Abstract:
OBJECTIVES:Clostridium difficile infection (CDI) is the most common healthcare-associated infection in the United States. Clinical practice guidelines for the treatment of CDI were updated in 2010 by the Society for Healthcare Epidemiology of America and the Infectious Diseases Society of America. An institutional guideline for the classification and management of CDI in accordance with the 2010 Society for Healthcare Epidemiology of America/Infectious Diseases Society of America guideline was developed and provided to attending physicians and medical residents in multiple formats. METHODS:We sought to determine the impact of an evidence-based guideline for the treatment of CDI at a community teaching hospital. A retrospective chart review was conducted to identify length of stay (LOS), readmission rates, direct cost, mortality, and physician adherence to guidelines in patients with International Classification of Diseases, Ninth Edition codes and laboratory confirmation of CDI between February 1, 2013 and January 31, 2014. Endpoints included LOS after diagnosis of CDI, 30-day readmission rates, direct cost after diagnosis of CDI, and mortality. RESULTS:A total of 351 patient encounters were included in the study. Although not statistically significant, it was found that guideline-based therapy (n = 131) was associated with a lower median LOS (6 days vs 8 days; P = 0.06). Thirty-day hospital readmission (25.2% vs 29.5%; P = 0.39) and median cost after diagnosis of CDI ($7238.48 vs $8794.81; P = 0.10) also were lower but not statistically significant. Patients with mild-to-moderate infection were found to have a significantly lower median LOS (5 days vs 7 days; P = 0.03) and median cost after diagnosis ($5257.85 vs $7680.56; P = 0.03) when treated with guideline-based therapy. Overall physician adherence to guidelines was low, at 38%. CONCLUSIONS:Treatment with guideline-based therapy for CDI was associated with a trend toward a significantly lower LOS and cost. Barriers to physician adherence to guidelines still exist, despite education and guideline availability. Electronic health record-based order sets or clinical decision tools may improve recognition of and adherence to guidelines.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Knaus SJ,Saum L,Cochard E,Prichard W,Skinner B,Medas Rdoi
10.14423/SMJ.0000000000000428subject
Has Abstractpub_date
2016-03-01 00:00:00pages
144-50issue
3eissn
0038-4348issn
1541-8243pii
SMJ50161journal_volume
109pub_type
杂志文章abstract::Coronary heart disease (CHD) is the leading cause of morbidity and mortality in patients more than 65 years old. Within this population, elevated cholesterol levels are prevalent and associated with increased risk of CHD. Despite increasing emphasis on lipid-lowering treatment in the elderly population, questions rema...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2002-11-01 00:00:00
abstract::Phenformin-associated lactic acidosis is an important though unusual cause of acute abdominal pain. Its clinical picture suggests other catastrophic abdominal entities. A representative case is presented. Aids to arriving at this diagnosis are presented and the specific therapy is outlined. The pathophysiology of this...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197803000-00039
更新日期:1978-03-01 00:00:00
abstract:OBJECTIVES:Insurance status has the potential to play a significant role in an individual's health care by affecting the time of diagnosis and the treatment options used. Our study reviewed insurance status as a determinant of the time of a breast cancer diagnosis as well as the surgical treatment options offered. MET...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000281
更新日期:2015-05-01 00:00:00
abstract::We have described a 38-year-old woman with a lesion of the cervix found on routine physical examination. The lesion proved to be a primary leiomyosarcoma of the cervix. Despite radiation therapy, surgery, and chemotherapy, the tumor recurred and grew relentlessly. She is alive with disease at two years seven months af...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198104000-00042
更新日期:1981-04-01 00:00:00
abstract::This is a prospective clinical study of 41 consecutive patients with isolated tears of the medial meniscus who underwent meniscectomy by conventional arthrotomy. The results are presented in terms of length of hospitalization, complications, analgesic requirements during hospitalization, and ability to regain muscle c...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198309000-00021
更新日期:1983-09-01 00:00:00
abstract::Two cases are reviewed which presented findings strongly suggesting congenital synostosis between the third metatarsal and third cuneiform bones. Supplementary x-ray films proved these joints to be present and intact. This point, though well known to skeletal radiologists, is worthy of emphasis to nonskeletal radiolog...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract:OBJECTIVES:Hematological malignancies of the breast share a presentation similar to primary breast carcinomas but differ substantially in therapeutic approach and clinical outcomes. In this study, we investigate the frequency of hematological malignancies, their relative primary and secondary occurrences, and further c...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000710
更新日期:2017-10-01 00:00:00
abstract::Buried bumper syndrome (BBS) is an uncommon complication of percutaneous endoscopic gastrostomy (PEG) tube placement. This unusual phenomenon occurs when the internal bumper of a PEG tube erodes and migrates through the gastric wall and becomes lodged anywhere between the gastric wall and the skin. If not removed and ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181fa73d0
更新日期:2010-12-01 00:00:00
abstract::We have presented a case of chronic pancreatitis with pseudocyst involvement of the spleen complicated by splenic rupture. This complication is uncommon, only 19 cases having been reported. As illustrated by our case, there is a high risk of hemorrhage from a pseudocyst involving the spleen and pancreas. Immediate sur...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198807000-00025
更新日期:1988-07-01 00:00:00
abstract::A 66-year-old white male presented with jaundice, pruritus, and a 30-pound weight loss over two months. Physical examination revealed scleral icterus. Laboratory evaluation revealed ALT 161 U/L, AST 290 U/L, alkaline phosphatase 2004 U/L, GGT 2,552 U/L, total bilirubin 10.2 mg/dL, and a carbohydrate antigen 19-9 (CA 1...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000202695.97123.2b
更新日期:2006-03-01 00:00:00
abstract::We have described three cases of adenomyoma of the stomach. These benign lesions are found almost exclusively in the antrum or pylorus and are composed of combinations of ducts, glands, pancreatic tissue, and smooth muscle. Malignancy arising in adenomyomas is rare. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198410000-00037
更新日期:1984-10-01 00:00:00
abstract:BACKGROUND:Between 1995 and 1997, a tuberculosis outbreak occurred in a large, urban jail. We investigated whether the outbreak strain of Mycobacterium tuberculosis (M. tuberculosis) was circulating in the surrounding community after that outbreak. METHODS:We performed a retrospective cohort study of people with tuber...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000053678.62096.6F
更新日期:2003-02-01 00:00:00
abstract::Digital subtraction angiography (DSA) provides additional information regarding patency or occlusion of vessels that is not always detected by conventional angiography. Patency of distal vessels is a positive prognostic factor in predicting salvage of the foot in patients having various treatment procedures for occlus...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198903000-00013
更新日期:1989-03-01 00:00:00
abstract::Seventeen patients with Crohn's disease requiring emergency operative procedures disclosed important factors leading to successful outcome. In seven of the ten patients not known to have Crohn's disease, the history strongly suggested this diagnosis. Two patients died; three others had major complications, including t...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197810000-00010
更新日期:1978-10-01 00:00:00
abstract::Injuries from sea urchins result from penetration of the calcareous spines into the skin. Local pain of several days' duration is the most common symptom, but systemic reaction from toxins found in certain species can occur. There is no uniformly accepted successful treatment other than cleansing the wound. Attempts t...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197704000-00029
更新日期:1977-04-01 00:00:00
abstract:BACKGROUND:There is concern that anti-affirmative-action measures will negate gains made ill educating underrepresented minority physicians and that this underrepresentation may have a negative impact on access to health care for these same underrepresented groups. METHODS:A review of the literature was completed to e...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199811000-00003
更新日期:1998-11-01 00:00:00
abstract:OBJECTIVE:To perform a needs assessment to determine the extent to which hospitalist providers recognize and intervene upon obese patients in the hospital setting. METHODS:A chart review was performed for patients admitted to the hospitalist service at Johns Hopkins Bayview Medical Center between September 1 and Octob...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181dfd715
更新日期:2010-06-01 00:00:00
abstract::We conclude that DIC can occur as a result of sickle cell crisis in the absence of sepsis and we recommend that patients with sickle cell disease, particularly those with hemoglobin SC disease, presenting in crisis should be considered at risk for the development of disseminated intravascular coagulation. With symptom...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197904000-00043
更新日期:1979-04-01 00:00:00
abstract::Increasingly the courts are expanding the scope of viable causes of action and the nature of damages, as well as the spectrum of plaintiffs to include the unborn. Generally the courts accept medically established standards of care, but on occasion courts create the standard of care. Predicated on this type of scenario...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1980-10-01 00:00:00
abstract::We have reported a case of reversible acute renal transplant failure due to the Page kidney phenomenon, which followed routine diagnostic needle biopsy. Duplex Doppler ultrasonography differentiated between allograft rejection and graft failure due to perirenal and mechanical abnormalities. Renal transplant failure ma...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199305000-00019
更新日期:1993-05-01 00:00:00
abstract::Cirrhosis affects millions of people around the world and is associated with increased morbidity and mortality. Spontaneous bacterial peritonitis (SBP) is a common complication of liver disease with cirrhosis and accounts for up to 30% of infections in patients with cirrhosis. Patients with a history of SBP and those ...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.14423/SMJ.0000000000000887
更新日期:2018-11-01 00:00:00
abstract::Perioperative consultations may play a major role in the care of surgical patients in an era of prospective payments. Since insurance reimbursement policy favors limitations in the number of consultants on a case, general medicine ("holistic") consultation services may become preferred perioperative consultants in the...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198903000-00004
更新日期:1989-03-01 00:00:00
abstract::Stercoraceous perforation of the colon is most often unsuspected and is usually diagnosed at operation or autopsy. Abdominal radiographs show large fecal masses in the rectum and sigmoid colon, and occasionally lying free in the peritoneal cavity. Free intraperitoneal air is present. We have reported a single case, wi...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197910000-00037
更新日期:1979-10-01 00:00:00
abstract::It has been claimed that sonographic techniques offer no advantages over palpation of the maternal abdomen for detection of macrosomatia. We studied a group of 498 pregnant patients, 36 (7.2%) of whom gave birth to infants having macrosomatia. A sensitivity of 67%, specificity of 97%, and positive predictive value of ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199310000-00010
更新日期:1993-10-01 00:00:00
abstract:: Acute pulmonary embolism (PE) is a common clinical condition with presentations that may vary from asymptomatic subsegmental emboli to massive vascular obstruction and shock with high risk of death. Identifying patients at highest risk for death is critical to select those who would benefit most from thrombolytic the...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/SMJ.0b013e318268dbca
更新日期:2012-10-01 00:00:00
abstract::From January 1986 to December 1987, 32 patients with recurrent colorectal cancer had second-look radioimmunoguided surgery (RIGS system). All patients had pathologic confirmation of recurrence. The RIGS system identified 81% of recurrences, and in six patients recurrent tumor was identified only by RIGS. All patients ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1989-10-01 00:00:00
abstract::Gastrosplenic fistula resulting from erosion of a primary splenic lymphoma is a rare cause of massive upper gastrointestinal hemorrhage associated with benign peptic ulcer disease, gastric Crohn's disease, gastric adenocarcinoma, and primary gastric and splenic lymphomas. Upper intestinal hemorrhage can be successfull...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2002-08-01 00:00:00
abstract::Medical inpatients in inner-city hospitals have both potentially lead-related disorders and potential lead exposure. To see whether there is substantial unexpected lead intoxication in this population, we did a cross-sectional study of 117 consecutively admitted patients to a general medical ward of an inner-city univ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199605000-00003
更新日期:1996-05-01 00:00:00
abstract::We report four cases of group A streptococcal vulvovaginitis in prepubertal children. All cases were acute in onset. This illness presents with nonspecific signs and symptoms of labial inflammation. In a suburban community, streptococcal vulvovaginitis in prepubescent girls may be more common then genital infections d...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198204000-00017
更新日期:1982-04-01 00:00:00
abstract::Appropriate use of antibiotics is enhanced by the effective application of data on antimicrobial susceptibility. A number of methods are currently available for routine determination of susceptibilities, including agar dilution, broth dilution, agar diffusion, and several semiautomated methods. If susceptibility testi...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1977-10-01 00:00:00