Abstract:
BACKGROUND:Hepatic resection for hepatocellular carcinoma (HCC) is now established as the treatment most likely to yield the best outcome. We aimed to clarify the risk factors for HCC recurrence after curative resection of single HCC in patients with normal liver function (NLF). METHODS:The clinical records of 105 patients with NFL and a single HCC less than 5 cm in diameter who had undergone curative liver resection between April 2000 and January 2013 were investigated. We analyzed risk factors for recurrence of HCC. RESULTS:Forty of the 105 patients suffered recurrence of HCC, and median recurrence-free survival (RFS) was 22.0 (5.1-148.5) months after surgery, and the liver was the most frequent site of recurrence. Univariate analysis showed that limited resection (LR; p = 0.002), the indocyanine green retention rate at 15 min (p = 0.023), C-reactive protein value (p = 0.001), bilirubin value (p = 0.042), neutrophil to lymphocyte ratio (p = 0.042), operation time (p = 0.018), and amount of bleeding (p = 0.011) were associated with RFS. Multivariate analysis showed that LR (p = 0.007) was a significant risk factor associated with RFS. CONCLUSION:LR is a risk factor for HCC recurrence in patients with single-lesion HCC and NLF.
journal_name
Dig Surgjournal_title
Digestive surgeryauthors
Shimoda M,Tago K,Kato M,Aoki T,Kubota Kdoi
10.1159/000451066subject
Has Abstractpub_date
2017-01-01 00:00:00pages
281-288issue
4eissn
0253-4886issn
1421-9883pii
000451066journal_volume
34pub_type
杂志文章abstract:BACKGROUND/AIMS:Intratumoral hemodynamics or tumor perfusion is useful in understanding the pathological background of the cancer. A parameter for a non-invasive, preoperative assessment of tumor perfusion has yet to be developed. METHODS:The study included 50 patients who underwent surgery for gastric cancer. Perfusi...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000288703
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND/AIMS:The management of patients with silent or asymptomatic gallstones remains controversial. The objective of this study is to determine the complications of laparoscopic cholecystectomy performed to treat patients under 50 years of age with asymptomatic gallstones. METHOD:207 patients, 13-49 years of age ...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018876
更新日期:2000-01-01 00:00:00
abstract::The symptoms of necrolytic migratory erythema, diabetes, stomatitis, weight loss and diarrhoea represent the glucagonoma syndrome which has been recognized since the early 1970s. Because of its rarity (1 case/20-200 million population) late diagnosis is frequent which leads to a poor prognosis. The case described, ori...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018696
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Management of leakages of the gastrojejunal anastomosis after laparoscopic Roux-en-Y gastric bypass (LRYGB) can be complex. New endoscopic techniques such as covered stents and over-the-scope clips (OTCs) have been developed and are valuable alternative therapeutic options to reoperation and drainage. The ai...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000358849
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Therapeutic strategies to prevent port site recurrences in laparoscopy surgery of malignancies have not been investigated until now. METHODS:The effects of taurolidine, heparin, and povidone iodine on the growth of rat and human colon adenocarcinoma as well as gallbladder carcinoma were investigated in vitr...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018754
更新日期:1999-01-01 00:00:00
abstract::Despite the fact that laparoscopic hernia repair was already described in 1979, its value has still not been well defined. The standard treatment for uncomplicated primary hernia repair in Europe is an open anterior approach (i.e. Shouldice), and 'tension-free' mesh plug repair in the USA. At present, posterior mesh i...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000018611
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Morbidity following pancreaticoduodenectomy (PD) has been reported to remain high. This study sought to measure the peak Hounsfield units (HUs) of visceral attenuation in patients undergoing PD and to assess the quality of adipocytes by comparing these measurements with perioperative factors. METHODS:Patien...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000505060
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:The optimal treatment for acute complicated diverticulitis is still a matter of debate. We evaluated outcomes of primary anastomosis with proximal diversion (PAD) versus Hartman's procedure (HP) in acute diverticulitis. METHODS:Using the National Inpatient Sample database, we examined the clinical data of p...
journal_title:Digestive surgery
pub_type: 杂志文章,多中心研究
doi:10.1159/000342549
更新日期:2012-01-01 00:00:00
abstract::Ectopic pancreas is an uncommon condition and is usually found in the gastrointestinal tract, such as stomach, duodenum and jejunum. However, ectopic pancreas in the ampulla of Vater is rare and its clinical presentations may be similar to periampullary cancer. It is difficult to diagnose preoperatively. We present su...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000096158
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:The optimal management approach to pancreatic serous cystic neoplasms (SCNs) is still evolving. METHODS:Consecutive patients with SCN managed at the Liverpool Pancreas Cancer Centre between 2000 and 2013 were retrospectively reviewed. RESULTS:There were 64 patients consisting of 39 women (60.9%) and 25 men...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000442094
更新日期:2016-01-01 00:00:00
abstract::Resection of liver metastases for locally resectable pancreatic cancer has rarely been performed. Recently, promising results regarding morbidity and mortality as well as long-term survival have been shown. Thus, we conducted a systematic review of the literature on pancreatic cancer resection with associated liver me...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000184739
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND/AIMS:Widespread clinical application of islet transplantation remains restricted, because of insufficient methods to prevent rejection and autoimmune destruction of islet grafts. In this study we demonstrate long-term function of islets of Langerhans within a capsule of porcine chondrocytes which may serve a...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000050130
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:Perianal warts are common, and may be extensive. Electrocoagulation is a recognised management option. METHOD:A 20-year-old male underwent electrocautery of extensive perianal warts. He presented 3 months postoperatively with constipation and inability to defecate. Examination revealed severe perianal stric...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018856
更新日期:2000-01-01 00:00:00
abstract:INTRODUCTION:Little data is available on the prognosis of esophageal cancer (EC) in Iran. We studied the short- and long-term survival of EC patients treated at the Cancer Institute of Iran. METHODS:619 patients were followed who had been operated in the years 1997-2006. The 1-month to 5-year survival rates of EC and ...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000354854
更新日期:2013-01-01 00:00:00
abstract::Partial liver resections are the treatment of choice for patients with a malignant liver or bile duct tumor. The most frequent indications for partial liver resections are colorectal metastasis, hepatocellular carcinoma (HCC) and cholangiocarcinoma. Liver resection is the only therapy with a chance for cure in these p...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000103656
更新日期:2007-01-01 00:00:00
abstract:INTRODUCTION:In the management of pancreatic cystic neoplasms (PCN), size plays a crucial role as the expression of disease progression. While many evidences regarding the natural history of growing pancreatic cysts exist, almost no data are available regarding cysts with a reduction in size. METHODS:Radiological and ...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000485199
更新日期:2018-01-01 00:00:00
abstract:AIM:To investigate the degree to which specialisation or case-load of the surgeon is associated with the number of lymph nodes isolated from pathology specimens after right-sided hemicolectomy. METHOD:Data from 6 hospitals with well-defined catchment areas included in the Uppsala/Örebro Regional Oncology Centre Colon ...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000354857
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND/AIMS:Strictureplasty (SP) or miniresective 'bowel-sparing' techniques (MR) can prevent the risk of intestinal stomia and short bowel syndrome in patients affected by Crohn's disease (CD). The aim of this study was to analyze the perioperative morbidity and mortality in 104 of 138 consecutive patients treated...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018845
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Curative treatment for gastric cancer (GC) comprising gastrectomy with systematic lymph node dissection can result in postoperative complications. Postoperative pneumonia is sometimes fatal, like surgery-related complications such as anastomotic leakage. In this retrospective study, we analyzed a multi-insti...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000506940
更新日期:2020-01-01 00:00:00
abstract::A 64-year-old man with Muir-Torre syndrome (MTS), a condition characterized by the association of multiple sebaceous tumours and kerato-acanthomas with internal malignancies, developed a carcinoma of the ampulla of Vater. This is the 2nd reported ampullary carcinoma in 205 reported cases of MTS, suggesting a higher pr...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000052010
更新日期:2002-01-01 00:00:00
abstract:AIM:To prove further the safety of primary closure of the common bile duct. METHOD:Twenty patients among 99 common bile duct explorations underwent primary closure. Pre- and postoperative liver function test, ultrasound and intraoperative cholangiography data, operation time, postoperative complications and the length...
journal_title:Digestive surgery
pub_type: 临床试验,杂志文章
doi:10.1159/000018706
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:The prognosis of patients with pancreatic cancer is poor. This is mainly caused by the late diagnosis, the aggressive biology and the lack of effective treatment modalities. Adenoviral gene therapy has the potential to selectively treat both primary tumor and (micro)metastatic tissue. METHODS:This review pr...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000145981
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND/AIM:Delay of laparoscopic cholecystectomy after the diagnosis of biliary colic may increase the probability of recurrent emergency admission while awaiting elective cholecystectomy. The aim of this study was to compare the possible advantages and safety of urgent laparoscopic cholecystectomy (ULC) with elect...
journal_title:Digestive surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000085300
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND/AIMS:The surgical treatment of duodenogastric reflux (DGR), resistant to medical therapy, in patients with intact stomach is difficult to standardize. The aim of this study is to present our experience on 5 patients, all cholecystectomized, with severe DGR disease treated surgically. METHODS:Out of a group ...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018583
更新日期:1998-01-01 00:00:00
abstract:INTRODUCTION:To determine the best imaging modality for preoperative detection, characterization and measurement of colorectal liver metastases (CRLM) after neoadjuvant chemotherapy (NAC). METHODS:A total of 79 lesions in 15 patients with CRLM were included. Following NAC, all patients received multislice liver CT (MS...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000322390
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:The prevalence and significance of joint symptoms appearing in patients with ulcerative colitis (UC) following a colectomy are unclear. AIM:We investigated the relationship between joint symptoms during steroid tapering following an ileal pouch-anal anastomosis (IPAA) and the cumulative risk for developing ...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000093495
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND/AIM:In the present study, we investigated the acute and late phases of splenic circulation after spleen-preserving distal pancreatectomy (SPDP) involving the division of splenic vessels. METHODS:An acute phase of splenic circulation was evaluated by laser flow meter and the late phase was estimated by (99m)...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000051952
更新日期:2000-01-01 00:00:00
abstract::The authors reported the magnetic resonance imaging (MRI) detection of manganese (Mn) deposition in the basal ganglia of a pancreatoduodenectomized patient following 30-day parenteral nutrition. A multi-trace element supplement solution including 20 micromol Mn/day was parenterally administered for 30 days postoperati...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018830
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:The reduction in plasma cholesterol with increase in large and lower dense LDL (pattern A) obtained by statins is usually associated with a prompt reduction in cardiovascular risk, but after bariatric surgery for morbid obesity a delay of some years is observed. No data regarding LDL pattern are available in...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000068861
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND/AIMS:It has recently been reported that rebamipide (OPC-12759) inhibits inflammatory cytokines and activation of neutrophils. The aim of the present study was to investigate the effects of preoperative administration of rebamipide on parameters of systemic inflammatory response syndrome (SIRS) and serum leve...
journal_title:Digestive surgery
pub_type: 临床试验,杂志文章
doi:10.1159/000073645
更新日期:2003-01-01 00:00:00