Dopamine regulation of human speech and bird song: a critical review.

Abstract:

:To understand the neural basis of human speech control, extensive research has been done using a variety of methodologies in a range of experimental models. Nevertheless, several critical questions about learned vocal motor control still remain open. One of them is the mechanism(s) by which neurotransmitters, such as dopamine, modulate speech and song production. In this review, we bring together the two fields of investigations of dopamine action on voice control in humans and songbirds, who share similar behavioral and neural mechanisms for speech and song production. While human studies investigating the role of dopamine in speech control are limited to reports in neurological patients, research on dopaminergic modulation of bird song control has recently expanded our views on how this system might be organized. We discuss the parallels between bird song and human speech from the perspective of dopaminergic control as well as outline important differences between these species.

journal_name

Brain Lang

journal_title

Brain and language

authors

Simonyan K,Horwitz B,Jarvis ED

doi

10.1016/j.bandl.2011.12.009

subject

Has Abstract

pub_date

2012-09-01 00:00:00

pages

142-50

issue

3

eissn

0093-934X

issn

1090-2155

pii

S0093-934X(11)00197-0

journal_volume

122

pub_type

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