Abstract：
BACKGROUND:Hand, foot and mouth disease (HFMD) is a rising public health issue in the Asia-Pacific region. Numerous studies have tried to quantify the relationship between meteorological variables and HFMD but with inconsistent results, in particular for temperature. We aimed to characterize the relationship between temperature and HFMD in various locations and to investigate the potential heterogeneity. METHODS:We retrieved the daily series of childhood HFMD counts (aged 0-12 years) and meteorological variables for each of 143 cities in mainland China in the period 2009-2014. We fitted a common distributed lag nonlinear model allowing for over dispersion to each of the cities to obtain the city-specific estimates of temperature-HFMD relationship. Then we pooled the city-specific estimates through multivariate meta-regression with city-level characteristics as potential effect modifiers. RESULTS:We found that the overall pooled temperature-HFMD relationship was shown as an approximately inverted V shape curve, peaking at the 91th percentile of temperature with a risk ratio of 1.30 (95% CI: 1.23-1.37) compared to its 50th percentile. We found that 68.5% of the variations of city-specific estimates was attributable to heterogeneity. We identified rainfall and altitude as the two main effect modifiers. CONCLUSIONS:We found a nonlinear relationship between temperature and HFMD. The temperature-HFMD relationship varies depending on geographic and climatic conditions. The findings can help us deepen the understanding of weather-HFMD relationship and provide evidences for related public health decisions.
journal_name
Environ Intjournal_title
Environment internationalauthors
Xiao X,Gasparrini A,Huang J,Liao Q,Liu F,Yin F,Yu H,Li Xdoi
10.1016/j.envint.2016.11.021subject
Has Abstractpub_date
2017-03-01 00:00:00pages
102-109eissn
0160-4120issn
1873-6750pii
S0160-4120(16)30431-7journal_volume
100pub_type
杂志文章abstract：:Caenorhabditis elegans is a free-living soil nematode that is commonly used as a model for toxicity tests. The aim of this study was to investigate the toxicity of seven organic pollutants: four azaarenes (quinoline, acridine, phenazine, and 1,10-phenanthroline), short-chain chlorinated paraffins, and two organochlori...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2007.03.001
更新日期：2007-08-01 00:00:00
abstract：:On February 12-15, 2001, more than 200 scientists, engineers, decision makers, and educators participated in a conference on the "Future Directions in Air Quality Research: Ecological, Atmospheric, Regulatory/Policy, and Educational Issues." Important perspectives are summarized from the keynote addresses of noted sci...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/S0160-4120(02)00155-1
更新日期：2003-06-01 00:00:00
abstract：:The distribution of dissolved rare earth elements (REE) in the Rhine River, Germany, shows the anthropogenic gadolinium (Gd) microcontamination that is commonly observed in rivers in densely populated countries with a highly evolved health care system. However, the Rhine River also carries anomalously high concentrati...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2011.02.018
更新日期：2011-07-01 00:00:00
abstract：:Per- and polyfluoroalkyl substances (PFASs) are ubiquitous in the environment, making it inevitable for humans to be exposed to these pollutants. The exposure begins while in utero and continues in infancy, during the potentially most sensitive early stages of life. This review summarizes the current knowledge on pre-...
journal_title：Environment international
pub_type： 杂志文章,评审
doi：10.1016/j.envint.2020.106012
更新日期：2020-11-01 00:00:00
abstract：:Lead (Pb) is an environmental pollutant with a toxicity that is a serious public health problem. The aim of this research was to evaluate the associations between Pb exposure and morphometric, hematological and biochemical parameters, mRNA expression of the P53, SOD1, ALAD, TNF and INF-γ genes, ALAD polymorphisms (db ...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2019.05.003
更新日期：2019-09-01 00:00:00
abstract：:Human exposure to dechloranes has been evaluated in Western Europe (France) with the analysis of Dechlorane Plus (DP), Dechloranes (Dec) 602, 603 and 604, Chlordene Plus (CP) and Mirex in 48 serum samples collected between 2003 and 2005. While no production source has been identified in Europe until now, detection fre...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2013.12.014
更新日期：2014-04-01 00:00:00
abstract：:Personal exposure measurements of radio frequency electromagnetic fields are important for epidemiological studies and developing prediction models. Minimizing biases and uncertainties and handling spatial and temporal variability are important aspects of these measurements. This paper reviews the lessons learnt from ...
journal_title：Environment international
pub_type： 杂志文章,评审
doi：10.1016/j.envint.2016.06.023
更新日期：2016-09-01 00:00:00
abstract：:Although various pesticides were used globally, the pesticides profiles in human blood serum remain largely unknown. We determined pesticide exposure profiles using solid-phase extraction and gas chromatography tandem with triple quadrupole mass spectrometry in 200 human blood serum samples from the adult population i...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2017.03.004
更新日期：2017-05-01 00:00:00
abstract：BACKGROUND:Accurate estimation of nitrogen dioxide (NO2) and nitrogen oxide (NOx) concentrations at high spatiotemporal resolutions is crucial for improving evaluation of their health effects, particularly with respect to short-term exposures and acute health outcomes. For estimation over large regions like California,...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2019.04.057
更新日期：2019-07-01 00:00:00
abstract：:Oxidative stress in humans is affected by the health and nutritional status as well as exposure to external environmental factors. To evaluate the effects of external factors, an assessment of baseline levels as well as diurnal variations in oxidative stress status of healthy individuals is needed. In this study, we e...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2018.12.009
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:Health impact assessment (HIA) of exposure to air pollution is commonly based on city level (fine) particle concentration and may underestimate health consequences of changing local traffic. Exposure to traffic-related air pollution can be assessed at a high resolution by modelling levels of nitrogen dioxide...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2018.09.050
更新日期：2018-12-01 00:00:00
abstract：:The cabin of an automobile can be considered to be a part of the living environment because many people spend long periods of time during business, shopping, recreation or travel activities. However, little is known about the interior air contamination due to organic compounds diffusing from the interior materials use...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2005.04.009
更新日期：2006-01-01 00:00:00
abstract：:Health effects of air pollution, especially particulate matter (PM), have been widely investigated. However, most of the studies rely on few monitors located in urban areas for short-term assessments, or land use/dispersion modelling for long-term evaluations, again mostly in cities. Recently, the availability of fine...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2016.11.024
更新日期：2017-02-01 00:00:00
abstract：:Green space has a variety of health benefits. However, little is known about its impact on autism, the fastest-growing neurodevelopmental disorder in children. This study examined the relationship between green space and childhood autism prevalence. Autism count data in 2010 were obtained for 543 of ~560 public elemen...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2017.07.010
更新日期：2017-10-01 00:00:00
abstract：:Oil spills are serious environmental issues that potentially can cause adverse effects on marine ecosystems. In some marine areas, like the Baltic Sea, there is a large number of wrecks from the first half of the 20th century, and recent monitoring and field work have revealed release of oil from some of these wrecks....
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2019.02.037
更新日期：2019-05-01 00:00:00
abstract：:Being persistent, toxic, and bio-accumulative, Mercury (Hg) seriously affects the environment and human health. Due to Hg's attribute of long-range environmental transport across national borders, especially through atmospheric transport, no country can fully protect its environment and human health with its own effor...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2014.10.023
更新日期：2015-02-01 00:00:00
abstract：:A novel technique, gas chromatography-UV spectrometry (GC-UV), was used to quantify volatile organic compounds (VOCs) in settled dust from 389 residences in Sweden. The dust samples were thermally desorbed in an inert atmosphere and evaporated compounds were concentrated by solid phase micro extraction and separated b...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2005.04.003
更新日期：2005-10-01 00:00:00
abstract：BACKGROUND:While it is known that perfluoroalkyl substances (PFASs) induce liver toxicity in experimental studies, the evidence of an association in humans is inconsistent. OBJECTIVE:The main aim of the present study was to examine the association of PFAS concentrations and markers of liver function using panel data. ...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2018.04.052
更新日期：2018-08-01 00:00:00
abstract：:Human cornea is highly susceptible to damage by dust. Continued daily exposure to housedust has been associated with increasing risks of corneal injury, however, the underlying mechanism has not been elucidated. In this study, a composite housedust sample was tested for its cytotoxicity on primary human corneal epithe...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2016.01.008
更新日期：2016-04-01 00:00:00
abstract：:Meta-analysis approaches can be used to assess the human risks due to exposure to environmental chemicals when there are numerous high-quality epidemiologic studies of priority outcomes in a database. However, methodological issues related to how different studies report effect measures and incorporate exposure into t...
journal_title：Environment international
pub_type： 杂志文章,meta分析
doi：10.1016/j.envint.2020.105810
更新日期：2020-09-01 00:00:00
abstract：:Airborne microorganisms (AM), vital components of particulate matters (PM), are widespread in the atmosphere. Since some AM have pathogenicity, they can lead to a wide range of diseases in human and other organisms, meanwhile, some AM act as cloud condensation nuclei and ice nuclei which let them can affect the climat...
journal_title：Environment international
pub_type： 杂志文章,评审
doi：10.1016/j.envint.2018.01.007
更新日期：2018-04-01 00:00:00
abstract：:Elevated blood pressure in childhood is an important risk factor for hypertension in adulthood. Environmental exposures have been associated with elevated blood pressure over the life course and exposure to mercury (Hg) has been linked to cardiovascular effects in adults. As subclinical vascular changes begin early in...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2020.106201
更新日期：2021-01-01 00:00:00
abstract：:A large number of aromatic compounds and organic nitriles, the two groups of compounds covered in this review, are intermediates, products, by-products or waste products of the chemical and pharmaceutical industries, agriculture and the processing of fossil fuels. The majority of these synthetic substances (xenobiotic...
journal_title：Environment international
pub_type： 杂志文章,评审
doi：10.1016/j.envint.2008.07.018
更新日期：2009-01-01 00:00:00
abstract：:A coupled numerical model of the atmospheric thermo-hydrodynamics and pollutant photochemical transport is described. This model can be used to study the complex relationships between the chemical and thermo-hydrodynamic processes in the atmosphere of urban areas with an emphasis on photochemical ozone formation. Prel...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/S0160-4120(02)00173-3
更新日期：2003-06-01 00:00:00
abstract：:Soil amendment with biochars is currently being studied worldwide as a sustainable agricultural practice to improve soil and water quality, increase crop productivity, and augment soil carbon storage. However, the formation of polyaromatic hydrocarbons (PAHs) during biochar production is inevitable. Therefore, it is c...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2019.06.009
更新日期：2019-09-01 00:00:00
abstract：:Long-term air quality data with high temporal and spatial resolutions are needed to understand some important processes affecting the air quality and corresponding environmental and health effects. The annual and diurnal variations of each criteria pollutant including PM2.5 and PM10 (particulate matter with aerodynami...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2015.11.003
更新日期：2016-01-01 00:00:00
abstract：:Volatile organic compounds (VOCs) are the major pollutants in indoor air, which significantly impact indoor air quality and thus influencing human health. A long-term exposure to VOCs will be detrimental to human health causing sick building syndrome (SBS). Photocatalytic oxidation of VOCs is a cost-effective technolo...
journal_title：Environment international
pub_type： 杂志文章,评审
doi：10.1016/j.envint.2007.02.011
更新日期：2007-07-01 00:00:00
abstract：:Surface sediment samples were collected from various locations in the Mumbai and Kochi harbours, west coast of India, to assess the presence of butyltin compounds. Tributyltin (TBT) and dibutyltin (DBT) varied from 16 to 16,816 ng/g dry wt. and from undetected to 469 ng/g dry wt., respectively, of the sediment in Koch...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2005.08.020
更新日期：2006-02-01 00:00:00
abstract：:The aims of this study are to explore metal contamination in food with respect to variations in: i) the levels found over a period of eleven months and/or ii) by food types; and iii) to report patterns in reporting between countries. The frequencies of reported cases of metal ion contamination were < or = 25% of total...
journal_title：Environment international
pub_type： 杂志文章
doi：10.1016/j.envint.2009.05.003
更新日期：2009-10-01 00:00:00
abstract：:It is becoming increasingly clear that the genetic diversity and abundance of antimicrobial resistance (AMR) in non-clinical settings has been underestimated and that the environment plays an integral role in enabling the development of AMR. Due to specific demographic and environmental factors the Gulf Cooperation Co...
journal_title：Environment international
pub_type： 杂志文章,评审
doi：10.1016/j.envint.2018.06.030
更新日期：2018-12-01 00:00:00
