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Simple renal cyst and abdominal aortic aneurysm.

Abstract：

OBJECTIVE:To summarize the association of simple renal cyst (SRC) with abdominal aortic aneurysm (AAA), we reviewed currently available clinical studies with a systematic literature search and meta-analytic evaluation. METHODS:To identify all case-control studies evaluating the association of SRC with AAA, databases including MEDLINE and Embase were searched through April 2015 using web-based search engines (PubMed and Ovid). For each study, data regarding SRC prevalence in both the AAA and control groups were used to generate unadjusted odds ratios (ORs) and 95% confidence intervals. When an adjusted OR (by the use of multivariable logistic regression) was available, we preferentially abstracted the adjusted OR rather than an unadjusted OR. RESULTS:Of 139 potentially relevant articles screened initially, 5 eligible case-control studies enrolling a total of 2897 participants were identified and included. A pooled analysis of seven estimates from the five studies demonstrated a statistically significant 2.54-fold prevalence of SRC in patients with AAA relative to subjects without AAA (OR, 2.54; 95% confidence interval, 1.93-3.34; P < .00001). CONCLUSIONS:Our meta-analytic evaluation demonstrated 2.5-fold prevalence of SRC in patients with AAA relative to subjects without AAA, which suggests that SRC is associated with AAA.

journal_name

J Vasc Surg

journal_title

Journal of vascular surgery

authors

Takagi H,Umemoto T,ALICE (All-Literature Investigation of Cardiovascular Evidence) Group.

doi

10.1016/j.jvs.2015.08.095

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

254-9.e1

issue

1

eissn

0741-5214

issn

1097-6809

pii

S0741-5214(15)01845-5

journal_volume

63

pub_type

杂志文章,meta分析,评审

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