Variation in the nuclear effects of infection by different human rhinovirus serotypes.

Abstract:

:Human rhinovirus (HRV) is a positive sense RNA virus, which, despite replicating in the cytoplasm, has a significant impact on nuclear transport and nuclear localization of host proteins. A number of studies have identified differences between HRV serotypes, with respect to host response, protease activity and replicative ability. Here we report the sero-specific effects of two group-A HRV serotypes, the minor group HRV2 and the major group HRV16, on nuclear transport and nuclear protein localization. Using Western analysis, immunofluorescence and real time PCR, we show that HRV2 replicates at a faster rate than HRV16, which correlates with earlier production of viral proteases and disruption of host nuclear transport. There is significant variation in the nuclear effects of different rhinovirus species, which in turn may impact disease progression and patient response.

journal_name

Front Microbiol

authors

Walker EJ,Jensen LM,Croft S,Ghildyal R

doi

10.3389/fmicb.2015.00875

subject

Has Abstract

pub_date

2015-08-24 00:00:00

pages

875

issn

1664-302X

journal_volume

6

pub_type

杂志文章
  • Genomic and Functional Characterization of Enterococcus mundtii QAUEM2808, Isolated From Artisanal Fermented Milk Product Dahi.

    abstract::Microbial strains with a unique combination of technological and bioactive properties are preferred for industrial applications. The present study was conducted to evaluate the potential use of Enterococcus mundtii QAUEM2808 (NCBI Accession Number: LSMC00000000) in milk fermentation. This strain was isolated from Dahi...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2019.00434

    authors: Nawaz F,Khan MN,Javed A,Ahmed I,Ali N,Ali MI,Bakhtiar SM,Imran M

    更新日期:2019-03-26 00:00:00

  • B-Vitamin Sharing Promotes Stability of Gut Microbial Communities.

    abstract::Cross-feeding on intermediary and end-point metabolites plays an important role in the dynamic interactions of host-associated microbial communities. While gut microbiota possess inherent resilience to perturbation, variations in the intake of certain nutrients may lead to changes in the community composition with pot...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2019.01485

    authors: Sharma V,Rodionov DA,Leyn SA,Tran D,Iablokov SN,Ding H,Peterson DA,Osterman AL,Peterson SN

    更新日期:2019-07-02 00:00:00

  • Tick Humoral Responses: Marching to the Beat of a Different Drummer.

    abstract::Ticks transmit a variety of human pathogens, including Borrelia burgdorferi, the etiological agent of Lyme disease. Multiple pathogens that are transmitted simultaneously, termed "coinfections," are of increasing importance and can affect disease outcome in a host. Arthropod immunity is central to pathogen acquisition...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章,评审

    doi:10.3389/fmicb.2017.00223

    authors: Oliva Chávez AS,Shaw DK,Munderloh UG,Pedra JH

    更新日期:2017-02-14 00:00:00

  • Potential of Lactic Acid Bacteria Isolated From Different Forages as Silage Inoculants for Improving Fermentation Quality and Aerobic Stability.

    abstract::We aimed at isolating lactic acid bacteria (LAB) from different plant materials to study their crossed-fermentation capacity in silos and to find strains able to confer enhanced aerobic stability to silage. A total of 129 LAB isolates were obtained from lucerne (alfalfa), maize, sorghum, ryegrass, rice, barley, canola...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.586716

    authors: Puntillo M,Gaggiotti M,Oteiza JM,Binetti A,Massera A,Vinderola G

    更新日期:2020-12-08 00:00:00

  • Induction of Escherichia coli Into a VBNC State by Continuous-Flow UVC and Subsequent Changes in Metabolic Activity at the Single-Cell Level.

    abstract::A viable but non-culturable (VBNC) state of bacteria induced by disinfection in water treatment poses serious health risks because of possible resuscitation of VBNC cells during transportation. In this study, a setup using continuous-flow ultraviolet (UVC) irradiation ranging from 0 to 172.2 mJ cm-2 was designed to si...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2018.02243

    authors: Zhang S,Guo L,Yang K,Zhang Y,Ye C,Chen S,Yu X,Huang WE,Cui L

    更新日期:2018-09-25 00:00:00

  • A Pilin Region Affecting Host Range of the Pseudomonas aeruginosa RNA Phage, PP7.

    abstract::The host range of a phage is determined primarily by phage-receptor interaction. Here, we profiled the host range of an RNA leviphage, PP7 that requires functional type IV pilus (TFP) in order to enter into its host bacterium, Pseudomonas aeruginosa. Out of 25 twitching-proficient P. aeruginosa strains, 4 with group I...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2018.00247

    authors: Kim ES,Bae HW,Cho YH

    更新日期:2018-02-16 00:00:00

  • Microbial carbon mineralization in tropical lowland and montane forest soils of Peru.

    abstract::Climate change is affecting the amount and complexity of plant inputs to tropical forest soils. This is likely to influence the carbon (C) balance of these ecosystems by altering decomposition processes e.g., "positive priming effects" that accelerate soil organic matter mineralization. However, the mechanisms determi...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2014.00720

    authors: Whitaker J,Ostle N,McNamara NP,Nottingham AT,Stott AW,Bardgett RD,Salinas N,Ccahuana AJ,Meir P

    更新日期:2014-12-18 00:00:00

  • Porcine Epidemic Diarrhea Virus Shedding and Antibody Response in Swine Farms: A Longitudinal Study.

    abstract::The porcine epidemic diarrhea virus (PEDV) causes an acute and highly contagious enteric disease characterized by severe enteritis, vomiting, watery diarrhea, and a high mortality rate in seronegative neonatal piglets. In the last few years, PED had a large economic impact on the swine industries in Asia and the US, a...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2016.02009

    authors: Bertasio C,Giacomini E,Lazzaro M,Perulli S,Papetti A,Lavazza A,Lelli D,Alborali G,Boniotti MB

    更新日期:2016-12-15 00:00:00

  • The role of adjuvants in therapeutic protection against paracoccidioidomycosis after immunization with the P10 peptide.

    abstract::Paracoccidioidomycosis (PCM), a common chronic mycosis in Latin America, is a granulomatous systemic disease caused by the thermo-dimorphic fungus Paracoccidioides brasiliensis. The glycoprotein gp43 is the main antigen target of P. brasiliensis and a 15-mer internal peptide (QTLIAIHTLAIRYAN), known as P10, defines a ...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2012.00154

    authors: Mayorga O,Muñoz JE,Lincopan N,Teixeira AF,Ferreira LC,Travassos LR,Taborda CP

    更新日期:2012-05-04 00:00:00

  • Population Genomics of Mycobacterium leprae Reveals a New Genotype in Madagascar and the Comoros.

    abstract::Human settlement of Madagascar traces back to the beginning of the first millennium with the arrival of Austronesians from Southeast Asia, followed by migrations from Africa and the Middle East. Remains of these different cultural, genetic, and linguistic legacies are still present in Madagascar and other islands of t...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.00711

    authors: Avanzi C,Lécorché E,Rakotomalala FA,Benjak A,Rapelanoro Rabenja F,Ramarozatovo LS,Cauchoix B,Rakoto-Andrianarivelo M,Tió-Coma M,Leal-Calvo T,Busso P,Boy-Röttger S,Chauffour A,Rasamoelina T,Andrianarison A,Sendrasoa F,Spen

    更新日期:2020-05-11 00:00:00

  • Untangling the fungal niche: the trait-based approach.

    abstract::Fungi are prominent components of most terrestrial ecosystems, both in terms of biomass and ecosystem functioning, but the hyper-diverse nature of most communities has obscured the search for unifying principles governing community organization. In particular, unlike plants and animals, observational studies provide l...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2014.00579

    authors: Crowther TW,Maynard DS,Crowther TR,Peccia J,Smith JR,Bradford MA

    更新日期:2014-10-31 00:00:00

  • Global Proteomic Analysis of the Resuscitation State of Vibrio parahaemolyticus Compared With the Normal and Viable but Non-culturable State.

    abstract::Vibrio parahaemolyticus is a common pathogen which has become a major concern of seafood products. The bacteria in the viable but non-culturable (VBNC) state are unable to form colonies on growth media, but under appropriate conditions they can regain culturability. In this study, V. parahaemolyticus was induced into ...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2019.01045

    authors: Zhong Q,Wang B,Wang J,Liu Y,Fang X,Liao Z

    更新日期:2019-05-08 00:00:00

  • Biphenyl Modulates the Expression and Function of Respiratory Oxidases in the Polychlorinated-Biphenyls Degrader Pseudomonas pseudoalcaligenes KF707.

    abstract::Pseudomonas pseudoalcaligenes KF707 is a soil bacterium which is known for its capacity to aerobically degrade harmful organic compounds such as polychlorinated biphenyls (PCBs) using biphenyl as co-metabolite. Here we provide the first genetic and functional analysis of the KF707 respiratory terminal oxidases in cell...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2017.01223

    authors: Sandri F,Fedi S,Cappelletti M,Calabrese FM,Turner RJ,Zannoni D

    更新日期:2017-06-30 00:00:00

  • Antifungal Effect of Novel 2-Bromo-2-Chloro-2-(4-Chlorophenylsulfonyl)-1-Phenylethanone against Candida Strains.

    abstract::We investigated the antifungal activity of novel a 2-bromo-2-chloro-2-(4-chlorophenylsulfonyl)-1-phenylethanone (compound 4). The synthesis of compound 4 was commenced from sodium 4-chlorobenzene sulfinate and the final product was obtained by treatment of α-chloro-β-keto-sulfone with sodium hypobromite. The sensitivi...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2016.01309

    authors: Staniszewska M,Bondaryk M,Wieczorek M,Estrada-Mata E,Mora-Montes HM,Ochal Z

    更新日期:2016-08-25 00:00:00

  • The Respiratory Microbiome in Cystic Fibrosis: Compartment Patterns and Clinical Relationships in Early Stage Disease.

    abstract::We compared the bacterial microbiomes lodged in the bronchial tree, oropharynx and nose of patients with early stage cystic fibrosis (CF) not using chronic antibiotics, determining their relationships with lung function and exacerbation frequency. CF patients were enrolled in a cohort study during stability and were c...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.01463

    authors: Garcia-Nuñez M,Garcia-Gonzalez M,Pomares X,Montón C,Millares L,Quero S,Prina E,Asensio O,Bosque M,Capilla S,Cuevas O,Monsó E

    更新日期:2020-06-30 00:00:00

  • Diversity and Temporal Dynamics of the Epiphytic Bacterial Communities Associated with the Canopy-Forming Seaweed Cystoseira compressa (Esper) Gerloff and Nizamuddin.

    abstract::Canopy-forming seaweed species of the genus Cystoseira form diverse and productive habitats along temperate rocky coasts of the Mediterranean Sea. Despite numerous studies on the rich macrofauna and flora associated with Cystoseira spp., there is little knowledge about the epiphytic bacteria. We analyzed bacterial pop...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2016.00476

    authors: Mancuso FP,D'Hondt S,Willems A,Airoldi L,De Clerck O

    更新日期:2016-04-08 00:00:00

  • Diversity of Sinorhizobium (Ensifer) meliloti Bacteriophages in the Rhizosphere of Medicago marina: Myoviruses, Filamentous and N4-Like Podovirus.

    abstract::Using different Sinorhizobium meliloti strains as hosts, we isolated eight new virulent phages from the rhizosphere of the coastal legume Medicago marina. Half of the isolated phages showed a very narrow host range while the other half exhibited a wider host range within the strains tested. Electron microscopy studies...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.00022

    authors: Cubo MT,Alías-Villegas C,Balsanelli E,Mesa D,de Souza E,Espuny MR

    更新日期:2020-01-24 00:00:00

  • Corrigendum: The cyl Genes Reveal the Biosynthetic and Evolutionary Origins of the Group B Streptococcus Hemolytic Lipid, Granadaene.

    abstract::[This corrects the article DOI: 10.3389/fmicb.2019.03123.]. ...

    journal_title:Frontiers in microbiology

    pub_type: 已发布勘误

    doi:10.3389/fmicb.2020.00325

    authors: Armistead B,Whidbey C,Iyer LM,Herrero-Foncubierta P,Quach P,Haidour A,Aravind L,Cuerva JM,Jaspan HB,Rajagopal L

    更新日期:2020-02-25 00:00:00

  • Assessment of the Microbiome and Potential Aflatoxin Associated With the Medicinal Herb Platycladus orientalis.

    abstract::Platycladi Semen, which is derived from the dried ripe seed of Platycladus orientalis, has been used for the treatment of insomnia and constipation in China for 2000 years. However, it is susceptible to fungal and aflatoxin contamination under proper humidity and temperature during storage. Although aflatoxin contamin...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.582679

    authors: Yu J,Guo M,Jiang W,Yang M,Pang X

    更新日期:2020-10-23 00:00:00

  • Use of Rhizobacteria and Mycorrhizae Consortium in the Open Field as a Strategy for Improving Crop Nutrition, Productivity and Soil Fertility.

    abstract::Plant growth promoting rhizobacteria (PGPR) and arbuscular mycorrhizal fungi (AMF) are known for their beneficial effects. In recent years, more attention has been paid to their use as biofertilizers to reduce the use of chemical fertilizers causing significant damage to the environment. To have high plant yields, bio...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2019.01106

    authors: Raklami A,Bechtaoui N,Tahiri AI,Anli M,Meddich A,Oufdou K

    更新日期:2019-05-21 00:00:00

  • Environmental and Host Effects on Skin Bacterial Community Composition in Panamanian Frogs.

    abstract::Research on the amphibian skin microbiota has focused on identifying bacterial taxa that deter a pathogenic chytrid fungus, and on describing patterns of microbiota variation. However, it remains unclear how environmental variation affects amphibian skin bacterial communities, and whether the overall functional divers...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2018.00298

    authors: Varela BJ,Lesbarrères D,Ibáñez R,Green DM

    更新日期:2018-02-22 00:00:00

  • Metatranscriptome Analysis Deciphers Multifunctional Genes and Enzymes Linked With the Degradation of Aromatic Compounds and Pesticides in the Wheat Rhizosphere.

    abstract::Agricultural soils are becoming contaminated with synthetic chemicals like polyaromatic compounds, petroleum hydrocarbons, polychlorinated biphenyls (PCBs), phenols, herbicides, insecticides and fungicides due to excessive dependency of crop production systems on the chemical inputs. Microbial degradation of organic p...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2018.01331

    authors: Singh DP,Prabha R,Gupta VK,Verma MK

    更新日期:2018-07-03 00:00:00

  • Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry-Based Metabolomics Reveals Metabolic Alterations in the Mouse Cerebellum During Toxoplasma gondii Infection.

    abstract::Toxoplasma gondii is a protozoan parasite with a remarkable neurotropism. We recently showed that T. gondii infection can alter the global metabolism of the cerebral cortex of mice. However, the impact of T. gondii infection on the metabolism of the cerebellum remains unknown. Here we apply metabolomic profiling to di...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.01555

    authors: Ma J,He JJ,Hou JL,Zhou CX,Elsheikha HM,Zhu XQ

    更新日期:2020-07-10 00:00:00

  • NprR-NprX Quorum-Sensing System Regulates the Algicidal Activity of Bacillus sp. Strain S51107 against Bloom-Forming Cyanobacterium Microcystis aeruginosa.

    abstract::Harmful cyanobacterial blooms have severely impaired freshwater quality and threatened human health worldwide. Here, a Gram-positive bacterium, Bacillus sp. strain S51107, which exhibits strong algicidal activity against Microcystis aeruginosa, was isolated from Lake Taihu. We found that the algicidal activity of stra...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2017.01968

    authors: Wu L,Guo X,Liu X,Yang H

    更新日期:2017-10-11 00:00:00

  • Different Transcriptional Responses from Slow and Fast Growth Rate Strains of Listeria monocytogenes Adapted to Low Temperature.

    abstract::Listeria monocytogenes has become one of the principal foodborne pathogens worldwide. The capacity of this bacterium to grow at low temperatures has opened an interesting field of study in terms of the identification and classification of new strains of L. monocytogenes with different growth capacities at low temperat...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2016.00229

    authors: Cordero N,Maza F,Navea-Perez H,Aravena A,Marquez-Fontt B,Navarrete P,Figueroa G,González M,Latorre M,Reyes-Jara A

    更新日期:2016-03-01 00:00:00

  • Silencing of Anopheles stephensi Heme Peroxidase HPX15 Activates Diverse Immune Pathways to Regulate the Growth of Midgut Bacteria.

    abstract::Anopheles mosquito midgut harbors a diverse group of endogenous bacteria that grow extensively after the blood feeding and help in food digestion and nutrition in many ways. Although, the growth of endogenous bacteria is regulated by various factors, however, the robust antibacterial immune reactions are generally sup...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2016.01351

    authors: Kajla M,Choudhury TP,Kakani P,Gupta K,Dhawan R,Gupta L,Kumar S

    更新日期:2016-08-31 00:00:00

  • Genetic variability and evolutionary dynamics of viruses of the family Closteroviridae.

    abstract::RNA viruses have a great potential for genetic variation, rapid evolution and adaptation. Characterization of the genetic variation of viral populations provides relevant information on the processes involved in virus evolution and epidemiology and it is crucial for designing reliable diagnostic tools and developing e...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2013.00151

    authors: Rubio L,Guerri J,Moreno P

    更新日期:2013-06-26 00:00:00

  • Substrate Pre-loading Influences Initial Colonization of GAC Biofilter Biofilms.

    abstract::Microbial community composition and stability affect pollutant removal for biological/granular activated carbon (BAC/GAC) processes. Here, we pre-loaded the organic carbon substrates sucrose, lactose, and Lysogeny Broth (LB) medium onto new GAC prior to use and then tested whether this substrate pre-loading promoted d...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.596156

    authors: Qin W,Hammes F

    更新日期:2021-01-12 00:00:00

  • Pandemic (H1N1) 2009 Influenza Virus Infection in A Survivor Who Has Recovered from Severe H7N9 Virus Infection, China.

    abstract::We firstly report a patient who presented with severe complications after infection with influenza A(H1N1) pdm2009, more than 1 year after recovery from severe H7N9 virus infections. The population of patients who recovered from severe H7N9 infections might be at a higher risk to suffer severe complications after seas...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2016.01514

    authors: Chen SH,Wu MN,Qian YH,Ma GY,Wang GL,Yang Y,Zhao T,Lu B,Ma MJ,Cao WC

    更新日期:2016-10-04 00:00:00

  • Potential TMA-Producing Bacteria Are Ubiquitously Found in Mammalia.

    abstract::Human gut bacteria metabolize dietary components such as choline and carnitine to trimethylamine (TMA) that is subsequently oxidized to trimethylamine-N-oxide (TMAO) by hepatic enzymes. Increased plasma levels of TMAO are associated with the development of cardiovascular and renal disease. In this study, we applied ge...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2019.02966

    authors: Rath S,Rud T,Pieper DH,Vital M

    更新日期:2020-01-09 00:00:00