Abstract：
:Accelerator mass spectrometry (AMS) was shown to be applicable for studying the penetration of organic aerosols, inhaled by laboratory mice at ultra-low concentration ca. 10(3) cm(-3). We synthesized polystyrene (PS) beads, composed of radiocarbon-labeled styrene, for testing them as model organic aerosols. As a source of radiocarbon we used methyl alcohol with radioactivity. Radiolabeled polystyrene beads were obtained by emulsifier-free emulsion polymerization of synthesized (14)C-styrene initiated by K2S2O8 in aqueous media. Aerosol particles were produced by pneumatic spraying of diluted (14)C-PS latex. Mice inhaled (14)C-PS aerosol consisting of the mix of 10(3) 225-nm particles per 1 cm(3) and 5·10(3) 25-nm particles per 1 cm(3) for 30 min every day during five days. Several millions of 225-nm particles deposited in the lungs and slowly excreted from them during two weeks of postexposure. Penetration of particles matter was also observed for liver, kidneys and brain, but not for a heart.
journal_name
Chemospherejournal_title
Chemosphereauthors
Parkhomchuk EV,Gulevich DG,Taratayko AI,Baklanov AM,Selivanova AV,Trubitsyna TA,Voronova IV,Kalinkin PN,Okunev AG,Rastigeev SA,Reznikov VA,Semeykina VS,Sashkina KA,Parkhomchuk VVdoi
10.1016/j.chemosphere.2016.05.078subject
Has Abstractpub_date
2016-09-01 00:00:00pages
80-88eissn
0045-6535issn
1879-1298pii
S0045-6535(16)30734-2journal_volume
159pub_type
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