Abstract:
:BotulinumtoxinA (BoNT-A) is now widely established for the main approved indication of reducing glabellar lines, and is also widely used off-label to improve the appearance of wrinkles and lines in other parts of the face. The number of aesthetic procedures continues to increase as the patient population becomes more diverse, in particular with increasing numbers of people of color and men. Further developments in treatment may continue to expand the audience for BoNT-A by making procedures more comfortable and by delivering a more natural, less static appearance. These may be achieved through use of combinations of BoNT-A with other aesthetic procedures, tailoring the dose of toxin to the patient's muscle mass or by using novel injection and application techniques. Beyond amelioration of facial lines, encouraging results have been seen with the use of BoNT-A to improve the appearance of hypertrophic and keloid scars and even to prevent them. Studies have been conducted with scars in various parts of the body and further research is ongoing. Dermatological and other medical uses for BoNT-A are also active areas of research. Injections of BoNT-A have been shown to reduce signs and symptoms of acne, rosacea, and psoriasis, to reduce neuromuscular pain, and to bring about significant improvements in a number of rare diseases that are caused or exacerbated by hyperhidrosis. This paper reviews these new uses for BoNT-A, looking at the rationale for their use and discussing the results of published case studies and clinical trials. These areas have shown great promise to date, but more and larger clinical studies will be required before these treatments become a clinical reality. To this end details are also provided of clinical trials currently listed in the main clinical trials database to highlight research areas of particular interest.
journal_name
Aesthet Surg Jjournal_title
Aesthetic surgery journalauthors
Schlessinger J,Gilbert E,Cohen JL,Kaufman Jdoi
10.1093/asj/sjx005subject
Has Abstractpub_date
2017-05-01 00:00:00pages
S45-S58issue
suppl_1eissn
1090-820Xissn
1527-330Xpii
3098966journal_volume
37pub_type
杂志文章,评审abstract::Endoscopic forehead rejuvenation offers the advantages of greater patient acceptance and lower complication rates. The author describes technical modifications that make the endoscopic approach effective in a wide range of patients. Particular attention is paid to the problem of asymmetry. When the preoperative differ...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1067/maj.2001.115258
更新日期:2001-03-01 00:00:00
abstract::Fat grafting is a common procedure in aesthetic and reconstructive plastic surgery, but variable graft retention limits its utility. Unpredictable clinical outcomes with fat grafting can be explained in part by the lack of standardized protocols for harvesting, processing, and transplanting adipose tissue (AT). Histor...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,评审
doi:10.1093/asj/sju059
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND:Temple hollowing with soft tissue volume loss is well recognized in HIV lipoatrophy. Similar changes occur as part of aging, with skeletalization of the orbital rim and clipping of the eyebrow tail. OBJECTIVES:The authors report their initial experience treating temple volume loss and orbitofacial asymmetry...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X10374099
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:Canthopexies can be performed to modify the eye slant, both when the lateral canthus is lower than the medial one (congenital defect) or in case the patient asks for an almond-shaped eye (cosmetic indication). OBJECTIVES:This peculiar type of canthopexy can be defined as "dynamic canthopexy," meaning that t...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjz077
更新日期:2019-11-13 00:00:00
abstract:BACKGROUND:Capsular contracture (CC) is the most common complication following primary breast augmentation and one of the most common causes of reoperation. Various studies have suggested certain risk factors, including incision choice. OBJECTIVES:The authors investigate a possible association between the three most c...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X12444267
更新日期:2012-05-01 00:00:00
abstract:Background:Congenital, traumatic, or developmental bony vault deformities may require additional interventions rather than classical osteotomies to correct the surface structure or angulations of the nasal bones in rhinoplasty. Objectives:The aim of the study was to determine the effects of the additional osteotomies ...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjy107
更新日期:2019-01-01 00:00:00
abstract::Rhinoplasty utilizes cartilage harvested from the nasal septum as autologous graft material. Traditional dogma espouses preservation of the "L-strut" of dorsal and caudal septum, which is less resistant to axial loading than virgin septum. Considering the 90° angle between dorsal and caudal limbs, the traditional L-st...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,评审
doi:10.1093/asj/sjy301
更新日期:2019-11-13 00:00:00
abstract::The increasing use of bariatric procedures in the treatment of morbidly obese patients means that aesthetic plastic surgeons can expect to care for more and more patients who have undergone bariatric surgery. It is important for aesthetic surgeons to understand the procedures, outcomes, and possible complications to r...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,评审
doi:10.1016/j.asj.2007.09.007
更新日期:2008-01-01 00:00:00
abstract::Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL)-a new category of anaplastic large cell lymphoma associated with textured breast implants-has a distinct variation in incidence and is especially rare in Asia. We report the first case of BIA-ALCL in Korea and present its histological and genetic char...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjaa398
更新日期:2020-12-26 00:00:00
abstract:BACKGROUND:Diced cartilage is a valuable material that has recently been added to the graft options in rhinoplasty. Shaping, fixation, and resorption are the main concerns with this material. Perichondrially attached diced conchal cartilage may be a new possibility to solve some of these problems. OBJECTIVES:The autho...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X12455635
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:A significant proportion of patients seeking labiaplasty are nulliparous and may experience later changes to their labia following vaginal delivery. OBJECTIVES:In the present study, we report the long-term outcomes of a single surgeon's patient cohort who had vaginal delivery after labiaplasty. METHODS:A r...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjaa027
更新日期:2020-01-29 00:00:00
abstract::The author demonstrates his method of achieving optimal contour in the aging neck. Primary features of the technique are horizontal cuts in the vertical bands of the platysma muscle combined with a corset Z-plasty medial suture and bilateral rein plication suture. This combined procedure, which effectively lifts the s...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1016/j.asj.2007.12.006
更新日期:2008-03-01 00:00:00
abstract::The author dissected fresh cadaver heads to precisely define the surgical anatomy of the masseteric fascia, the aponeurosis of the masseter muscle, and the periosteum of the malar bone and zygomatic arch. He discovered a dense, unyielding band that is distinct from and covers the aponeurosis of the masseter muscle, wh...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1067/maj.2001.119709
更新日期:2001-09-01 00:00:00
abstract::Perioperative hyperglycemia is a well-known risk factor for surgical morbidity such as wound healing, infection, and prolonged hospitalization. This association has been reported for a number of surgical subspecialties, including plastic surgery. Specialty-specific guidelines have become increasingly available in the ...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,评审
doi:10.1093/asj/sjw064
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:The popularity of genital cosmetic procedures in women is increasing. These procedures are often assumed and promoted as having a positive effect on women's psychological well-being, particularly their self-esteem. Empirical support for these claims is lacking. OBJECTIVES:The aim of this study was to conduc...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,meta分析
doi:10.1093/asj/sjaa038
更新日期:2020-09-14 00:00:00
abstract:BACKGROUND:Studies have shown that scarring is a primary reason for patient dissatisfaction with reduction mammaplasty. OBJECTIVES:The authors prospectively evaluated patient preferences for the 3 most common breast reduction scar patterns: horizontal, vertical, and Wise. METHODS:Sixty-six patients were recruited for...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X13495868
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:Body contouring after massive weight loss has become more popular as the rate of gastric bypasses and other bariatric surgeries increases. After bariatric surgery, the buttocks not only tend to become loose and ptotic but also lose their natural fullness. OBJECTIVE:To improve buttock fullness in postbariatr...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1016/j.asj.2005.09.015
更新日期:2005-11-01 00:00:00
abstract:BACKGROUND:Given the wide application of autologous fat grafting, a new emphasis on fat processing techniques has emerged in an effort to limit unpredictable degrees of resorption often seen with this procedure. With the growing interest in regenerative medicine, approaches to supplement fat grafts with adipose-derived...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X13487371
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:Although interest in penile augmentation procedures is increasing, there is a significant lack of research into the psychological and psychosexual outcomes of these procedures. OBJECTIVES:To investigate the psychological and psychosexual outcomes of nonsurgical medical penile girth augmentation. METHODS:Th...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjy108
更新日期:2019-02-15 00:00:00
abstract:BACKGROUND:As a consumer-driven industry, cosmetic plastic surgery is subject to ebbs and flows as the economy changes. There have been many predictions about the short, intermediate, and long-term impact on cosmetic plastic surgery as a result of difficulties in the current economic climate, but no studies published i...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X10372209
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:Plastic surgeons are competing for their share of a growing but still limited market, thus making advertising an important component in a successful plastic surgery practice. OBJECTIVE:The authors evaluate the variables, characteristics, and presentation features that make print advertisements most effectiv...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X13481350
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:Adipocyte viability is affected by fat preparation and processing methods, but rigorous and objective studies of these relationships are lacking. OBJECTIVES:The authors conducted a comprehensive evaluation of variables affecting adipocyte viability prior to injection of fat at the recipient site. METHODS:L...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjw106
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:The suspension of orbicularis oculi during lower blepharoplasty presents a logical surgical addition for further support of the lid, as well as further improvement to its contour profile. It has traditionally been performed as an extension of the skin-muscle flap procedure, but more recently, and aggressivel...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjw052
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:To obtain an ideal outcome in breast augmentation procedures, breast implants may be overfilled to reduce wrinkles and improve longevity. Determination of the optimal volume for saline-filled breast implants remains problematic for plastic surgeons. OBJECTIVE:We sought to evaluate the effect of overfilling ...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1016/j.asj.2005.11.003
更新日期:2006-01-01 00:00:00
abstract::Young aesthetic surgeons may wonder, "Why care about aesthetic medicine?" The answer is based on the "five principles" of aesthetic medicine: patient acquisition, patient retention, patient optimization, patient education, and patient conversion. The explosion in new nonsurgical technologies and treatments combined wi...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjy273
更新日期:2019-06-21 00:00:00
abstract::The different types of sutures utilized in plications and for correction of diastasis during abdominoplasty are reviewed and discussed. Because correction of abdominal deformities also involves fascia and muscle advancement, this review also covers the suture materials used in muscle advancement. The selection of spec...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,评审
doi:10.1093/asj/sjy333
更新日期:2019-03-14 00:00:00
abstract:BACKGROUND:Previous anatomic studies have provided valuable information on the two-dimensional (2-D) course of the angular segment of the facial artery in the midface and its arterial connections. The third dimension (ie, the depth of the artery) is less well characterized. OBJECTIVE:The objective of the present study...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjaa176
更新日期:2020-06-27 00:00:00
abstract:BACKGROUND:The pedicled latissimus dorsi (LD) flap serves an important function in breast reconstruction, but its utility is limited by its inability to provide sufficient breast volume. OBJECTIVES:The purpose of this preliminary report was to review the techniques and outcomes of utilizing fat-grafted, volume-enhance...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjv173
更新日期:2016-02-01 00:00:00
abstract::Since their introduction into the market, breast implants have been the subject of many controversies. It is timely to examine the forces that have shaped the breast implant industry to make it what it is today. This review will concentrate more on the use of implants in aesthetic surgery rather than their use in brea...
journal_title:Aesthetic surgery journal
pub_type: 历史文章,杂志文章,评审
doi:10.1093/asj/sjy310
更新日期:2019-01-31 00:00:00
abstract:Background:Muscle activity contributes to the enhancement of facial aging deformity, blepharospasm, cerebral palsy spasticity, trismus, torticollis, and other conditions. Myotomy of the involved muscles in order to reduce the deformity has variable success rates due to muscle healing and regeneration of activity. Obje...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjx207
更新日期:2018-04-06 00:00:00