Evaluating the Impact and Cost-Effectiveness of Statin Use Guidelines for Primary Prevention of Coronary Heart Disease and Stroke.

abstract：:To describe the coronary arteriographic findings during early transmural myocardial infarction and to define the prevalence of coronary thrombosis by arteriography, we performed coronary arteriography and left ventriculography within 24 hours from symptom onset of transmural myocardial infarction in 517 patients. The ...

journal_title：Circulation

authors： DeWood MA,Spores J,Hensley GR,Simpson CS,Eugster GS,Sutherland KI,Grunwald RP,Shields JP

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:A growing body of evidence from animal studies supports the hypothesis that oxidative stress-mediated mechanisms play a central role in early atherogenesis. In contrast, clinical trials with antioxidant vitamins have not produced consistent results in humans with established atherosclerosis. METHODS AND RES...

journal_title：Circulation

authors： Cyrus T,Yao Y,Rokach J,Tang LX,Praticò D

更新日期：2003-02-04 00:00:00

abstract：BACKGROUND:Little information is available regarding the occurrence of perioperative and late cardiac events in women with vascular disease. The current study was performed to examine whether sex-specific differences exist in these outcomes in a large population of vascular surgery patients and to determine the value o...

journal_title：Circulation

authors： Hendel RC,Chen MH,L'Italien GJ,Newell JB,Paul SD,Eagle KA,Leppo JA

更新日期：1995-02-15 00:00:00

abstract：BACKGROUND:To assess the extent and nature of the dysfunction surrounding aneurysms of the left ventricle (LV), we examined the parameters of local and global three-dimensional shape, size, and function of LVs of eight patients with histologically confirmed anterior fibrous aneurysms. METHODS AND RESULTS:Three-dimensi...

journal_title：Circulation

authors： Lessick J,Sideman S,Azhari H,Marcus M,Grenadier E,Beyar R

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Adriamycin (ADR) is an anticancer drug known to cause severe cardiac toxicity by generating free radicals. We investigated the role of a redox-regulating molecule, thioredoxin-1 (TRX1), in ADR-induced cardiotoxicity. METHODS AND RESULTS:The in vitro study showed that TRX1 was dose-dependently increased conc...

journal_title：Circulation

authors： Shioji K,Kishimoto C,Nakamura H,Masutani H,Yuan Z,Oka S,Yodoi J

更新日期：2002-09-10 00:00:00

abstract：BACKGROUND:Theoretically, the efficacy of continuous warm blood cardioplegia may be improved when administered retrogradely (RCWBC) rather than antegradely (ACWBC) in the setting of acute regional ischemia because of enhanced oxygen and substrate delivery to myocardial tissue distal to an acute coronary artery occlusio...

journal_title：Circulation

authors： Misare BD,Krukenkamp IB,Lazer ZP,Levitsky S

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Less invasive methods are replacing traditional invasive means of measuring coronary flow reserve (CFR). Transesophageal echocardiography (TEE) is becoming a useful tool for evaluation of coronary artery disease and has recently been used to measure CFR. This has always been done using dipyridamole, but aden...

journal_title：Circulation

authors： Redberg RF,Sobol Y,Chou TM,Malloy M,Kumar S,Botvinick E,Kane J

更新日期：1995-07-15 00:00:00

abstract：BACKGROUND:Aging results in vascular stiffening and an increase in the velocity of the pressure wave as it travels down the aorta. Increased aortic pulse wave velocity (aPWV) has been associated with mortality in clinical but not general populations. The objective of this investigation was to determine whether aPWV is ...

journal_title：Circulation

authors： Sutton-Tyrrell K,Najjar SS,Boudreau RM,Venkitachalam L,Kupelian V,Simonsick EM,Havlik R,Lakatta EG,Spurgeon H,Kritchevsky S,Pahor M,Bauer D,Newman A,Health ABC Study.

更新日期：2005-06-28 00:00:00

abstract：BACKGROUND:The future risk of myocardial infarction is commonly assessed using cardiovascular risk scores, coronary artery calcium score, or coronary artery stenosis severity. We assessed whether noncalcified low-attenuation plaque burden on coronary CT angiography (CCTA) might be a better predictor of the future risk ...

journal_title：Circulation

authors： Williams MC,Kwiecinski J,Doris M,McElhinney P,D'Souza MS,Cadet S,Adamson PD,Moss AJ,Alam S,Hunter A,Shah ASV,Mills NL,Pawade T,Wang C,Weir McCall J,Bonnici-Mallia M,Murrills C,Roditi G,van Beek EJR,Shaw LJ,Nicol E

更新日期：2020-05-05 00:00:00

abstract：:The effect of cycle length on atrial vulnerability was studied in 14 patients manifesting reproducible repetitive atrial firing during atrial extra-stimulus (A2) testing. Repetitive atrial firing was defined as the occurrence of two or more premature atrial responses with return cycle (A2-A3) of 250 msec or less and s...

journal_title：Circulation

authors： Wyndham CR,Amat-y-Leon F,Wu D,Denes P,Dhingra R,Simpson R,Rosen KM

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:At physiological concentrations, 17beta-estradiol selectively enhances endothelium-dependent coronary vasodilation by an unknown mechanism in postmenopausal women. METHODS AND RESULTS:To assess the contribution of nitric oxide (NO) to the vascular effects of estradiol, we measured coronary epicardial and mi...

journal_title：Circulation

authors： Guetta V,Quyyumi AA,Prasad A,Panza JA,Waclawiw M,Cannon RO 3rd

更新日期：1997-11-04 00:00:00

abstract：BACKGROUND:We tested the hypothesis that combined cyclooxygenase-1 (COX-1) and prostacyclin synthase (PGIS) gene transfer selectively augments prostacyclin production without a concurrent overproduction of other prostanoids. METHODS AND RESULTS:ECV304 cells were transfected with bicistronic pCOX-1/PGIS versus pCOX-1 o...

journal_title：Circulation

authors： Shyue SK,Tsai MJ,Liou JY,Willerson JT,Wu KK

更新日期：2001-04-24 00:00:00

abstract：BACKGROUND:Alpha-linolenic acid may protect against cardiovascular disease. We examined the association between adipose tissue alpha-linolenic acid and nonfatal acute myocardial infarction (MI) in a population-based case-control study in Costa Rica. METHODS AND RESULTS:The 482 case patients with a first nonfatal acute...

journal_title：Circulation

authors： Baylin A,Kabagambe EK,Ascherio A,Spiegelman D,Campos H

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:The relationship between intake of fruits and vegetables (F/V) during young adulthood and coronary atherosclerosis later in life is unclear. METHODS AND RESULTS:We studied participants of the Coronary Artery Risk Development in Young Adults (CARDIA) study, a cohort of young, healthy black and white individu...

journal_title：Circulation

authors： Miedema MD,Petrone A,Shikany JM,Greenland P,Lewis CE,Pletcher MJ,Gaziano JM,Djousse L

更新日期：2015-11-24 00:00:00

abstract：BACKGROUND:Hemodialysis vascular access dysfunction is the single most important cause of morbidity in kidney hemodialysis patients. Failure of an arteriovenous polytetrafluoroethylene (PTFE) graft, the most common form of hemodialysis access, is primarily due to intimal hyperplasia and thrombosis at the venous anastom...

journal_title：Circulation

authors： Luo Z,Akita GY,Date T,Treleaven C,Vincent KA,Woodcock D,Cheng SH,Gregory RJ,Jiang C

更新日期：2005-04-05 00:00:00

abstract：BACKGROUND:Paroxysmal atrial fibrillation (PAF) can be eliminated with continuous circular lesions (CCLs) around the pulmonary veins (PVs), but it is unclear whether all PVs are completely isolated. METHODS AND RESULTS:Forty-one patients with symptomatic PAF underwent 3D mapping, and all PV ostia were marked on the 3D...

journal_title：Circulation

authors： Ouyang F,Bänsch D,Ernst S,Schaumann A,Hachiya H,Chen M,Chun J,Falk P,Khanedani A,Antz M,Kuck KH

更新日期：2004-10-12 00:00:00

abstract：BACKGROUND:A warm-water bath (WWB) or sauna bath (SB) has generally been considered inappropriate for patients with severe congestive heart failure (CHF). However, a comprehensive investigation of the hemodynamic effects of thermal vasodilation in CHF has not been previously undertaken. METHODS AND RESULTS:To investig...

journal_title：Circulation

authors： Tei C,Horikiri Y,Park JC,Jeong JW,Chang KS,Toyama Y,Tanaka N

更新日期：1995-05-15 00:00:00

abstract：BACKGROUND:This study sought to evaluate the clinical impact of angiographic complete revascularization (CR) after drug-eluting stent implantation or coronary artery bypass graft surgery for multivessel coronary disease. METHODS AND RESULTS:A total of 1914 consecutive patients with multivessel coronary disease undergo...

journal_title：Circulation

authors： Kim YH,Park DW,Lee JY,Kim WJ,Yun SC,Ahn JM,Song HG,Oh JH,Park JS,Kang SJ,Lee SW,Lee CW,Park SW,Park SJ

更新日期：2011-05-31 00:00:00

abstract：BACKGROUND:Myocardium irreversibly injured by ischemic stress must be efficiently repaired to maintain tissue integrity and contractile performance. Macrophages play critical roles in this process. These cells transform across a spectrum of phenotypes to accomplish diverse functions ranging from mediating the initial i...

journal_title：Circulation

authors： Cao DJ,Schiattarella GG,Villalobos E,Jiang N,May HI,Li T,Chen ZJ,Gillette TG,Hill JA

更新日期：2018-06-12 00:00:00

abstract：BACKGROUND:C-reactive protein (CRP) has been proposed as an independent risk factor for cardiovascular disease and has been positively associated with body weight and body fatness. We examined the hypothesis that weight loss would reduce plasma CRP levels in obese postmenopausal women. METHODS AND RESULTS:In a sample ...

journal_title：Circulation

authors： Tchernof A,Nolan A,Sites CK,Ades PA,Poehlman ET

更新日期：2002-02-05 00:00:00

abstract：BACKGROUND:Chronic orthostatic intolerance (COI) is a debilitating autonomic condition in young adults. Its neurohumoral and hemodynamic profiles suggest possible alterations of postural sympathetic function and of baroreflex control of heart rate (HR). METHODS AND RESULTS:In 16 COI patients and 16 healthy volunteers,...

journal_title：Circulation

authors： Furlan R,Jacob G,Snell M,Robertson D,Porta A,Harris P,Mosqueda-Garcia R

更新日期：1998-11-17 00:00:00

abstract：BACKGROUND:Timely primary percutaneous coronary intervention (PPCI) cannot be offered to all patients with ST-segment-elevation myocardial infarction (STEMI). Pharmaco-invasive (PhI) strategy has been proposed as a valuable alternative for eligible patients with STEMI. We conducted a randomized study to compare the eff...

journal_title：Circulation

authors： Pu J,Ding S,Ge H,Han Y,Guo J,Lin R,Su X,Zhang H,Chen L,He B,EARLY-MYO Investigators.

更新日期：2017-10-17 00:00:00

abstract：:To study the variability of the fraction of CPK released from the infarcted heart which enters the serum (serum entry ratio, or SER) with size and model of infarction, nine dogs underwent homogeneous infarctions (LAD ligation) of varying sizes, and 10 dogs underwent scattered infarctions (left coronary embolization). ...

journal_title：Circulation

authors： Cairns JA,Missirlis E,Fallen EL

更新日期：1978-12-01 00:00:00

abstract：BACKGROUND:The endothelium acts as the sensor of shear stress and as the mediator of flow-induced changes in vessel tone and structure. The purpose of this study was to delineate the signal transduction pathway of flow-induced release of endothelium-derived relaxing factor (EDRF). METHODS AND RESULTS:We used a shear s...

journal_title：Circulation

authors： Ohno M,Gibbons GH,Dzau VJ,Cooke JP

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Postmortem interrogations of cardiac implantable electronic devices (CIEDs), recommended at autopsy in suspected cases of sudden cardiac death, are rarely performed, and data on systematic postmortem CIED analysis in the forensic pathology are missing. The aim of the study was to determine whether nonselecti...

journal_title：Circulation

authors： Lacour P,Buschmann C,Storm C,Nee J,Parwani AS,Huemer M,Attanasio P,Boldt LH,Rauch G,Kucher A,Pieske B,Haverkamp W,Blaschke F

更新日期：2018-06-19 00:00:00

abstract：:Fifty-six patients undergoing orthotopic cardiac transplantation were given Minnesota ALG prophylactically or therapeutically for acute cardiac rejection. During a follow-up period of 0-28 months (mean follow-up period, 11.9 months), the actuarial survival for the entire group was 96% and 86% at 30 days and 1 year, re...

journal_title：Circulation

authors： Keith FM,Magilligan DJ Jr,Lakier JB,Drost CJ

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Aortic counterpulsation has been observed to reduce the rate of reocclusion of the infarct-related artery after patency has been restored during acute myocardial infarction in observational studies. To evaluate the benefit-to-risk ratio of aortic counterpulsation during the early phase of myocardial infarcti...

journal_title：Circulation

authors： Ohman EM,George BS,White CJ,Kern MJ,Gurbel PA,Freedman RJ,Lundergan C,Hartmann JR,Talley JD,Frey MJ

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Plaque rupture with subsequent thrombosis is recognized as the underlying pathophysiology of most acute coronary syndromes and stroke. Thus, direct thrombus visualization may be beneficial for both diagnosis and guidance of therapy. We sought to test the feasibility of direct imaging of acute and subacute th...

journal_title：Circulation

authors： Botnar RM,Perez AS,Witte S,Wiethoff AJ,Laredo J,Hamilton J,Quist W,Parsons EC Jr,Vaidya A,Kolodziej A,Barrett JA,Graham PB,Weisskoff RM,Manning WJ,Johnstone MT

更新日期：2004-04-27 00:00:00

abstract：:More accurate characterization of coronary artery lesions is needed for evaluation of short and long-term interventions in coronary disease. A method of segmental artery analysis has been developed to maximize the information obtained from coronary arteriograms. Coronary lesions are traced from two projected, perpendi...

journal_title：Circulation

authors： Brown BG,Bolson E,Frimer M,Dodge HT

更新日期：1977-02-01 00:00:00

abstract：:Electrophysiologic studies were performed in 28 patients with documented atrioventricular (AV) nodal reentrant supraventricular tachycardia (SVT) to investigate the presence of AV nodal tissue situated between the tachycardia circuit and both the atrium (upper common pathway, UCP) and the His bundle (lower common path...

journal_title：Circulation

authors： Miller JM,Rosenthal ME,Vassallo JA,Josephson ME

更新日期：1987-05-01 00:00:00