Abstract:
:Selective beta 1-receptor blockade with atenolol (1 mg X kg-1, i.v.) was used to determine the effect of partial exercise training on diastolic coronary resistance (DCR) during sub-maximal exercise. Seven conscious dogs were studied in the untrained (UT) and partially trained (PT) conditions. The conditioning regime consisted of treadmill running 5 d X wk-1 for 4 to 5 wk. Left circumflex coronary flow, aortic pressure, and heart rate were measured, and DCR and myocardial oxygen consumption were calculated. During sub-maximal exercise, DCR in the UT dogs decreased from a resting value of 4.08 +/- 0.18 mm Hg X ml-1 X min-1 to 1.91 +/- 0.17 mm Hg X ml-1 X min-1 at a workload of 6.4 kph (speed)/16% (grade). During exercise, DCR was significantly greater in UT than in PT dogs. Atenolol significantly increased DCR at all levels of sub-maximal workload in both UT and PT dogs. However, the percent increase in DCR with atenolol was significantly greater in the PT dogs compared to UT dogs. These findings suggest that daily exercise for 4 to 5 wk may decrease beta 2-receptor activity of the coronary vasculature during sub-maximal exercise.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Liang IY,Stone HL,Gwirtz PAsubject
Has Abstractpub_date
1987-08-01 00:00:00pages
382-8issue
4eissn
0195-9131issn
1530-0315journal_volume
19pub_type
杂志文章abstract:PURPOSE:Lateral compartment osteoarthritis accompanied by abnormal knee biomechanics is frequently reported in individuals with knee osteoarthritis after anterior cruciate ligament reconstruction (ACLR). The aim of this study was to evaluate changes in knee biomechanics produced by an adjusted and unadjusted varus knee...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001201
更新日期:2017-06-01 00:00:00
abstract:PURPOSE:We investigated the development and recovery of peripheral and central fatigue during repeated cycling sprints and its influence on power output. METHODS:On six separate days, 12 healthy males performed the following tests: 1, 4, 6, 8, and 10 × 10 s sprints with 30 s of passive recovery between sprints, as wel...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000800
更新日期:2016-03-01 00:00:00
abstract:PURPOSE:This study aimed 1) to define the principal components of physical function assessed by 10 common lower extremity physical performance tests and 2) to derive a reduced-item set of physical performance tests that efficiently and accurately measures raw performance and limb symmetry on each underlying component i...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000002422
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:The purpose of this study was to investigate the influence of different cycling cadences on metabolic and kinematic parameters during subsequent running. METHODS:Eight triathletes performed two incremental tests (running and cycling) to determine maximal oxygen uptake (VO2max) and ventilatory threshold (VT) va...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00005768-200203000-00022
更新日期:2002-03-01 00:00:00
abstract:PURPOSE:This study aimed to examine the effects of footwear and neuromuscular fatigue induced by short distance trail running (TR) on running economy (RE) and biomechanics in well-trained and traditionally shod runners. METHODS:RE, vertical and leg stiffness (Kvert and Kleg), as well as foot strike angle were measured...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000981
更新日期:2016-10-01 00:00:00
abstract:INTRODUCTION/PURPOSE:Critical power (CP) is a fundamental parameter defining high-intensity exercise tolerance; however, its physiological determinants are incompletely understood. The present study determined the impact of hyperoxia on CP, the time constant of phase II pulmonary oxygen uptake kinetics (τV˙O2), and mus...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000002234
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:Compare three published methods of quantifying physical activity (total activity, peak strain, and bone-loading exposure (BLE) scores) and identify their associations with areal bone mineral density (aBMD), volumetric BMD (vBMD), and bone strength. METHODS:Postmenopausal women (N = 239; mean age: 53.8 yr) from...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,多中心研究
doi:10.1249/mss.0b013e318155a7fe
更新日期:2007-12-01 00:00:00
abstract:PURPOSE:To investigate the effects of training intensity and duration, through a range representative of training in endurance athletes, on acute recovery of autonomic nervous system (ANS) balance after exercise. METHODS:Nine highly trained (HT) male runners (VO2max 72 +/- 5 mL.kg.min(-1), 14 +/- 3 training hours per ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/mss.0b013e318060f17d
更新日期:2007-08-01 00:00:00
abstract:PURPOSE:The rapidly increasing incidence of Lyme disease has become a serious public health problem. Persistent symptoms of Lyme disease occur in over 40% of the 300,000 new cases diagnosed annually in the United States and often include debilitating musculoskeletal pain, fatigue, and poor health-related quality of lif...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000683
更新日期:2015-11-01 00:00:00
abstract:PURPOSE:This study evaluated the effect of Tai Chi Chuan (TCC) on the autonomic nervous modulation in older persons. METHODS:Twenty TCC practitioners and 20 normal controls were included in this study. The stationary state spectral heart rate variability (HRV) measures between TCC practitioners and normal controls, an...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:10.1249/01.MSS.0000099242.10669.F7
更新日期:2003-12-01 00:00:00
abstract:PURPOSE:Despite the growing research interest in vascular adaptations to exercise training over the last few decades, it remains unclear whether microvascular function in healthy subjects can be further improved by regular training. Herein, we sought to systematically review the literature and determine whether microva...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,meta分析,评审
doi:10.1249/MSS.0000000000000567
更新日期:2015-07-01 00:00:00
abstract:INTRODUCTION:Increased sedentary behavior predicts greater cardiovascular morbidity and mortality and does so independently of physical activity (PA). This association is only partially explained by body mass index (BMI) and overall body fat, suggesting mechanisms besides general increased adiposity. The purpose of thi...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3182a77220
更新日期:2014-03-01 00:00:00
abstract::Chronically increased contractile activity by low-frequency stimulation induces a transformation of fast- into slow-twitch muscle fibers in the rabbit. This transformation is progressive with the duration of the stimulation and affects various functional systems of the muscle fiber in an orderly sequence. Early change...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:
更新日期:1984-12-01 00:00:00
abstract::Nine subjects participated in an exercise program for 40 min/day, 6 days/wk. The training work rates were kept constant for the first 4 wk. The work rates were then increased to a higher level and kept constant for an additional 5 wk. During both training periods, maximum oxygen uptake (VO2max) increased for the first...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract:PURPOSE:The purpose of this study is to compare the time-frequency characteristic, using nonlinearly scaled wavelets, of the EMG signal as well as the three-dimensional (3D) knee kinematics of female and male elite soccer players performing an unanticipated cutting maneuver. METHODS:Fifteen female and 15 male elite so...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e31817b8e9e
更新日期:2008-10-01 00:00:00
abstract::A rapid, transient, rise in cytoplasmic free calcium ion concentration ([Ca2+]i-transient) couples electrical excitation to contraction in muscle. Such [Ca2+]i-transients in muscle are actually subcellular spatio-temporal events that are determined dynamically by i) diffusional fluxes of Ca2+, ii) by the binding or un...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:
更新日期:1991-10-01 00:00:00
abstract:UNLABELLED:This study examined the relationship of heart rate reserve (HRR: maximal heart rate - resting heart rate) and cardiovascular disease mortality (CVD) or all-cause mortality among healthy men. METHODS:Subjects were 27,459 healthy men, age 20-59 yr, who completed a maximal treadmill exercise test and answered ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200212000-00003
更新日期:2002-12-01 00:00:00
abstract:PURPOSE:To determine the relationships between moderate-to-vigorous physical activity (MVPA), vigorous physical activity (VPA), sedentary time, and obesity in children from 12 countries representing a wide range of human development. METHODS:The sample included 6539 children age 9-11 yr. Times in MVPA, VPA, and sedent...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,多中心研究
doi:10.1249/MSS.0000000000000649
更新日期:2015-10-01 00:00:00
abstract:PURPOSE:The best sprint performances are usually reached between the ages of 20 and 30 yr; however, even in well-trained individuals, performance continues to decrease with age. Although this inevitable decrease in performance has been related to reductions in muscular force, velocity, and power capabilities, these mea...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001039
更新日期:2016-12-01 00:00:00
abstract::This document provides an overview of selected medical issues that are important to team physicians who are responsible for the care and treatment of athletes. It is not intended as a standard of care and should not be interpreted as such. This document is only a guide and, as such, is of a general nature, consistent ...
journal_title:Medicine and science in sports and exercise
pub_type: 共识发展会议,杂志文章
doi:10.1249/MSS.0b013e31818acdcb
更新日期:2008-11-01 00:00:00
abstract:PURPOSE:To determine whether females with chronic ankle instability (CAI) demonstrated decreased dynamic postural stability compared with controls in the anterior, lateral, and medial jump directions. METHODS:Individuals with CAI (n = 24) reported a history of moderate to severe ankle sprain, two or more episodes of g...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3181e40108
更新日期:2010-12-01 00:00:00
abstract:PURPOSE:The purpose of this study was to examine the effect of regular CHO beverage ingestion and restricted fluid intake on various salivary parameters during prolonged cycle exercise. METHODS:In a randomized block design, 15 recreationally active men cycled for 2 h at 60% VO2max on three occasions, separated by 1 wk...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00005768-200012000-00013
更新日期:2000-12-01 00:00:00
abstract::Canine skeletal muscle preparations in situ contain varying mixtures of fast and slow fatigue resistant fibers. All vessels on the arterial side of the vascular bed in these preparations from the conduit arteries to the arterioles contribute to the vascular resistance. The vascular beds autoregulate at rest and during...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:10.1249/00005768-198810001-00004
更新日期:1988-10-01 00:00:00
abstract:PURPOSE:To compare the total exercise loads (intensity x volume) of the Vuelta a España and Tour de France during the last year. METHODS:Seven professional road cyclists (28 +/- 1 yr; [OV0312]O(2max): 74.6 +/- 2.2 mL.kg-1.min-1) who participated in both Tour and Vuelta during the years 1997, 1999, 2000, or 2001 were c...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.MSS.0000064999.82036.B4
更新日期:2003-05-01 00:00:00
abstract::To test whether strenuous exercise with and without caloric restriction alters LH secretion, and whether these changes are apparent in the immediate post-exercise period, LH pulse parameters were studied in four moderately trained eumenorrheic women over three successive menstrual cycles. Blood samples were obtained 5...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1995-10-01 00:00:00
abstract:PURPOSE:The purpose of this study was to establish a highly reproducible test to measure endurance performance in runners. METHODS:We evaluated the reproducibility of endurance performance during a 10-km time trial performed on a treadmill after a 90-min preload run at 65% of maximal oxygen uptake VO2max). After scree...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000121954.95892.c8
更新日期:2004-04-01 00:00:00
abstract:INTRODUCTION:Exercise-induced bronchoconstriction (EIB) is thought to result from osmotic and thermal events of air conditioning during exercise at high ventilation rates. The purpose of this study was to evaluate lung function after exercise and eucapnic voluntary hyperventilation (EVH) while breathing both room-tempe...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000158186.32450.ec
更新日期:2005-04-01 00:00:00
abstract:PURPOSE:The chronic exposure at high altitude (HA) represents an ideal model for evaluating the in vivo effects of hypobaric hypoxia. Taking advantage of the EV-K2-CNR Pyramid, this study was designed to evaluate whether acute and chronic hypoxia differently modulates the in vivo immune responses. METHODS:The study in...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000162688.54089.ce
更新日期:2005-05-01 00:00:00
abstract:INTRODUCTION:The significant sex disparity in sports-related knee injuries may be due to underlying differences in motor control. Although the development of sex-specific movement patterns is likely multifactorial, this study specifically focuses on the potential modulatory role of sex hormones. PURPOSE:This study aim...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000134
更新日期:2014-03-01 00:00:00
abstract:INTRODUCTION:This study examined the influence of a supplement matrix on the excretion pattern of nandrolone metabolites in response to ingestion of a trace amount of 19-norandrostenedione. METHODS:Ten male and nine female volunteers (mean ± SD: age = 26 ± 3 yr, height = 1.71 ± 0.09 m, body mass = 70.9 ± 13.2 kg) were...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0b013e3181bf94d6
更新日期:2010-04-01 00:00:00