Abstract:
BACKGROUND:High morbidity has been reported with iliac crest bone graft harvesting; however, donor bone is typically necessary for posterior spinal fusion. Autograft bone combined with allograft may reduce the morbidity associated with iliac crest bone harvesting and improve the fusion rate. Our aim in this study was to determine the presence of complications, pseudarthrosis, non-union, and infection using combined in situ local autograft bone and freeze-dried cancellous allograft bone in patients undergoing posterior spinal fusion for the treatment of adolescent idiopathic scoliosis. METHODS:A combination of in situ local autograft bone and freeze-dried cancellous allograft blocks were used in 50 consecutive patients with adolescent idiopathic scoliosis treated by posterior fusion and Moss Miami pedicle screw instrumentation. Results were assessed clinically and radiographically and quality of life and functional outcome was evaluated by administration of a Chinese version of the SRS-22 survey. RESULTS:There were 41 female and 9 male patients included for analysis with an average age of 14.7 years (range, 12-17). All patients had a minimum follow-up of 18 months (range, 18 to 40 months). The average preoperative Cobb angle was 49.8 degrees (range, 40 degrees to 86 degrees ). The average number of levels fused was 9.8 (range, 6-15). Patients had a minimum postoperative follow-up of 18 months. At final follow-up, the average Cobb angle correction was 77.8% (range, 43.4 to 92.5%). There was no obvious loss in the correction, and the average loss of correction was 1.1 degrees (range, 0 degrees to 4 degrees ). There was no pseudarthrosis and no major complications. CONCLUSIONS:In situ autograft bone combined with allograft bone may be a promising method enhances spinal fusion in AIS treated with pedicle screw placement. By eliminating the need for iliac crest bone harvesting, significant morbidity may be avoided.
journal_name
BMC Musculoskelet Disordjournal_title
BMC musculoskeletal disordersauthors
Yang X,Xu H,Li M,Gu S,Fang X,Wang J,Ni J,Wu Ddoi
10.1186/1471-2474-11-159subject
Has Abstractpub_date
2010-07-14 00:00:00pages
159issn
1471-2474pii
1471-2474-11-159journal_volume
11pub_type
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