[Effect of acute alcohol intake on certain cardiovascular functions in healthy young males].

Abstract:

:.15, 0.25 and 0.5 g/kg alcohol in the form of 40% brandy in one week intervals was consumed by eight healthy, regularly trained young men volunteers. Blood alcohol level, blood pressure and ECG were registered before and 30, 60 and 90 min after, each alcohol consumption. The cardiac output was measured with a radiocirculographic method before and 45 min after alcohol consumption. The cardiac index, stroke volume, stroke index, and total peripheral resistance (TPR) were calculated. With increase of the alcohol dose the blood alcohol level increased, while cardiac output, cardiac index, stroke volume, stroke index, and the systolic blood pressure fell. The other parameters examined--heart rate, diastolic blood pressure, TPR among others--remained unchanged. The ECG was normal. The highest no effect alcohol dose was less than 0.15 g/kg (0.1, k/kg). It is concluded that, depending on the dose, alcohol has practically no effect on the majority of the heart-functions, however, in the range of 0.1 to 0.5 g/kg it has a depressive influence, i.e. lowers the pump-function of the heart and, at 0.5 g/kg the arterial blood pressure.

journal_name

Orv Hetil

journal_title

Orvosi hetilap

authors

Movai V,Nádházi Z,Molnár G,Ungváry G,Folly G

subject

Has Abstract

pub_date

1989-12-24 00:00:00

pages

2785-9

issue

52

eissn

0030-6002

issn

1788-6120

journal_volume

130

pub_type

临床试验,杂志文章,评审
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