Abstract：
:We investigated word-level reading circuits in skilled deaf readers (N=14; mean reading age=19.5years) and less skilled deaf readers (N=14; mean reading age=12years) who were all highly proficient users of American Sign Language. During fMRI scanning, participants performed a semantic decision (concrete concept?), a phonological decision (two syllables?), and a false-font control task (string underlined?). No significant group differences were observed with the full participant set. However, an analysis with the 10 most and 10 least skilled readers revealed that for the semantic task (vs. control task), proficient deaf readers exhibited greater activation in left inferior frontal and middle temporal gyri than less proficient readers. No group differences were observed for the phonological task. Whole-brain correlation analyses (all participants) revealed that for the semantic task, reading ability correlated positively with neural activity in the right inferior frontal gyrus and in a region associated with the orthography-semantics interface, located anterior to the visual word form area. Reading ability did not correlate with neural activity during the phonological task. Accuracy on the semantic task correlated positively with neural activity in left anterior temporal lobe (a region linked to conceptual processing), while accuracy on the phonological task correlated positively with neural activity in left posterior inferior frontal gyrus (a region linked to syllabification processes during speech production). Finally, reading comprehension scores correlated positively with vocabulary and print exposure measures, but not with phonological awareness scores.
journal_name
Brain Langjournal_title
Brain and languageauthors
Emmorey K,McCullough S,Weisberg Jdoi
10.1016/j.bandl.2016.06.007subject
Has Abstractpub_date
2016-09-01 00:00:00pages
11-20eissn
0093-934Xissn
1090-2155pii
S0093-934X(15)30084-5journal_volume
160pub_type
杂志文章abstract：:Previous studies have identified several brain regions that appear to be involved in the acquisition of novel word forms. Standard word-by-word presentation is often used although exposure to a new language normally occurs in a natural, real world situation. In the current experiment we investigated naturalistic langu...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2009.12.005
更新日期：2010-04-01 00:00:00
abstract：:There is substantial neural evidence for the role of morphology (word-internal structure) in visual word recognition. We extend this work to auditory word recognition, drawing on recent evidence that phoneme prediction is central to this process. In a magnetoencephalography (MEG) study, we crossed morphological comple...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2013.11.004
更新日期：2014-02-01 00:00:00
abstract：:A number of recent studies have argued that grammatical illusions can arise in the process of completing linguistic dependencies, such that unlicensed material is temporarily treated as licensed due to the presence of a potential licensor that is semantically appropriate but in a syntactically inappropriate position. ...
journal_title：Brain and language
pub_type： 临床试验,杂志文章
doi：10.1016/j.bandl.2008.10.002
更新日期：2009-01-01 00:00:00
abstract：:The widely known discovery of mirror neurons in macaques shows that premotor and parietal cortical areas are not only involved in executing one's own movement, but are also active when observing the action of others. The goal of this essay is to critically evaluate the substance of functional magnetic resonance imagin...
journal_title：Brain and language
pub_type： 杂志文章,评审
doi：10.1016/j.bandl.2007.11.002
更新日期：2009-01-01 00:00:00
abstract：:Subjects were asked to indicate which item of a word/nonword pair was a word. On critical trials the nonword was a pseudohomophone of the word. RTs of dyslexics were shorter in blocks of trials in which a congruent auditory prime was simultaneously presented with the visual stimuli. RTs of normal readers were longer f...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1006/brln.1998.1996
更新日期：1999-02-01 00:00:00
abstract：:The study describes the sulcal and gyral topography, variability, and left-right asymmetry of the parietal operculum. Eighty postmortem hemispheres as well as sagittal magnetic resonance images from 20 health volunteers (40 hemispheres) were evaluated. Four different types of parietal opercular sulcus topography were ...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/0093-934x(90)90135-4
更新日期：1990-05-01 00:00:00
abstract：:Many aspects of subcortical aphasias are not accounted for by a unique pathophysiological mechanism; rather the diversity of the observed symptoms suggests that many functional ensembles, more or less related, to language functions may be disturbed by subcortical lesions. However, such disorders are only moderate in i...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1006/brln.1997.1806
更新日期：1997-07-01 00:00:00
abstract：:Forward masked word primes that differed from the target in the initial, the final or both the initial and final positions tended to slow target decision latencies and there were no significant differences among prime types. After forward masked nonword primes we observed non significant facilitation when primes diffe...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/S0093-934X(03)00455-3
更新日期：2004-07-01 00:00:00
abstract：:The role of neuronal oscillations during language comprehension is not yet well understood. In this paper we review and reinterpret the functional roles of beta- and gamma-band oscillatory activity during language comprehension at the sentence and discourse level. We discuss the evidence in favor of a role for beta an...
journal_title：Brain and language
pub_type： 杂志文章,评审
doi：10.1016/j.bandl.2015.01.003
更新日期：2015-09-01 00:00:00
abstract：:To understand the neural basis of human speech control, extensive research has been done using a variety of methodologies in a range of experimental models. Nevertheless, several critical questions about learned vocal motor control still remain open. One of them is the mechanism(s) by which neurotransmitters, such as ...
journal_title：Brain and language
pub_type： 杂志文章,评审
doi：10.1016/j.bandl.2011.12.009
更新日期：2012-09-01 00:00:00
abstract：:Intraoperative direct electrical stimulation (DES) is increasingly used in patients operated on for tumours in eloquent areas. Although a positive impact of DES on postoperative linguistic outcome is generally advocated, information about the neurolinguistic methods applied in awake surgery is scarce. We developed for...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2014.10.011
更新日期：2015-01-01 00:00:00
abstract：:Gestural communication is a modality considered in the literature as a candidate for determining the ancestral prerequisites of the emergence of human language. As reported in captive chimpanzees and human children, a study in captive baboons revealed that a communicative gesture elicits stronger degree of right-hand ...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2008.10.004
更新日期：2009-03-01 00:00:00
abstract：:The present case continues the series of anomia treatment studies with contextual priming (CP), being the second in-depth treatment study conducted for an individual suffering from semantically based anomia. Our aim was to acquire further evidence of the facilitation and interference effects of the CP treatment on sem...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2005.02.003
更新日期：2005-11-01 00:00:00
abstract：:Compound nouns have multiple meanings in English. The purpose of this study was to explore when children know that compound nouns refer to two objects, one ideally interacting with the other (e.g., "fish shoes" are shoes with fish on them, not next to them). Thirty-five English-speaking three- and four-year-old childr...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/s0093-934x(02)00519-9
更新日期：2003-01-01 00:00:00
abstract：:Formal lexical errors are relatively rare in the production of aphasic patients. In this study, we report the case of DW, who makes a high proportion of these errors. A few other cases have previously been reported, but DW shows a number of distinguishing characteristics. First, formal lexical errors are made in spell...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/s0093-934x(02)00022-6
更新日期：2002-11-01 00:00:00
abstract：:We used fMRI to examine patterns of brain activity associated with component processes of visual word recognition and their relationships to individual differences in reading skill. We manipulated both the judgments adults made on written stimuli and the characteristics of the stimuli. Phonological processing led to a...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2011.12.011
更新日期：2012-03-01 00:00:00
abstract：:The functional specificity of different brain areas recruited in auditory language processing was investigated by means of event-related functional magnetic resonance imaging (fMRI) while subjects listened to speech input varying in the presence or absence of semantic and syntactic information. There were two sentence...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1006/brln.2000.2313
更新日期：2000-09-01 00:00:00
abstract：:Previous studies suggest that anatomical anomalies [Foundas, A. L., Bollich, A. M., Corey, D. M., Hurley, M., & Heilman, K. M. (2001). Anomalous anatomy of speech-language areas in adults with persistent developmental stuttering. Neurology, 57, 207-215; Foundas, A. L., Corey, D. M., Angeles, V., Bollich, A. M., Crabtr...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2007.04.005
更新日期：2008-02-01 00:00:00
abstract：:Ninety-one adult aphasics of both sexes were studied before and after a 3-month period of language therapy. Although no initial sex difference was found in severity of language disorders, females within the global aphasic group showed significantly greater improvement in three tests of language comprehension. It is su...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/0093-934x(85)90081-1
更新日期：1985-07-01 00:00:00
abstract：:Phonation is a fundamental feature of human communication. Control of phonation in the context of speech-language disturbances has traditionally been considered a characteristic of lesions to subcortical structures and pathways. Evidence suggests however, that cortical lesions may also implicate phonation. We carried ...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2012.06.008
更新日期：2012-10-01 00:00:00
abstract：:Skilled visual word recognition is thought to rely upon a particular region within the left fusiform gyrus, the visual word form area (VWFA). We investigated whether an individual (AA1) with pure alexia resulting from acquired damage to the VWFA territory could learn an alphabetic "FaceFont" orthography, in which face...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2013.11.005
更新日期：2014-02-01 00:00:00
abstract：:The traditional clinical picture for English nonfluent aphasics has generally presented the deficit as one of total loss of control over grammatical morphology, with some sparing of word order. This is at odds with recent research involving nonfluent aphasic speakers of highly inflected languages, which has shown that...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/0093-934x(91)90156-u
更新日期：1991-08-01 00:00:00
abstract：:Bilinguals require a high degree of cognitive control to select the language intended for speaking and inhibit the unintended. Previous neuroimaging studies have not teased apart brain regions for generating the intention to use a given language, and those for speaking in that language. Separating these two phases can...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2015.03.004
更新日期：2015-05-01 00:00:00
abstract：BACKGROUND:Repetitive transcranial magnetic stimulation (rTMS) has been used experimentally to facilitate naming abilities in individuals with chronic post-stroke aphasia. However, little is known about how rTMS confers clinical improvement, hampering its therapeutic value. The present study investigated the characteri...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2019.02.005
更新日期：2019-05-01 00:00:00
abstract：:Ten aphasic and five control subjects were administered an auditory comprehension task similar to Levels I-IV of the Revised Token Test under conditions of 0, 5, 10, and 20 sec of imposed response delay. Responses were evaluated in terms of performance accuracy and response time. Aphasic subjects' response accuracy wa...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/0093-934x(86)90054-4
更新日期：1986-11-01 00:00:00
abstract：:Linguistic analysis suggests that numeral classifiers carry quantity information. However, previous neuroimaging studies have shown that classifiers did not elicit higher activation in the intraparietal sulcus (IPS), associated with representation of numerical magnitude, than tool nouns did. This study aimed to contro...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2017.10.007
更新日期：2018-01-01 00:00:00
abstract：:The study of the neural basis of syntactic processing has greatly benefited from neuroimaging techniques. Research on syntactic processing in bilinguals has used a variety of techniques, including mainly functional magnetic resonance imaging (fMRI) and event-related potentials (ERP). This paper reports on a functional...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2011.09.009
更新日期：2012-05-01 00:00:00
abstract：:Children with congenital left hemisphere damage due to perinatal stroke are capable of acquiring relatively normal language functions despite experiencing a cortical insult that in adults often leads to devastating lifetime disabilities. Although this observed phenomenon is accepted, its neurobiological mechanisms are...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2009.09.001
更新日期：2010-08-01 00:00:00
abstract：:This research examines the nature of acoustic-phonetic impairments found in aphasia, and the reliability of patient performance on phoneme discrimination and identification tasks. Aphasic patients were tested on three phoneme discrimination tasks examining their ability to discriminate items on the basis of contrasts ...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1006/brln.1996.0019
更新日期：1996-02-01 00:00:00
abstract：:We report an experiment that evaluates whether BLANK or an unrelated prime is a more suitable baseline for assessing priming for an ERP study. Sixteen subjects performed a lexical decision task with a 1 s prime-target stimulus onset asynchrony. Increased amplitude for the N400 was observed for targets in the unrelated...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2005.08.002
更新日期：2006-04-01 00:00:00
