Abstract:
BACKGROUND:"Advanced Core Decompression" (ACD) is a new technique for treatment of osteonecrosis of the femoral head (ONFH) that includes removal of the necrotic tissue using a percutaneous expandable reamer followed by refilling of the drill hole and the defect with an injectable, hard-setting, composite calcium sulphate (CaSO4)-calcium phosphate (CaPO4) bone graft substitute. As autologous bone has been shown to be superior to all other types of bone grafts, the aim of the study is to present and evaluate a modified technique of ACD with impaction of autologous bone derived from the femoral neck into the necrotic defect. METHODS:A cohort of patients with an average follow-up of 30.06 months (minimum 12 months) was evaluated for potential collapse of the femoral head and any reasons that led to replacement of the operated hip. Only patients in stages 2a to 2c according to the Steinberg classification were included in the study. RESULTS:In 75.9% the treatment was successful with no collapse of the femoral head or conversion to a total hip replacement. Analysis of the results of the different subgroups showed that the success rate was 100% for stage 2a lesions and 84.6% respectively 61.5% for stages 2b and 2c lesions. CONCLUSIONS:Previous studies with a comparable follow-up reported less favourable results for ACD without autologous bone. Especially in stages 2b and 2c the additional use of autologous bone has a positive effect. In comparison to other hip-preserving techniques, the modified ACD technique is a very promising and minimally invasive method for treatment of ONFH. TRIAL REGISTRATION:German clinical trials register ( DRKS00011269 , retrospectively registered).
journal_name
BMC Musculoskelet Disordjournal_title
BMC musculoskeletal disordersauthors
Landgraeber S,Warwas S,Claßen T,Jäger Mdoi
10.1186/s12891-017-1811-ysubject
Has Abstractpub_date
2017-11-21 00:00:00pages
479issue
1issn
1471-2474pii
10.1186/s12891-017-1811-yjournal_volume
18pub_type
临床试验,杂志文章abstract:BACKGROUND:The to date evidence for a dose-response relationship between physical workload and the development of lumbar disc diseases is limited. We therefore investigated the possible etiologic relevance of cumulative occupational lumbar load to lumbar disc diseases in a multi-center case-control study. METHODS:In f...
journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章,多中心研究
doi:10.1186/1471-2474-10-48
更新日期:2009-05-07 00:00:00
abstract:BACKGROUND:Intra-articular tranexamic acid (TXA) as an adjunct to intravenous TXA was reported to decrease perioperative blood loss during unilateral total knee arthroplasty (TKA). However, there have been no randomized controlled trials comparing intravenous versus combined intravenous and intra-articular TXA administ...
journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12891-019-2890-8
更新日期:2019-10-22 00:00:00
abstract:BACKGROUND:The objective of the present study was to assess interobserver reproducibility (in terms of reliability and agreement) of active and passive measurements of knee RoM using a long arm goniometer, performed by trained physical therapists in a clinical setting in total knee arthroplasty patients, within the fir...
journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章
doi:10.1186/1471-2474-8-83
更新日期:2007-08-17 00:00:00
abstract:BACKGROUND:The main aim of the study was to investigate the relationship between persistent disease activity and radiographic progression of joint damage in early rheumatoid arthritis (ERA). METHODS:Forty-eight patients with active ERA was assessed every 3 months for disease activity for 3 years. Radiographic damage w...
journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章
doi:10.1186/1471-2474-12-120
更新日期:2011-05-30 00:00:00
abstract:BACKGROUND:Neck-shoulder pain conditions, e.g., chronic trapezius myalgia, have been associated with sensory disturbances such as increased sensitivity to experimentally induced pain. This study investigated pain sensitivity in terms of bilateral pressure pain thresholds over the trapezius and tibialis anterior muscles...
journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章
doi:10.1186/1471-2474-12-230
更新日期:2011-10-12 00:00:00
abstract:BACKGROUND:The objective of this epidemiological study is to map the dentofacial anomalies that can be correlated to the two most frequent spinal diseases responsible for postural abnormalities and that can be clinically identified by the orthodontic examination. METHODS:Twenty-three children with Scheuermann's diseas...
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pub_type: 杂志文章
doi:10.1186/1471-2474-9-169
更新日期:2008-12-22 00:00:00
abstract:BACKGROUND:A body of evidence demonstrating changes to the glutaminergic system in tendinopathy has recently emerged. This hypothesis was further tested by studying the effects of glutamate on the tenocyte phenotype, and the impact of loading and exposure to glucocorticoids on the glutamate signaling machinery. METHOD...
journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章
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更新日期:2017-05-25 00:00:00
abstract:BACKGROUND:Trunk bridging exercises are often used as therapeutic exercises for lumbopelvic stabilization. These exercises focus on the retraining of muscle coordination patterns in which optimal ratios between local segmental stabilizing and global torque producing muscle activity are assumed to be essential. However,...
journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章
doi:10.1186/1471-2474-7-75
更新日期:2006-09-20 00:00:00
abstract:BACKGROUND:About 10% of patients not responding to 3-6 months of conservative management for insertional Achilles tendinopathy undergo surgery. Traditionally, surgery of the Achilles tendon is performed through longitudinal extensile incisions. Such surgery is prone to the complications of wound healing, wound breakdow...
journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章
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更新日期:2007-08-15 00:00:00
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journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章
doi:10.1186/1471-2474-14-144
更新日期:2013-04-23 00:00:00
abstract:BACKGROUND:Our study aim was to compare allogeneic cancellous bone (ACB) and synthetic or highly-processed xenogeneic bone substitutes (SBS) in the treatment of skeletal defects in orthopedic surgery. METHODS:232 patients treated for bony lesions with ACB (n = 116) or SBS (n = 116) within a 10-year time period were in...
journal_title:BMC musculoskeletal disorders
pub_type: 临床试验,杂志文章
doi:10.1186/s12891-016-0930-1
更新日期:2016-02-13 00:00:00
abstract:BACKGROUND:Chronic diseases and multimorbidity are increasingly common among persons in working age. This study explores the impact of type, number and combinations of chronic diseases with focus on the role of MSKD on (1) adverse work status (i.e. work disability (WD), economic unemployment (UE) or receiving a living ...
journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章
doi:10.1186/s12891-016-1365-4
更新日期:2017-01-10 00:00:00
abstract:BACKGROUND:Total knee arthroplasty (TKA) is the most frequently performed joint replacement surgery in North America. Patient perspectives on TKA have been investigated in various ways, including finding as many as 20% of TKA patients are dissatisfied with their surgical outcomes. Understanding the patient experience w...
journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章
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更新日期:2017-03-24 00:00:00
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journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章
doi:10.1186/1471-2474-3-22
更新日期:2002-10-03 00:00:00
abstract:BACKGROUND:Systemic sclerosis (SSc) is a rheumatologic disease with a multifactorial etiology. Genome-wide association studies imply a polygenic, complex mode of inheritance with contributions from variation at the human leukocyte antigen locus and non-coding variation at a locus on chromosome 6p21, among other modestl...
journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章
doi:10.1186/s12891-016-1320-4
更新日期:2016-11-09 00:00:00
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journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章
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更新日期:2011-04-06 00:00:00
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journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章
doi:10.1186/s12891-017-1512-6
更新日期:2017-04-20 00:00:00
abstract:BACKGROUND:There is a wide range of mechanical properties of spinal ligaments documented in literature. Due to the fact that ligaments contribute in stabilizing the spine by limiting excessive intersegmental motion, those properties are of particular interest for the implementation in musculoskeletal models. The aim of...
journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章
doi:10.1186/s12891-016-0942-x
更新日期:2016-02-22 00:00:00
abstract:BACKGROUND:Conversion of a knee arthrodesis to a Total Knee Arthroplasty is an uncommon procedure. Revision Total Knee Arthroplasty in this setting presents the surgeon with a number of challenges including the management of the extensor mechanism and patella. CASE PRESENTATION:We describe a unique case of a 69 years ...
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abstract:BACKGROUND:This double-blind, randomized, controlled trial investigated the effect of the phosphodiesterase-5 inhibitor tadalafil on the microcirculation in patients with cold Complex Regional Pain Syndrome (CRPS) in one lower extremity. METHODS:Twenty-four patients received 20 mg tadalafil or placebo daily for 12 wee...
journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章,随机对照试验
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journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章,多中心研究
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pub_type: 杂志文章
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更新日期:2020-11-14 00:00:00
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journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章
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journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章
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更新日期:2004-08-26 00:00:00
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journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章
doi:10.1186/1471-2474-13-228
更新日期:2012-11-22 00:00:00
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journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章
doi:10.1186/1471-2474-13-50
更新日期:2012-04-02 00:00:00
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journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章
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journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章
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更新日期:2019-11-09 00:00:00
abstract:BACKGROUND:In end-stage knee osteoarthritis total knee arthroplasty (TKA) is an effective intervention to reduce pain and improve functioning in the majority of patients. However, after TKA some patients still experience pain, loss of function, deficient muscle strength or reduced walking speed. This study systematical...
journal_title:BMC musculoskeletal disorders
pub_type: 杂志文章
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更新日期:2018-07-25 00:00:00
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pub_type: 杂志文章
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更新日期:2015-03-29 00:00:00