Abstract:
:The objective of this study was to assess the response of anxiety and depression symptoms to methylphenidate (MPH) treatment in patients with Asperger syndrome (AS) combined with attention deficit/hyperactivity disorder (ADHD). A group of 12 patients with AS/ADHD, aged 8-18 years, received 12 weeks of MPH treatment. The severities of ADHD, anxiety, and depression symptoms were assessed by means of the ADHD Rating Scale (ADHD-RS), Screen for Child Anxiety Related Emotional Disorders, and the Children's Depression Inventory. The severity of ADHD and depression symptoms was reduced significantly (P<0.0003 and P=0.046, respectively). No improvement in total anxiety symptoms was found, but a significant reduction was obtained in the school-related subscale of the Screen for Child Anxiety Related Emotional Disorders (P=0.0054). A positive correlation was found between the reductions in ADHD-RS and Children's Depression Inventory scores (r=0.59, P=0.039). MPH treatment may be safe, tolerable, and effective in alleviating depression and school-related anxiety symptoms in patients with AS and ADHD.
journal_name
Int Clin Psychopharmacoljournal_title
International clinical psychopharmacologyauthors
Golubchik P,Rapaport M,Weizman Adoi
10.1097/YIC.0000000000000175subject
Has Abstractpub_date
2017-09-01 00:00:00pages
289-293issue
5eissn
0268-1315issn
1473-5857journal_volume
32pub_type
临床试验,杂志文章abstract::Recent evidence has demonstrated the efficacy of pegylated interferon-alpha (IFN-alpha) in treating hepatitis C virus infection. Neuropsychiatric complications commonly occur during the course of IFN treatment, with depressive symptoms usually appearing within the first 12 weeks. Few cases of the pegylated interferon-...
journal_title:International clinical psychopharmacology
pub_type: 杂志文章
doi:10.1097/01.yic.0000170263.46008.54
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abstract::Human sexuality has three main roots: biological, motivational-affective-relational, and cognitive. Unfortunately, in women, the biological dimension is usually disregarded. Hormones are necessary, but not sufficient, factors to maintain a satisfying human libido. In women, oestrogens prime the central nervous system,...
journal_title:International clinical psychopharmacology
pub_type: 杂志文章,评审
doi:10.1097/00004850-199807006-00004
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journal_title:International clinical psychopharmacology
pub_type: 杂志文章
doi:10.1097/YIC.0b013e3280119e0c
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abstract::Twelve normal weight healthy male volunteers participated in a double-blind, placebo-controlled trial of the effects of d- and l-fenfluramine, d-amphetamine, and the interactions between the two isomers of fenfluramine with amphetamine, on cortisol secretion. d-Fenfluramine and d-amphetamine in combination produced th...
journal_title:International clinical psychopharmacology
pub_type: 临床试验,杂志文章,随机对照试验
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abstract::The aim was to evaluate the efficacy of venlafaxine extended release (ER) on characteristics of resilience, measured by the Connor-Davidson Resilience Scale, in patients with posttraumatic stress disorder (PTSD). Data were evaluated from a randomized, 6-month, international, multicenter study of adult outpatients with...
journal_title:International clinical psychopharmacology
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:International clinical psychopharmacology
pub_type: 杂志文章
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journal_title:International clinical psychopharmacology
pub_type: 杂志文章,meta分析
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journal_title:International clinical psychopharmacology
pub_type: 杂志文章
doi:10.1097/00004850-200505000-00010
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journal_title:International clinical psychopharmacology
pub_type: 临床试验,杂志文章
doi:10.1097/00004850-198704000-00011
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journal_title:International clinical psychopharmacology
pub_type: 杂志文章,meta分析
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abstract::Lithium is widely used in the treatment of bipolar disorder. Here we describe the syndrome of irreversible lithium-effectuated neurotoxicity in a patient within therapeutic doses and levels, which persisted after discontinuation of Lithium. A 50-year-old gentleman with Bipolar disorder presented with symptoms of Mania...
journal_title:International clinical psychopharmacology
pub_type: 杂志文章
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更新日期:2021-03-01 00:00:00
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journal_title:International clinical psychopharmacology
pub_type: 临床试验,杂志文章
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journal_title:International clinical psychopharmacology
pub_type: 杂志文章,随机对照试验
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journal_title:International clinical psychopharmacology
pub_type: 杂志文章
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journal_title:International clinical psychopharmacology
pub_type: 临床试验,杂志文章
doi:10.1097/00004850-200309000-00006
更新日期:2003-09-01 00:00:00
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journal_title:International clinical psychopharmacology
pub_type: 杂志文章
doi:10.1097/00004850-199100620-00005
更新日期:1991-07-01 00:00:00
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journal_title:International clinical psychopharmacology
pub_type: 杂志文章
doi:10.1097/00004850-199907000-00009
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journal_title:International clinical psychopharmacology
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:International clinical psychopharmacology
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:International clinical psychopharmacology
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:International clinical psychopharmacology
pub_type: 杂志文章,评审
doi:
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journal_title:International clinical psychopharmacology
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journal_title:International clinical psychopharmacology
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journal_title:International clinical psychopharmacology
pub_type:
doi:
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