculopathy. This may cause widening of the spinal canal on plain film and complete block on myelography. CT or MRI is diagnostic. ...


    pub_type: 杂志文章


    authors: Gero BT,Chynn KY

    更新日期:1989-01-01 00:00:00

  • PHACES syndrome: a review of eight previously unreported cases with late arterial occlusions.

    abstract::PHACE and PHACES are acronyms for a syndrome of variable expression comprising posterior cranial fossa malformations, facial haemangiomas, arterial anomalies, aortic coarctation and other cardiac disorders, ocular abnormalities and stenotic arterial disease. We review five girls and three boys aged 1 month-14 years wi...


    pub_type: 杂志文章


    authors: Bhattacharya JJ,Luo CB,Alvarez H,Rodesch G,Pongpech S,Lasjaunias PL

    更新日期:2004-03-01 00:00:00

  • Axial diffusivity is increased in the degenerating superior cerebellar peduncles of Friedreich's ataxia.

    abstract:INTRODUCTION:Decreased fractional anisotropy (FA) demonstrated by diffusion tensor MR imaging (DTI) in areas of white matter (WM) damage is generally associated with increase of radial diffusivity, while axial diffusivity is reported to be decreased, unchanged, or increased. Aiming to better define the type of axial di...


    pub_type: 杂志文章


    authors: Della Nave R,Ginestroni A,Diciotti S,Salvatore E,Soricelli A,Mascalchi M

    更新日期:2011-05-01 00:00:00

  • The intersubject and intrasubject reproducibility of FMRI activation during three encoding tasks: implications for clinical applications.

    abstract::The goal of the present study was to evaluate the inter- and intrasubject reproducibility of FMRI activation for three memory encoding tasks previously used in the context of presurgical functional mapping. The primary region of interest (ROI) was the medial temporal lobe (MTL). Comparative ROIs included the inferior ...


    pub_type: 杂志文章


    authors: Harrington GS,Tomaszewski Farias S,Buonocore MH,Yonelinas AP

    更新日期:2006-07-01 00:00:00

  • Positional MRI: a technique for confirming the site of leakage in cerebrospinal fluid rhinorrhoea.

    abstract::We report confirmation of the site of leakage in two patients with spontaneous cerebrospinal fluid (CSF) rhinorrhoea by demonstrating CSF leaking on MRI. Both patients had midline anterior cranial fossa floor (cribriform plate/fovea ethmoidalis) dural-bone defects with arachnoid herniation with or without brain hernia...


    pub_type: 杂志文章


    authors: Gupta V,Goyal M,Mishra NK,Sharma A,Gaikwad SB

    更新日期:1997-11-01 00:00:00

  • Computer-assisted three-dimensional reconstruction of the corticospinal system as a reference for CT and MRI.

    abstract::We present a three-dimensional (3D) anatomical computer-graphics model of the corticospinal system acquired from equidistant serial anatomical slices of six intracranially-fixed human brains. This model is part of a neuroanatomical reference system (NeuRef) which enables 3D visualization of the brain and shows the rel...


    pub_type: 杂志文章


    authors: Buhmann C,Kretschmann HJ

    更新日期:1998-09-01 00:00:00

  • A case of spinal paraganglioma.

    abstract::The neuroradiologic finding of a paraganglioma in the vertebral canal is described here for the first time. These tumors occur more frequently than was previously presumed. Similarities with paragangliomas in the craniocervical region are apparent on angiograms. We consider angiography to be indicated when, in associa...


    pub_type: 杂志文章


    authors: Solymosi L,Ferbert A

    更新日期:1985-01-01 00:00:00

  • In vitro delineation of human brain-stem anatomy using a small resonator: correlation with macroscopic and histological findings.

    abstract::Our purpose was to investigate the potential of an experimental animal coil using a commercial MRI unit to delineate the anatomical structure of the human brain stem. Three formaldehyde-fixed brain-stem specimens were examined by MRI and sectioned perpendicular to their longitudinal axis. The images were compared with...


    pub_type: 杂志文章


    authors: Mäurer J,Mitrovic T,Knollmann FD,Lüdtke E,Requardt H

    更新日期:1996-04-01 00:00:00

  • Spontaneous dissection of the anterior inferior cerebellar artery.

    abstract::A patient presented with the clinical features of a brain stem infarct. MRI confirmed changes of infarction but also revealed an unusual lesion in the left cerebellopontine angle cistern. The evolution of this lesion on MRI, together with angiographic changes, indicated a dissecting aneurysm of the left anterior infer...


    pub_type: 杂志文章


    authors: Hancock JH,Millar JS

    更新日期:2000-07-01 00:00:00

  • Peripheral cerebral aneurysm associated with a glioma.

    abstract::This 42-year-old man with acute subarachnoid, intraventricular and parenchymal hemorrhage from an angiographically and surgically confirmed successfully clipped, right splenial artery aneurysm, subsequently manifested a grade 3 astrocytoma at the site of the aneurysm. Intracranial aneurysms are recognized in associati...


    pub_type: 杂志文章


    authors: Barker CS

    更新日期:1992-01-01 00:00:00

  • Two rare lumbar tumours with unusual MRI characteristics.

    abstract::We present two rare lumbar lesions with similar MRI features: high signal on T1-weighted and proton density images and low signal on T2-weighted images; a melanotic schwannoma, and a giant-cell tumour-like lesion. Melanin in the first case and haemosiderin and metahaemoglobin in the second were responsible for the MRI...


    pub_type: 杂志文章


    authors: Aprile I,Scott CA,Cervesato D,Beltrami CA,Meo A,Fabris G

    更新日期:2000-06-01 00:00:00

  • Cerebellar involvement in metabolic disorders: a pattern-recognition approach.

    abstract::Inborn errors of metabolism can affect the cerebellum during development, maturation and later during life. We have established criteria for pattern recognition of cerebellar abnormalities in metabolic disorders. The abnormalities can be divided into four major groups: cerebellar hypoplasia (CH), hyperplasia, cerebell...


    pub_type: 杂志文章,评审


    authors: Steinlin M,Blaser S,Boltshauser E

    更新日期:1998-06-01 00:00:00

  • Neck-bridge device for combined endovascular and surgical treatment of a giant anterior communicating artery aneurysm.

    abstract::We report the case of a 58-year-old man with a giant partially thrombosed anterior communicating artery aneurysm, which presented with mass effect. Our treatment strategy consisted of endovascular aneurysm circulatory exclusion prior to surgical resection. To do so, we first occluded both the two A1 segments and the a...


    pub_type: 杂志文章


    authors: Mounayer C,Undrén P,Piotin M,Boissonnet H,Moret J

    更新日期:2005-04-01 00:00:00

  • The persistent trigeminal artery: development, imaging anatomy, variants, and associated vascular pathologies.

    abstract::The persistent trigeminal artery (PTA) is the most common and most cephalad-located embryological anastomosis between the developing carotid artery and vertebrobasilar system to persist into adulthood. As such, it is frequently reported as an incidental finding in computed tomography angiography and magnetic resonance...


    pub_type: 杂志文章,评审


    authors: Meckel S,Spittau B,McAuliffe W

    更新日期:2013-01-01 00:00:00

  • NMR anatomy of the brain using inversion-recovery sequences.

    abstract::The use of NMR inversion-recovery (IR) sequences to demonstrate brain anatomy is illustrated. The high level of grey-white matter contrast is of value in localising anatomical structures and demonstrating myelination during childhood. While the resemblance of IR scans to gross anatomical sections in different planes i...


    pub_type: 杂志文章


    authors: Simmonds D,Banks LM,Steiner RE,Young IR

    更新日期:1983-01-01 00:00:00

  • Is contrast-enhanced CT indicated in acute head injury?

    abstract::The authors discuss the value of intravenous contrast enhancement in CT scanning in acute head injury. In a series of seventy consecutive patients they conclude that no incremental information was obtained by performing contrast-enhanced CT scans in the acute phase of the head injury. ...


    pub_type: 杂志文章


    authors: Mauser HW,van Nieuwenhuizen O,Veiga-Pires JA

    更新日期:1984-01-01 00:00:00

  • Syndesmo-odontoid joint and calcium pyrophosphate dihydrate deposition disease (CPPD).

    abstract::Twenty-seven patients with definite or probable CPPS have been investigated with systematic frontal and lateral tomograms of the cervicooccipital region. In 12 cases there were calcifications of the syndesmo-odontoid region. These calcifications are of two different types: linear calcifications (5 cases) and mottled c...


    pub_type: 杂志文章


    authors: Dirheimer Y,Bensimon C,Christmann D,Wackenheim C

    更新日期:1983-01-01 00:00:00

  • Chronic subdural hematoma: correlation of computerized tomography with colour.

    abstract::The computerized tomographic and operative findings in 10 patients with chronic subdural hematoma (SDH) are reviewed. A constant correlation was found between the CT density and the colour of the hematoma evacuated thus enabling an accurate prediction of the colour of fluid one would expect to find at operation. Certa...


    pub_type: 杂志文章


    authors: Naim-ur-Rahman

    更新日期:1987-01-01 00:00:00

  • Dementia imaging in clinical practice: a European-wide survey of 193 centres and conclusions by the ESNR working group.

    abstract:PURPOSE:Through a European-wide survey, we assessed the current clinical practice of imaging in the primary evaluation of dementia, with respect to standardised imaging, evaluation and reporting. METHODS:An online questionnaire was emailed to all European Society of Neuroradiology (ESNR) members (n = 1662) and non-mem...


    pub_type: 杂志文章,多中心研究


    authors: Vernooij MW,Pizzini FB,Schmidt R,Smits M,Yousry TA,Bargallo N,Frisoni GB,Haller S,Barkhof F

    更新日期:2019-06-01 00:00:00

  • Differences in complication rates among the centres in the SPACE study.

    abstract:INTRODUCTION:Despite the high grade of standardisation of study protocols, there is still room for variability among the centres in specific treatment aspects. We evaluated the treatment risk in stent-protected angioplasty of the carotid versus endarterectomy (SPACE) associated with the specific patient enrollment rate...


    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Fiehler J,Jansen O,Berger J,Eckstein HH,Ringleb PA,Stingele R

    更新日期:2008-12-01 00:00:00

  • Postoperative angiographic control of chronic subdural hematomas in adults.

    abstract::After surgical evacuation of a subdural hematoma there is a constant relationship between the return of the deep veins to the midline, the clinical recovery and the absence of a new subdural collection, even when the anterior cerebral artery remains deviated across the midline. ...


    pub_type: 杂志文章


    authors: Fogel LM,Capesius P,Ludwiczak R,Middleton L,Babin E,Dupuis M

    更新日期:1975-12-19 00:00:00

  • Functioning heterotopic grey matter? Increased blood flow with voluntary movement and sensory stimulation.

    abstract::A 66-year-old woman with a right hemiplegia due to cerebral haemorrhage was found to have heterotopic grey matter in the left frontal and right frontal and parietal lobes. She had no neurological disturbance prior to the haemorrhage. Regional cerebral blood flow (rCBF) was measured by xenon-CT (Xe-CT) in the zones of ...


    pub_type: 杂志文章


    authors: Shimodozono M,Kawahira K,Tanaka N

    更新日期:1995-08-01 00:00:00

  • Magnetic resonance imaging and angiography of the brain in embolic left atrial myxoma.

    abstract::A case of left atrial myxoma presenting exclusively with neurological symptoms, studied with magnetic resonance imaging (MRI) combined with cerebral angiography and computed tomography (CT) is reported. Typical angiographic findings suggested the diagnosis of myxoma. MRI showed multiple ischemic lesions disseminated t...


    pub_type: 杂志文章


    authors: Marazuela M,García-Merino A,Yebra M,Brasa JM,Diego J,Durántez A

    更新日期:1989-01-01 00:00:00

  • MR spectroscopy of cerebral white matter in type 2 diabetes; no association with clinical variables and cognitive performance.

    abstract:INTRODUCTION:Type 2 diabetes (DM2) is associated with cognitive decline, but the pathogenesis of this important complication remains unclear. We investigated whether abnormalities in neuronal metabolism or membrane integrity in normal appearing cerebral white matter are associated with cognitive impairment in patients ...


    pub_type: 杂志文章


    authors: Tiehuis A,van der Meer F,Mali W,Pleizier M,Biessels GJ,Kappelle J,Luijten P

    更新日期:2010-02-01 00:00:00

  • Magnetic resonance imaging in temporal bone fracture.

    abstract::In seven patients with temporal bone fractures examined by both CT and MRI, thin section CT proved superior to MRI in demonstrating the full extent of the fractures and the status of the ossicular chain. MR studies were able to demonstrate fractures, when these fractures contained blood or CSF, and the presence of oss...


    pub_type: 杂志文章


    authors: Zimmerman RA,Bilaniuk LT,Hackney DB,Goldberg HI,Grossman RI

    更新日期:1987-01-01 00:00:00

  • Angiotomography for aneurysms and arteriovenous malformations of the head and neck.

    abstract::Angiotomographic studies were performed preoperatively on 201 arterial aneurysms and arteriovenous malformations (AVMs) of the head and neck. There were two extracranial aneurysms, 186 intracranial aneurysms and 13 intracranial AVMs. The equipment used was the Philips NeuroDiagnost, either armed with a single multisec...


    pub_type: 杂志文章


    authors: Sartor K,Nadjmi M

    更新日期:1979-02-26 00:00:00

  • Alcohol percutaneous neurolysis of the sphenopalatine ganglion in the management of refractory cranio-facial pain.

    abstract:INTRODUCTION:The sphenopalatine ganglion (SPN) has been proven to be involved in various types of facial pain syndromes. Management of these cranio-facial pain syndromes can be challenging, and existing specific treatments are sometimes inefficient and may fail. The purpose of this study is to describe and evaluate alc...


    pub_type: 杂志文章


    authors: Kastler A,Cadel G,Comte A,Gory G,Piccand V,Tavernier L,Kastler B

    更新日期:2014-07-01 00:00:00