Abstract：
:Recurrent carotid stenosis occurs randomly in approximately 10% of patients undergoing endarterectomy. Previous studies have described several histologic features but have failed to clearly elucidate the pathogenesis of this disorder. To improve our understanding of this disease, we reviewed pathologic lesions from 20 patients with recurrent stenosis. All specimens had been fixed in formalin and were embedded in paraffin and had undergone routine microscopic studies. In addition, immunoperoxidase staining with anti-factor VIII for endothelial cells and anti-desmin and anti-actin for smooth muscle cells was performed. Recurrent stenosis had developed in 16 of the 20 specimens within 2 years of endarterectomy (early), whereas the remaining four cases occurred from 2 to 7 years after the original carotid endarterectomy (late). Endothelial cells were found lining the luminal surface of both early and late recurrent lesions. Six of sixteen early and three of four late specimens had areas of luminal surface covered with cells exhibiting immunoreactivity for anti-factor VIII. Cells showing immunoreactivity for actin or desmin and demonstrating the morphology of smooth muscle cells were found in 9 of 16 early restenotic lesions but in no late ones. Areas of endothelial cell lining of the recurrent carotid lesions in a substantial number of patients in this study represent a finding not previously described. The presence of these cells implies that a phase of the arterial healing after endarterectomy involves re-endothelialization. Contrary to previous reports, no significant role of thrombosis and/or intraplaque hemorrhage could be found to contribute to development of recurrent stenosis.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
J Vasc Surgjournal_title
Journal of vascular surgeryauthors
Schwarcz TH,Yates GN,Ghobrial M,Baker WHdoi
10.1067/mva.1987.avs0050280subject
Has Abstractpub_date
1987-02-01 00:00:00pages
280-8issue
2eissn
0741-5214issn
1097-6809pii
S0741521487000363journal_volume
5pub_type
杂志文章abstract：:A 53-year-old woman with Loeys-Dietz syndrome developed progressive subclavian artery aneurysm and common carotid artery dissection. She was treated successfully by plugging and coiling of the subclavian aneurysm and its side branches after combined cervical debranching using standard carotid-axillary bypass and Gore ...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2013.09.031
更新日期：2015-03-01 00:00:00
abstract：OBJECTIVES:Carotid artery stenting (CAS) has been recommended as an alternative to carotid endarterectomy (CEA) by some clinicians. However, recently published clinical trials have reported 30-day stroke and death rates of 10% to 12%. This prompted review of our experience with CAS in patients at high risk, to document...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/s0741-5214(02)75448-7
更新日期：2003-06-01 00:00:00
abstract：OBJECTIVE:Contemporary data on outcomes in open thoracoabdominal aortic aneurysm (TAAA) repair are limited to reports from major aortic referral centers showing excellent outcomes. This study aimed to characterize the national experience of open TAAA repair using national outcomes data, with a primary focus on the asso...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2020.05.027
更新日期：2021-02-01 00:00:00
abstract：:This study was performed to evaluate the results of peripheral vascular reconstruction for arterial occlusive disease in patients with juvenile-onset diabetes mellitus. The results of 67 bypass procedures performed on 60 patients with juvenile-onset diabetes mellitus between Jan. 1, 1984 and Dec. 31, 1989, were review...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：
更新日期：1992-02-01 00:00:00
abstract：PURPOSE:The purpose of this study was to determine factors that may influence patient selection for surgery in recurrent carotid stenosis (RCS) and to contrast the results of primary and secondary carotid endarterectomy (CENDX) with regard to operative morbidity and stroke prevention. METHODS:Forty-eight patients who ...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/s0741-5214(96)70095-2
更新日期：1996-08-01 00:00:00
abstract：INTRODUCTION:Arterial endarterectomy and reconstruction during carotid endarterectomy (CEA) can be performed in a variety of ways, including standard endarterectomy with primary closure, standard endarterectomy with patch angioplasty, and eversion endarterectomy. The optimal method of arterial reconstruction remains a ...
journal_title：Journal of vascular surgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jvs.2005.07.043
更新日期：2005-11-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to examine the practice patterns of intraoperative completion imaging (CI) for lower extremity bypass (LEB) in the Vascular Quality Initiative (VQI). METHODS:A retrospective review of all LEB procedures in the VQI database from January 2003 to October 2013 was performed. Regions...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2014.12.046
更新日期：2015-05-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to analyze the incidence, severity, and etiologic factors of the development of colon ischemia after endovascular aortoiliac aneurysm repair (EVAR). METHODS:During the last 9 years we performed 278 elective EVARs using a variety of grafts. To facilitate these repairs, one hypoga...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1067/mva.2001.119241
更新日期：2001-12-01 00:00:00
abstract：BACKGROUND:Complex forms of congenital venous malformation have defied proper classification and confounded therapy. Through a newly designed multidisciplinary approach, these venous defects were properly diagnosed and classified according to the Hamburg classification. Absolute ethanol was adopted as a new scleroagent...
journal_title：Journal of vascular surgery
pub_type： 评论,杂志文章
doi：10.1067/mva.2001.112209
更新日期：2001-04-01 00:00:00
abstract：:A case of popliteal entrapment syndrome is reported, in which the patient experienced symptoms of tibial nerve entrapment. Exploratory surgery revealed an abnormal fibrous band between the heads of the gastrocnemius muscle that was compressing both the tibial nerve and popliteal artery. Division of this band provided ...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：
更新日期：1985-03-01 00:00:00
abstract：:A total of 1193 patients with infrarenal abdominal aortic aneurysms were treated with the AneuRx Stent Graft System at 19 US investigational centers from 1996 to 1999. This report summarizes clinical data collected and analyzed as of August 28, 2002. There have been 10 late (>30 days) aneurysm ruptures, 8 late (>30 da...
journal_title：Journal of vascular surgery
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1067/s0741-5214(03)70038-x
更新日期：2003-04-01 00:00:00
abstract：OBJECTIVE:Guidelines from the Society for Vascular Surgery and the Choosing Wisely campaign recommend that peripheral vascular interventions (PVIs) be limited to claudication patients with lifestyle-limiting symptoms only after a failed trial of medical and exercise therapy. We sought to explore practice patterns and p...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2019.05.005
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to determine the effect of patient compliance on a program of watchful waiting in cases of small abdominal aortic aneurysms and to document the proportion of patients who become prohibitive operative risks during follow-up. STUDY DESIGN:A retrospective review was conducted at a ...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1067/mva.2000.108635
更新日期：2000-09-01 00:00:00
abstract：:A mathematic model of unilateral iliac vein obstruction was used to establish the theoretic basis for selecting saphenous vein or a larger diameter prosthetic cross-femoral venous bypass graft for relief of obstructive venous hypertension. Common femoral vein resting and postexercise peak flows, and common femoral vei...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：
更新日期：1991-05-01 00:00:00
abstract：OBJECTIVE:To define diameter at three levels along the popliteal artery and its relation to the inflow arteries in the normal state and in popliteal aneurysms. METHODS:The external diameter of the arteries was determined by duplex ultrasound scanning at the common femoral (CFA), superficial femoral artery (SFA), proxi...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2005.11.026
更新日期：2006-03-01 00:00:00
abstract：PURPOSE:We have purified and partially sequenced a protein from the adventitia of the human aorta (aortic aneurysm antigenic protein 40 kDa; AAAP-40) that has homologies to bovine aortic microfibril-associated glycoprotein (MAGP-36). It is immunoreactive with immunoglobulin G (IgGs) purified from the serum and aortic w...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/s0741-5214(97)70194-0
更新日期：1997-08-01 00:00:00
abstract：OBJECTIVES:The purpose of this study was to evaluate the relative risks and advantages of using external jugular vein (EJV) patch, compared with polytetrafluoroethylene (PTFE) patch, during carotid endarterectomy. The primary end point was the relevant neurologic complication rate (RNCR; fatal or disabling stroke) at a...
journal_title：Journal of vascular surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0741-5214(03)00912-1
更新日期：2003-12-01 00:00:00
abstract：OBJECTIVE:Aberrant subclavian artery (aSCA) is a rare anatomic variant whose association with other aortic branch variations and aortic pathology has yet to be established. Knowledge of such an association could be relevant to recommendations for screening and awareness as associated variations are important for operat...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2020.01.042
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:Promising results of thoracic endovascular aortic repair (TEVAR) in patients with complicated type B aortic dissection (TBAD) have been well documented. However, whereas early results have led many to hypothesize a benefit of TEVAR in uncomplicated patients, the natural history of TEVAR after the treatment o...
journal_title：Journal of vascular surgery
pub_type： 杂志文章,评审
doi：10.1016/j.jvs.2017.06.067
更新日期：2017-09-01 00:00:00
abstract：OBJECTIVE:In the absence of suitable autologous vein, the use of prosthetic grafts for infragenicular bypasses in peripheral arterial disease has become standard practice. The purpose of this study was to investigate whether creating a vein patch at the distal anastomosis would further improve patency and freedom from ...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2017.11.073
更新日期：2018-07-01 00:00:00
abstract：BACKGROUND:Ankle-brachial pressure index (ABI) is a simple, inexpensive, and useful tool in the detection of peripheral arterial occlusive disease (PAD). The current guidelines published by the American Heart Association define ABI as the quotient of the higher of the systolic blood pressures (SBPs) of the two ankle ar...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2006.05.016
更新日期：2006-09-01 00:00:00
abstract：OBJECTIVES:The objectives of this study were to investigate variations between states and changes in state-specific carotid endarterectomy (CEA) and 30-day mortality rates. Cross-sectional variations and changes over time in such measures may be indicative of improvement in the quality of care. METHODS:We performed re...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/s0741-5214(03)00616-5
更新日期：2003-10-01 00:00:00
abstract：OBJECTIVE:The two techniques for carotid endarterectomy (CEA)--conventional (C-CEA) and eversion (E-CEA)--have different effects on blood pressure. This study compared sympathetic activity after C-CEA and E-CEA, as measured by renin and catecholamine levels. METHODS:E-CEA (n = 40) and C-CEA (n = 34) were performed in ...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2012.01.051
更新日期：2012-08-01 00:00:00
abstract：PURPOSE:Although many studies have well established that carotid endarterectomy (CEA) is beneficial in selected patients with severe carotid disease, only a few large studies have focused on the durability of the surgical procedure. Carotid artery angioplasty and stenting (CAS) has recently been proposed as a potential...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2004.04.005
更新日期：2004-08-01 00:00:00
abstract：OBJECTIVE:Computed tomographic angiography (CTA) is currently the most commonly used technique for postoperative surveillance to detect endoleaks after endovascular stent graft repair of abdominal aortic aneurysms. We have evaluated the efficacy of duplex ultrasound scan with the addition of an ultrasound scan contrast...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1067/mva.2003.17
更新日期：2003-02-01 00:00:00
abstract：BACKGROUND:The initial treatment of patients with acute limb ischemia (ALI) remains undefined. The aim of this article was to compare the safety and effectiveness of catheter-driven thrombolysis (CDT) with surgical revascularization and evaluate the various fibrinolytic agents, endovascular, and pharmacochemical approa...
journal_title：Journal of vascular surgery
pub_type： 杂志文章,meta分析
doi：10.1016/j.jvs.2019.05.031
更新日期：2020-02-01 00:00:00
abstract：BACKGROUND:An arteriovenous loop (AVL) enclosed in a polycarbonate chamber in vivo, produces a fibrin exudate which acts as a provisional matrix for the development of a tissue engineered microcirculatory network. OBJECTIVES:By administering enoxaparin sodium - an inhibitor of fibrin polymerization, the significance o...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2008.05.021
更新日期：2008-10-01 00:00:00
abstract：INTRODUCTION:Acute aortic dissection (AAD) is one of the most common aortic emergencies that vascular specialists are asked to manage. Traditional surgical interventions for cases complicated by malperfusion have resulted in significant morbidity and mortality. With increasing availability of thoracic endografts, endov...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2011.04.025
更新日期：2011-11-01 00:00:00
abstract：:Lesions of the internal carotid artery involving the bifurcation and the intrapetrous portion represent a challenging therapeutic situation. We herein report the first case of a patient suffering from tinnitus which was treated by simultaneous carotid endarterectomy of the bifurcation and transluminal angioplasty and ...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2003.10.034
更新日期：2004-03-01 00:00:00
abstract：PURPOSE:This study was done to evaluate the use of published standardized risk factors for venous thromboembolism (VTE) in patients admitted to a trauma intensive care unit (ICU) and to derive guidelines for the use of low molecular weight heparin (LMWH) and surveillance venous Doppler ultrasound scanning (VDUS). METH...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/s0741-5214(98)70161-2
更新日期：1998-08-01 00:00:00
