Abstract:
:Few oral antibiotics exist for the empirical treatment of extended-spectrum β-lactamase (ESBL) urinary tract infections (UTI). In this study, we sought to determine the activity of fosfomycin against ESBL-producing uropathogens from patients at 3 Veterans Affairs (VA) facilities between 2010 and 2013. Among the ESBL uropathogens, 19.9% were fosfomycin resistant. Klebsiella species were more likely than Escherichia coli to be resistant (46% versus 4%; P < 0.001). Fosfomycin remains active against a majority of the ESBL uropathogens, although resistance among Klebsiella spp. was higher than that in previous reports.
journal_name
Antimicrob Agents Chemotherjournal_title
Antimicrobial agents and chemotherapyauthors
Linsenmeyer K,Strymish J,Weir S,Berg G,Brecher S,Gupta Kdoi
10.1128/AAC.02614-15subject
Has Abstractpub_date
2015-11-23 00:00:00pages
1134-6issue
2eissn
0066-4804issn
1098-6596pii
AAC.02614-15journal_volume
60pub_type
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