Abstract:
:Background. Blunt chest wall trauma accounts for over 10% of all trauma patients presenting to emergency departments worldwide. When the injury is not as severe, deciding which blunt chest wall trauma patients require a higher level of clinical input can be difficult. We hypothesized that patient factors, injury patterns, analgesia, postural condition, and positive airway pressure influence outcomes. Methods. The study population consisted of patients hospitalized with at least 3 rib fractures (RF) and at least one pulmonary contusion and/or at least one pneumothorax lower than 2 cm. Results. A total of 140 patients were retrospectively analyzed. Ten patients (7.1%) were admitted to intensive care unit (ICU) within the first 72 hours, because of deterioration of the clinical conditions and gas exchange with worsening of chest X-ray/thoracic ultrasound/chest computed tomography. On univariable analysis and multivariable analysis, obliged orthopnea (p = 0.0018) and the severity of trauma score (p < 0.0002) were associated with admission to ICU. Conclusions. Obliged orthopnea was an independent predictor of ICU admission among patients incurring non-life-threatening blunt chest wall trauma. The main therapeutic approach associated with improved outcome is the prevention of pulmonary infections due to reduced tidal volume, namely, upright postural condition and positive airway pressure.
journal_name
Can Respir Jjournal_title
Canadian respiratory journalauthors
Bellone A,Bossi I,Etteri M,Cantaluppi F,Pina P,Guanziroli M,Bianchi A,Casazza Gdoi
10.1155/2016/3257846subject
Has Abstractpub_date
2016-01-01 00:00:00pages
3257846eissn
1198-2241issn
1916-7245journal_volume
2016pub_type
杂志文章abstract:BACKGROUND:Interleukin (IL)-10 is a pleiotropic cytokine released from various cells, including T cells. Although IL-10 is suggested to inhibit allergic responses, its role in asthma remains uncertain. The purpose of the present study was to compare the profile of IL-10 in circulating T cells from stable atopic asthmat...
journal_title:Canadian respiratory journal
pub_type: 临床试验,杂志文章
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pub_type: 历史文章,杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章,评审
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更新日期:2012-01-01 00:00:00
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